Immunology for University Students
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Immunology for University Students
Resources and Material for Lecturers and Students - Immunology (University level)
Curated by Alfredo Corell
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AN INFECTIOUS DISEASES CARD GAME: MICROMANIA (British Society for Immunology)

AN INFECTIOUS DISEASES CARD GAME: MICROMANIA (British Society for Immunology) | Immunology for University Students | Scoop.it

RT @hjhope: BSI Summer School 2013 for PhD students & junior postdocs, 29 July-1 August at Newcastle University http://t.co/wjKBJt4O #immunology

Alfredo Corell's insight:

LINK TO THE GAME: http://www.immunology.org/page.aspx?pid=1844

 

To request a pack please email Sarah Green: s.green@immunology.org

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Immune Attack | Free teaching tool using a video game

Immune Attack | Free teaching tool using a video game | Immunology for University Students | Scoop.it

Navigate a nanobot through a 3D environment of blood vessels and connective tissue in an attempt to save an ailing patient. Teach white blood cells how to hunt and kill bacterial invaders. Along the way, you will learn about the biological processes that enable macrophages and neutrophils to detect and fight infections.

Alfredo Corell's insight:

A wonderful idea to use video games supporting lecturing.

 

This game is free, works on Windows XP and all later versions, install the latest version of Microsoft DirectX before playing. Not available for MacOS.

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Immunology Handwritten Tutorials - Videos

Immunology Handwritten Tutorials - Videos | Immunology for University Students | Scoop.it

Via Denis Hudrisier
Alfredo Corell's insight:

Good Immunology video-animations by handwritten tutorials. Sometimes a bit slow, sometimes a bit boring... but still very good; clear and basic immunology concepts.

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Denis Hudrisier's comment, December 14, 2012 4:48 AM
Very good animations on the immune system!
Denis Hudrisier's comment, December 14, 2012 4:51 AM
Niveau L3/M1. Davantage scientifiquement correct que les animations d'Armandohasudungan mais rythme un peu lent et commentaires un peu mornes. Très utiles néanmoins!
Denis Hudrisier's curator insight, July 23, 4:49 AM
Another nice and useful series of videos (including immunology)
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Cholesterol boosts the memory of the immune system

Cholesterol boosts the memory of the immune system | Immunology for University Students | Scoop.it
The memory of the human immune system is critical for the development of vaccines.
Alfredo Corell's insight:

The memory of the human immune system is critical for the development of vaccines. Only if the body recognizes a pathogen with which it has already come into contact in the case of a second infection, the immune system can combat it more effectively than it did the first time. The Freiburg immunobiologist Prof. Dr. Wolfgang Schamel from the Institute of Biology III of the University of Freiburg and his colleagues have succeeded in demonstrating how the memory of the immune system functions. Their findings have now been published in the journals Immunity and Journal of Biological Chemistry (JBC).


Direct Link to the JBC paper:

http://www.jbc.org/search?author1=Molnar+E&fulltext=&pubdate_year=&volume=&firstpage=&submit=yes


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ScienceDirect.com - Developmental & Comparative Immunology - Maternal immunity in fish

ScienceDirect.com - Developmental & Comparative Immunology - Maternal immunity in fish | Immunology for University Students | Scoop.it

Both innate and adaptive immune-relevant factors are transferred from mother to offspring in fishes. These maternally-transferred factors include IgM, lysozymes, lectin, cathelicidin and complement components. Recently, yolk proteins, phosvitin and lipovitellin, have been shown to be maternally-transferred factors, functioning in the defense of teleost larvae against pathogens. Among these factors, the mode of action of complement components and yolk proteins has been explored, whereas that of all the other factors remains elusive. At present, the transfer mechanisms of maternally-derived immune factors are largely unknown although those of IgM and yolk protein transmission from mother to offspring have been reported in some fishes. Maternal transfer of immunity is affected by many elements, including biological factors, such as age and maturation, and environmental conditions experienced by brood fish, such as pathogens and nutritional supply. Practically, the manipulation of maternal immunity transfer can be used to enhance the survival rate of fish larvae.

Alfredo Corell's insight:
Maternal immunity in fishShicui Zhanga, , ,Zhiping Wangb,Hongmiao Wangaa Institute of Evolution and Marine Biodiversity and Department of Marine Biology, Ocean University of China, Qingdao 266003, Chinab Department of Life Science, Weinan Teachers University, Weinan 714000, China

http://dx.doi.org/10.1016/j.dci.2012.02.009,

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History of Medical Discoveries: a "must" visit for any Student in Medicine or Biology

History of Medical Discoveries: a "must" visit for any Student in Medicine or Biology | Immunology for University Students | Scoop.it
Explore an interactive timeline of the history of medical discoveries and modern medicine.  Each medical image links to historical medical information and articles published in NEJM.
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Diphteria vaccine in 1913,

Spanish Influenza Pandemic 1918

.... and so on.... to our days

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WEB ADVENTURES: FOR STUDENTS — Explore Science and Medicine - One Game At A Time

WEB ADVENTURES: FOR STUDENTS — Explore Science and Medicine - One Game At A Time | Immunology for University Students | Scoop.it

MEDMYST is a collection of games to learn Science.

