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Las inmunopíldoras superan las 110.000 visitas con un promedio de 450 visitas diarias

Las inmunopíldoras superan las 110.000 visitas con un promedio de 450 visitas diarias | Immunology for University Students | Scoop.it
Píldoras de conocimiento de la asignatura "INMUNOLOGÍA HUMANA"
Profesor: Alfredo Corell Almuzara.
Alfredo Corell's insight:

La colección ha superado las 110.000 visitas totales, y la píldora 11.1 de introducción al sistema de complemento ha superado las 14.000 reproducciones.


La reproducción media es de 450 visitas diarias desde lugares como México, Perú, Colombia, Argentina, Rusia y por supuesto España (Valladolid, Cadiz, Granada, León entre otros). Gracias a todos, por vuestras visitas, vuestro apoyo y vuestros "me gusta".

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Denis Hudrisier's curator insight, May 16, 2014 4:47 AM

A remarkable work done by Alfredo Corell for the teaching of immunology!

Denis Hudrisier's curator insight, May 16, 2014 4:48 AM

Des cours d'immunologie en vidéo bien faites (en espagnol pour le moment)

Immunology for University Students
Resources and Material for Lecturers and Students - Immunology (University level)
Curated by Alfredo Corell
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INMUNOMEDIA 3.0 en la Aventura del Saber

En este video se muestra le entrevista que me han hecho en la Aventura del Saber y que se ha emitido el 5 de febrero de 2014

Alfredo Corell's insight:

Enlace al programa completo en rtve: http://www.rtve.es/alacarta/videos/la-aventura-del-saber/aventura-del-saber-05-02-14/2377592/ 


Enlace al videoclip de la entrevista en rtve a la carta: http://www.rtve.es/alacarta/videos/la-aventura-del-saber/aventura-del-saber-alfredo-corell/2374403/

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Nuria Parra Macías's curator insight, February 8, 2014 3:24 AM

Inmunomedia 3.0: una pica en Flandes en innovación docente. El ejemplo de flipped classroom de la facultad de Medicina de la universidad de Valladolid.

Nuria Parra Macías's comment, February 9, 2014 4:06 PM
A ti por la iniciativa :-)
Alfredo Corell's comment, February 12, 2014 3:20 PM
Cualquier tipo de difusión entre personal docente afin es bienvenida, así que gracias de corazón!!1
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If helper T cells have nothing to help, they kill their host

If helper T cells have nothing to help, they kill their host | Immunology for University Students | Scoop.it
For vaccines, CD4+ T cells can spell trouble

The ideal vaccine elicits immune memory—either antibodies or memory T cells—to protect the host from subsequent infections. T cell–mediated immunity requires both helper CD4+ T cells and cytotoxic CD8+ T cells to kill virus-infected cells. But what happens when a vaccine only elicits CD4+ memory T cells? Penaloza-MacMaster et al. probed this question by giving mice a vaccine that generated only memory CD4+ T cells against lymphocytic choriomeningitis virus (LCMV). Instead of protecting mice against chronic LCMV, vaccinated mice developed massive inflammation and died. Virus-specific CD8+ T cells or antibodies protected mice from the pathology. These results may have implications for vaccines against chronic viruses such as HIV.

Science 16 January 2015: 
Vol. 347 no. 6219 pp. 278-282 
DOI: 10.1126/science.aaa2148

Alfredo Corell's insight:

CD4 T cells promote innate and adaptive immune responses, but how vaccine-elicited CD4 T cells contribute to immune protection remains unclear. We evaluated whether induction of virus-specific CD4 T cells by vaccination would protect mice against infection with chronic lymphocytic choriomeningitis virus (LCMV). Immunization with vaccines that selectively induced CD4 T cell responses resulted in catastrophic inflammation and mortality after challenge with a persistent strain of LCMV. Immunopathology required antigen-specific CD4 T cells and was associated with a cytokine storm, generalized inflammation, and multi-organ system failure. Virus-specific CD8 T cells or antibodies abrogated the pathology. These data demonstrate that vaccine-elicited CD4 T cells in the absence of effective antiviral immune responses can trigger lethal immunopathology.

