Immunology for University Students
13.6K views | +0 today
Follow
Immunology for University Students
Resources and Material for Lecturers and Students - Immunology (University level)
Curated by Alfredo Corell
Your new post is loading...
Your new post is loading...
Scooped by Alfredo Corell
Scoop.it!

Innate immunity in vertebrates: an overview - Riera Romo - 2016 - Immunology - Wiley Online Library

Innate immunity is a semi-specific and widely distributed form of immunity, which represents the first line of defence against pathogens. 

Alfredo Corell's insight:

Innate immunity is a semi-specific and widely distributed form of immunity, which represents the first line of defence against pathogens. This type of immunity is critical to maintain homeostasis and prevent microbe invasion, eliminating a great variety of pathogens and contributing with the activation of the adaptive immune response. The components of innate immunity include physical and chemical barriers, humoral and cell-mediated components, which are present in all jawed vertebrates. The understanding of innate defence mechanisms in non-mammalian vertebrates is the key to comprehend the general picture of vertebrate innate immunity and its evolutionary history. This is also essential for the identification of new molecules with applications in immunopharmacology and immunotherapy. In this review, we describe and discuss the main elements of vertebrate innate immunity, presenting core findings in this field and identifying areas that need further investigation.

more...
No comment yet.
Scooped by Alfredo Corell
Scoop.it!

ScienceDirect.com - Developmental & Comparative Immunology - Maternal immunity in fish

ScienceDirect.com - Developmental & Comparative Immunology - Maternal immunity in fish | Immunology for University Students | Scoop.it

Both innate and adaptive immune-relevant factors are transferred from mother to offspring in fishes. These maternally-transferred factors include IgM, lysozymes, lectin, cathelicidin and complement components. Recently, yolk proteins, phosvitin and lipovitellin, have been shown to be maternally-transferred factors, functioning in the defense of teleost larvae against pathogens. Among these factors, the mode of action of complement components and yolk proteins has been explored, whereas that of all the other factors remains elusive. At present, the transfer mechanisms of maternally-derived immune factors are largely unknown although those of IgM and yolk protein transmission from mother to offspring have been reported in some fishes. Maternal transfer of immunity is affected by many elements, including biological factors, such as age and maturation, and environmental conditions experienced by brood fish, such as pathogens and nutritional supply. Practically, the manipulation of maternal immunity transfer can be used to enhance the survival rate of fish larvae.

Alfredo Corell's insight:
Maternal immunity in fishShicui Zhanga, , ,Zhiping Wangb,Hongmiao Wangaa Institute of Evolution and Marine Biodiversity and Department of Marine Biology, Ocean University of China, Qingdao 266003, Chinab Department of Life Science, Weinan Teachers University, Weinan 714000, China

http://dx.doi.org/10.1016/j.dci.2012.02.009,

more...
No comment yet.
Scooped by Alfredo Corell
Scoop.it!

Teaching the Relevance of Evolution to Understanding Immune Recognition

Teaching the Relevance of Evolution to Understanding Immune Recognition | Immunology for University Students | Scoop.it

This is a crucial step to understand the vast diversity of Immune specific receptors.

Alfredo Corell's insight:

Neil Greenspan Website http://www.case.edu/med/pathology/faculty/greenspan.html ;

more...
No comment yet.