Some of the games are also available in Spanish:

http://webadventures.rice.edu/stu/Games/Espanol.html

 

Some games have mobile applications:

http://webadventures.rice.edu/stu/Games/Mobile-Applications/Germ-Blaster/

 

"MedMyst was a wonderful experience. Especially when you're trying to pursue a medical career.

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LiveScience #infographics gallery

LiveScience #infographics gallery | Immunology for University Students | Scoop.it
LiveScience infographics gallery...

 

Check out:

http://www.livescience.com/infographics/

 


Via Gust MEES
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Pepper Jay's curator insight, November 22, 2014 2:28 PM

I find LiveScience.com most interesting!

Pepper Jay

Actors Reporter / Actors Entertainment / Actors Radio

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Immunology SUMMARY VIDEO: Innate Immunity (Complement System Overview)

Overview of the Complement System and the pathways involved and their relationship with each other.

http://www.facebook.com/ArmandoHasudungan
Image: https://docs.google.com/open?id=0B8Ss3-wJfHrpQXZYLVNtNG9YME0

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Immunology VIDEO - Antibody Somatic (VDJ) Recombination II

Part II of the VDJ recombination video by  Armando Hasudungan

 

http://www.facebook.com/ArmandoHasudungan...

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How Salmonella inactivates the immune system

How Salmonella inactivates the immune system | Immunology for University Students | Scoop.it

Science 16 November 2012:
Vol. 338 no. 6109 pp. 963-967
DOI: 10.1126/science.1227037

Report

Salmonella Inhibits Retrograde Trafficking of Mannose-6-Phosphate Receptors and Lysosome Function

Kieran McGourty1,Teresa L. Thurston1,Sophie A. Matthews1,Laurie Pinaud1,*,Luís Jaime Mota1,†,David W. Holden1,‡

 

 

Salmonella enterica is an intracellular bacterial pathogen that replicates within membrane-bound vacuoles through the action of effector proteins translocated into host cells. Salmonella vacuoles have characteristics of lysosomes but are reduced in hydrolytic enzymes transported by mannose-6-phosphate receptors (MPRs). We found that the effector SifA subverted Rab9-dependent retrograde trafficking of MPRs, thereby attenuating lysosome function. This required binding of SifA to its host cell target SKIP/PLEKHM2. Furthermore, SKIP regulated retrograde trafficking of MPRs in noninfected cells. Translocated SifA formed a stable complex with SKIP and Rab9 in infected cells. Sequestration of Rab9 by SifA-SKIP accounted for the effect of SifA on MPR transport and lysosome function. Growth of Salmonella increased in cells with reduced lysosomal activity and decreased in cells with higher lysosomal activity. These results suggest that Salmonella vacuoles undergo fusion with lysosomes whose potency has been reduced by SifA.

 

The new in Science Daily:

http://www.sciencedaily.com/releases/2012/11/121115141510.htm?goback=.gde_2370476_member_186426014

 

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Ashley Morrison's comment, August 13, 2013 12:38 PM
What are the precautions for avoiding such illnesses???
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Immunology general Introductory Lecture (video) at University of Hawaïï

By Dr. Steven Farmer

Get the notes (if you pay for them) at

http://www.lulu.com/product/paperback/phrm-203/16453879
The lecture notes for this and all numbered lectures are available at Lulu.com, keyword PHRM203 or just follow the link. The notes do NOT include Exam Reviews, Paramedic Pharm, Heart Sounds, or Chest Tubes.

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Signal transduction and adhesion molecules - Course materials WKU - Claire Rinehart

Signal transduction and adhesion molecules - Course materials WKU - Claire Rinehart | Immunology for University Students | Scoop.it

All general explanations (and more) about Adhesion Molecules in the Course of Advanced Molecular Genetics-Biology 566, Western Kentucky University

 

Author: claire.rinehart@wku.edu

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Wikidoc - the living textbook of Medicine

Wikidoc - the living textbook of Medicine | Immunology for University Students | Scoop.it

Search Wiki Doc The Living Textbook of Medicine:

Alfredo Corell's insight:

WikiDoc is an open source website that allows an international community of healthcare professionals to add and edit medical content in a process termed co-creation.