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Immunology: Fifty years of B lymphocytes

Immunology: Fifty years of B lymphocytes | Immunology for University Students | Scoop.it
Alexander D. Gitlin and Michel C.
Alfredo Corell's insight:

Alexander D. Gitlin and Michel C. Nussenzweig reflect on the discovery of two lineages of adaptive immune cells, and how it influenced vaccination, cancer therapy and the development of a class of antibody-based drugs.

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Las InmunoPíldoras alcanzan las 400.000 reproducciones en 15 meses

Las InmunoPíldoras alcanzan las 400.000 reproducciones en 15 meses | Immunology for University Students | Scoop.it

Desde este enlace se accede a la colección completa de Inmunopíldoras: 43 entregas hasta el momento

Alfredo Corell's insight:

En Enero de 2015 entregaremos al menos otras 10 píldoras de la sección de patología, para empezar el año con buen pié.

Estamos también preparando el subtitulado de las píldoras al inglés y al frandes... os iré informando.

Tengo que agradecer a todo el equipo técnico de la UVa y a los compañeros docentes de Valladolid, Madrid, Alicante y Toulouse su ayuda a que las píldoras sigan creciendo e internacionalizándose.

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Extreme Orange Allergy Nearly Kills Toddler in First Recorded Case

Extreme Orange Allergy Nearly Kills Toddler in First Recorded Case | Immunology for University Students | Scoop.it

Fruits like oranges don’t commonly cause allergic reactions, and even when they do, the symptoms are usually mild and involve irritation and itching of the mouth.No need to give up your morning glass of OJ, though.

Alfredo Corell's insight:

A 2-year-old girl in Pennsylvania nearly died recently after she suffered an unusually severe allergic reaction to eating an orange, her doctors reported.

The toddler picked up the orange in a supermarket, and within a few minutes of eating it, she developed a reaction that required a prompt trip to the emergency room, and later a helicopter ride to an intensive care unit at the Children's Hospital of Philadelphia.


other review at LiveScience: http://www.livescience.com/48636-this-girl-nearly-died-from-orange-allergy.html 

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In space, astronauts' immune systems get totally confused - Washington Post

In space, astronauts' immune systems get totally confused - Washington Post | Immunology for University Students | Scoop.it
Science Codex In space, astronauts' immune systems get totally confused Washington Post "If this situation persisted for longer deep space missions, it could possibly increase risk of infection, hypersensitivity, or autoimmune issues for...
Alfredo Corell's insight:

But it isn't certain that these changes would significantly increase the risks of long-term spaceflight. An upcoming year-long mission will provide further data for study. If the evidence suggests that immune system confusion could pose a threat to astronauts, the next step will be figuring out how to counteract it. Whatever they develop could make its way back to earth, providing new tools to help immune-compromised patients here at home.


Original Manuscript at the Journal of Interferon & Cytokine Research

DOI: 10.1089/jir.2013.0129

http://online.liebertpub.com/doi/pdf/10.1089/jir.2013.0129

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ImmuneQuest: engage your Immunology students with awesome online quizzes

ImmuneQuest: engage your Immunology students with awesome online quizzes | Immunology for University Students | Scoop.it
ImmuneQuest, a turn-based strategy game to learn immunology (@karencruzpelham If you haven't already, check out ImmuneQuest (http://t.co/nW4yjh4iUa). It's a 3D game that makes learning immunology...
Alfredo Corell's insight:
Get Started in Three Simple Steps:
1) Register your Course:

Click this link to register your course with ImmuneQuest. Register as many courses as you want.

2) Give students your course code so they can register:

Students register by opening ImmuneQuest, clicking "Students", and entering your course code.

3) View Class Metrics:

You can review the progress of all your registered students via the "metrics" link associated with each course code you've created below.

View Example Metrics

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¿Como funcionan los Anticuerpos? mi contribución en PechaKucha Night Valladolid vol.05 -

PechaKucha Night Valladolid volumen 5


¿Como funcionan los anticuerpos?

¿Cual ha sido mi camino en la Innovación Docente?

Alfredo Corell's insight:

Inmunología para todos los públicos 

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Immunology video-lecture: Toll Like Receptors Overview

I added a video to a @YouTube playlist http://t.co/jz3aWLHVGZ Immunology Toll Like Receptors Overview
Alfredo Corell's insight:

Another nice animation by Armando Hasudungan 

A summary about TLRs (Toll-like receptors)

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First Tests of Ebola Vaccine Appear at Least a Month Away - Bloomberg

First Tests of Ebola Vaccine Appear at Least a Month Away - Bloomberg | Immunology for University Students | Scoop.it
Bloomberg First Tests of Ebola Vaccine Appear at Least a Month Away Bloomberg It would be risky to perform initial safety trials of a Ebola vaccine in Africa where patients may be far from a good hospital that can provide modern medical care should...
Alfredo Corell's insight:

There is no cure for Ebola. The virus has killed 1,069 of 1,975 people afflicted in the four West African nations as of Aug. 11, the WHO said yesterday.

The disease is normally treated by keeping patients hydrated, replacing lost blood and using antibiotics to fight opportunistic infections. The hope is that a patient’s immune system will eventually fight off the virus’s aggressive attack.

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All Basic Immunology in 27 video - lectures UCIrvine ocw

All Basic Immunology in 27 video - lectures UCIrvine ocw | Immunology for University Students | Scoop.it
Antibodies, antigens, antigen-antibody reactions, cells and tissues of lymphoreticular and hematopoietic systems, and individual and collective components...
Alfredo Corell's insight:

You have here, on a row... al 27 basic immunology lectures, from introduction to final review.


Enjoy, while learning Immunology

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Immunomodulation by Gut Microbiota: Role of Toll-Like Receptor Expressed by T Cells

Immunomodulation by Gut Microbiota: Role of Toll-Like Receptor Expressed by T Cells http://t.co/ZTBwPJrLpH
Alfredo Corell's insight:

A close relationship exists between gut microbiota and immune responses. An imbalance of this relationship can determine local and systemic immune diseases. In fact the immune system plays an essential role in maintaining the homeostasis with the microbiota that normally resides in the gut, while, at the same time, the gut microbiota influences the immune system, modulating number and function of effector and regulatory T cells. To achieve this aim, mutual regulation between immune system and microbiota is achieved through several mechanisms, including the engagement of toll-like receptors (TLRs), pathogen-specific receptors expressed on numerous cell types. TLRs are able to recognize ligands from commensal or pathogen microbiota to maintain the tolerance or trigger the immune response. In this review, we summarize the latest evidences about the role of TLRs expressed in adaptive T cells, to understand how the immune system promotes intestinal homeostasis, fights invasion by pathogens, and is modulated by the intestinal microbiota.
Read more at http://ivancevichmd.blogspot.com/2014/07/immunomodulation-by-gut-microbiota-role.html#uJoxPLxwCzjbUuEo.99

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#CanalDefensas entrega 5: ANIMA TUS DEFENSAS - una sonrisa ayuda

Comparte tus vídeos con amigos, familia y el mundo.
Alfredo Corell's insight:

Más que nunca, poned una sonrisa. En esta estrega de Canal Defensas Esteban Sánchez, Becario Predoctoral en el IOBA y en InmunoLAB, en la Facultad de Medicina de Valladolid, nos va a contar cómo el estado de ánimo, el estrés o la euforia incluyen en nuestro sistema inmune. Así que "ANIMA TUS DEFENSAS".