 

The immunology part is still not too much developed; direct link:

http://www.wikidoc.org/index.php/Immunology

 

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The collection of YouTube Immuno-videos by Armando Faigil - a Fab visit

The collection of  YouTube Immuno-videos by Armando Faigil - a Fab visit | Immunology for University Students | Scoop.it
Buenos Dias, mi nombre es Armando Faigl. tady je muj channel.
Kono channel, iroiro na bideo ga aru. Videos which I hope can help students studying nursing, biomed, medicine, biology or any similar fields.

Via Denis Hudrisier
Alfredo Corell's insight:

More interesting that the handwritten tutorials, more quick and useful. I'm expecting the next release :)

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Denis Hudrisier's comment, December 14, 2012 4:48 AM
Excellent animations on the immune system! Well structured, dynamic: a must watch!
Denis Hudrisier's comment, December 14, 2012 4:50 AM
Niveau L3/M1. Le plus souvent scientifiquement correct. Plus dynamique que le "Handwritten tutorials"
Denis Hudrisier's curator insight, July 23, 4:47 AM
Very useful immunology videos assembled by Armando.
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Natural killer cells help to tolerate fetus during pregnacy by regulating inflammatory TH17 cells at the maternal-fetal interface

Natural killer cells help to tolerate fetus during pregnacy by regulating inflammatory TH17 cells at the maternal-fetal interface | Immunology for University Students | Scoop.it
Alfredo Corell's insight:
Binqing Fua,Xianchang Lib,c,Rui Suna,Xianhong Tongd,Bin Lingd,Zhigang Tiana,1, andHaiming Weia,1

 

Natural killer (NK) cells accumulate at the maternal–fetal interface in large numbers, but their exact roles in successful pregnancy remain poorly defined. Here, we provide evidence that TH17 cells and local inflammation can occur at the maternal–fetal interface during natural allogenic pregnancies. We found that decidual NK cells promote immune tolerance and successful pregnancy by dampening inflammatory TH17 cells via IFN-γ secreted by the CD56brightCD27+ NK subset. This NK-cell–mediated regulatory response is lost in patients who experience recurrent spontaneous abortions, which results in a prominent TH17 response and extensive local inflammation. This local inflammatory response further affects the regulatory function of NK cells, leading to the eventual loss of maternal-fetal tolerance. Thus, our data identify NK cells as key regulatory cells at the maternal–fetal interface by suppressing TH17-mediated local inflammation.

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Seminario sobre Defensinas

Trabajo de los alumnos de Inmunología General (2006-2007) de la UVa
Alfredo Corell's insight:

Resumen simple y directo de lo básico (estructura, función, asociación a enfermedad) de las defensinas. Elaborado por alumnos bajo mi tutela.

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Mechanisms of peripheral tolerance to allergens

Mechanisms of peripheral tolerance to allergens | Immunology for University Students | Scoop.it
Mechanisms of peripheral tolerance to allergensO. U. Soyer1,2,3,M. Akdis2,3,J. Ring3,4,H. Behrendt3,5,R. Crameri2,R. Lauener3,6,C. A. Akdis2,3,*

Article first published online: 18 DEC 2012

DOI: 10.1111/all.12085

Alfredo Corell's insight:

The immune system is regulated to protect the host from exaggerated stimulatory signals establishing a state of tolerance in healthy individuals. The disequilibrium in immune regulatory vs effector mechanisms results in allergic or autoimmune disorders in genetically predisposed subjects under certain environmental conditions. As demonstrated in allergen-specific immunotherapy and in the healthy immune response to high-dose allergen exposure models in humans, T regulatory cells are essential in the suppression of Th2-mediated inflammation, maintenance of immune tolerance, induction of the two suppressive cytokines interleukin-10 and transforming growth factor-β, inhibition of allergen-specific IgE, and enhancement of IgG4 and IgA. Also, suppression of dendritic cells, mast cells, and eosinophils contributes to the construction of peripheral tolerance to allergens. This review focuses on mechanisms of peripheral tolerance to allergens with special emphasis on recent developments in the area of immune regulation.

 

Link to the pdf file:

http://onlinelibrary.wiley.com/doi/10.1111/all.12085/pdf

 

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The Immunoblog-on-line

The Immunoblog-on-line | Immunology for University Students | Scoop.it

IMMUNOLOGY is a fascinating discipline of biology that studies the defenses of our body (humans, animals in general and even plants) against MICROBES (see also art blog on microbes).
The term "Immunology" comes from the latin word immunitas (exemption chore, exemption from service, remission etc..) and must be understood here as a dispense from infectious diseases.


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Fat's Immune Sentinels | The Scientist Magazine®

Fat's Immune Sentinels | The Scientist Magazine® | Immunology for University Students | Scoop.it

Fat's Immune Sentinels

Certain immune cells keep adipose tissue in check by helping to define normal and abnormal physiological states.

By Justin Odegaard and Ajay Chawla | December 1, 2012

 

Obesity and associated health consequences are the greatest public-health challenges of our time. Worldwide, an estimated 1.5 billion people tip the scales as overweight—300–500 million of whom are obese—placing nearly a quarter of humanity at dramatically increased risk for diabetes, cardiovascular disease, and many types of cancer. While considerable scientific investments have barely begun to slow the expansion of our waistlines, they have yielded unexpected physiologic insights, perhaps the greatest of which is the discovery that proper metabolic function requires a previously unsuspected level of cooperation between the cells that make up each internal organ and that organ’s resident leukocytes.

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Sky Sirewest's curator insight, November 15, 2013 2:38 AM

100-300lbs Weight -Loss Video & how they did it! 

http://healthtips180.isagenix.com/us/en/isavideos_100lb.dhtml


Isa body Challenge Video 

http://healthtips180.isagenix.com/us/en/video_isabody_challenge.dhtml


Athletes Results Video

http://healthtips180.isagenix.com/us/en/isavideos_athletes.dhtml ;


INTERACTIVE VIDEO   wow! this one is fun! http://apps.hustream.com/isagenix/revealed/ Weight Loss Stories "live" rec. 559 670 1425  For assistance call 240 374 2639  Bon-voyage!


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The Science of Immunisation: questions and answers - AAS simple and informative brochure

The Science of Immunisation: questions and answers - AAS simple and informative brochure | Immunology for University Students | Scoop.it

The Science of Immunisation: questions and answers

 

This publication aims to address confusion created by contradictory information in the public domain. It sets out to explain the current situation in immunisation science, including where there is consensus in the scientific community and where uncertainties exist.

 

The document is structured around six questions:

1 What is immunisation?

2 What is in a vaccine?

3 Who benefits from vaccines?

4 Are vaccines safe?

5 How are vaccines shown to be safe?

6 What does the future hold for vaccination?

 

The Science of Immunisation: Questions and Answers was prepared by a Working Group of eight members, co-chaired by Professors Tony Basten AO FAA FTSE and Ian Frazer AC FAA FRS FTSE. The document was also reviewed by an Oversight Committee chaired by Sir Gus Nossal AO CBE FAA FRS FTSE.

 

Link to de low resolution booklet:

http://www.science.org.au/policy/documents/AAS_Immunisation_FINAL_LR_v3.pdf

 

Link to the high resolution booklet:

http://www.science.org.au/policy/documents/AAS_Immunisation_FINAL_HR_v3.pdf

 

 

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Immunology VIDEO - Adaptive Immunity (B cell Hypermutation and Class Switching Overview)

A novel video by Armando Hasudungan:

 

http://www.facebook.com/ArmandoHasudungan...

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Immunology video - Antibody Somatic (VDJ) Recombination I

A new video by Armando Hasudungan

 

Immunology - Antibody Somatic (VDJ) Recombination Antibody Production http://www.facebook.com/ArmandoHasudungan...

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A novel innate ANTIBIOTIC discovered in animal cells. Potential therapeutic role if demonstrated in humans

A novel innate ANTIBIOTIC discovered in animal cells. Potential therapeutic role if demonstrated in humans | Immunology for University Students | Scoop.it

A novel role for lipid droplets in the organismal antibacterial response

Preetha Anand,1,† Silvia Cermelli,1,† Zhihuan Li,2 Adam Kassan,3 Marta Bosch,3 Robilyn Sigua,1 Lan Huang,1,4 Andre J Ouellette,5 Albert Pol,3,6 Michael A Welte,2 and Steven P Gross1,*

 

We previously discovered histones bound to cytosolic lipid droplets (LDs); here we show that this forms a cellular antibacterial defense system. Sequestered on droplets under normal conditions, in the presence of bacterial lipopolysaccharide (LPS) or lipoteichoic acid (LTA), histones are released from the droplets and kill bacteria efficiently in vitro. Droplet-bound histones also function in vivo: when injected into Drosophila embryos lacking droplet-bound histones, bacteria grow rapidly. In contrast, bacteria injected into embryos with droplet-bound histones die. Embryos with droplet-bound histones displayed more than a fourfold survival advantage when challenged with four different bacterial species. Our data suggests that this intracellular antibacterial defense system may function in adult flies, and also potentially in mice.

DOI: http://dx.doi.org/10.7554/eLife.00003.001

 

News in Science Daily:

http://www.sciencedaily.com/releases/2012/11/121113143656.htm?goback=.gde_2370476_member_185641076

 

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Immunology Webnotes at Wenny's Immunology syte

Immunology Webnotes at Wenny's Immunology syte | Immunology for University Students | Scoop.it

Immunology Webnotes by Wenlian Zhang,

University of Georgia

wenliang@uga.edu

 

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