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Inmunomedia 4.0 finalista en los Premios de la Cátedra de Educación Médica Fundación Lilly – UCM 2014

Inmunomedia 4.0 finalista en los Premios de la Cátedra de Educación Médica Fundación Lilly – UCM 2014 | Immunology for University Students | Scoop.it

Madrid, 20 de enero de 2015.- La Cátedra de Educación Médica Fundación Lilly-Universidad Complutense de Madrid (UCM) ha galardonado los proyectos presentados por el Centro Nacional de Investigaciones Cardiovasculares (CNIC) que dirige el doctor Valentín Fuster, y por el doctor Jordi Casademont, “Formación de posgrado en Investigación Cardiovascular” y “Situación actual de la enseñanza de la Patología General en España”, respectivamente, con sus Premios de Educación Médica 2014. El acto de entrega de los premios tendrá lugar el próximo día 29 de enero a las 19:00 horas en la Facultad de Medicina de la Universidad Complutense de Madrid.

Alfredo Corell's insight:

Además, la iniciativa “InmunoMedia 4.0: Enseñando y aprendiendo Inmunología”, basado en el uso de las nuevas tecnologías multimedia y las redes sociales para la docencia de esta especialidad, ha resultado finalista en la categoría de enseñanza de grado.

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El medio ambiente, y no los genes, dicta la variación inmunológica humana

El medio ambiente, y no los genes, dicta la variación inmunológica humana | Immunology for University Students | Scoop.it

Resumen de hallazgos en BITNAVEGANTES

El medio ambiente, y no los genes, dicta la variación inmunológica humana http://t.co/q8HqsaB6GE

Alfredo Corell's insight:
Variation in the Human Immune System Is Largely Driven by Non-Heritable Influences
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Animation: Immunology of the lung : Nature Immunology

Animation: Immunology of the lung : Nature Immunology | Immunology for University Students | Scoop.it
Nature Immunology is a multidisciplinary journal that publishes papers of the highest quality and significance in all areas of immunology. Priority is given to work that provides fundamental insight into the workings of the immune system. Areas covered include, but are not limited to, innate immunity and inflammation; development; immune receptors, signaling and apoptosis; antigen presentation; gene regulation and recombination; cellular and systemic immunity; vaccines; immune tolerance; autoimmunity and tumor immunology, microbial immunopathology; and transplantation.
Alfredo Corell's insight:

Another impressive animation about mucosal immunology by The Nature jornal

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Why You Are Still Alive - The Immune System Explained - YouTube

Every second of your life you are under attack. Bacteria, viruses, spores and more living stuff wants to enter your body and use its resources for itself. Th...
Alfredo Corell's insight:

A very simple video to have an overview of the immune system functions.... have a look

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New comic book explains to children about Primary Immunodeficiency

New comic book explains to children about Primary Immunodeficiency | Immunology for University Students | Scoop.it
New comic book explains to children about Primary Immunodeficiency
News-Medical.net
Explaining the effects and lifestyle impact of PID to a child can be very challenging for families, especially during times of anxiety and stress around diagnosis.
Alfredo Corell's insight:

the book will cost 14,45 USD


link to the book shop: http://shop.medikidz.com/products/medikidz-explain-primary-immunodeficiency

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a video overview on B lymphocytes (B cells)

Overview of B cells (B lymphocytes) and how they are activated and produce antibodies (#Immunology - Overview of B cells (B lymphocytes) and how they are activated and produce antibodies http://t.co/3WRtkI1Vq4...
Alfredo Corell's insight:

another video lecture from Khan academy,this time about the basic facts of B-cells

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Educational module about the immune system and regenarative medicine

Educational module about the immune system and regenarative medicine | Immunology for University Students | Scoop.it

The Immunology team of the Entertainment Technology Center at Carnegie Mellon University aims to design an educational module about the immune system and regenerative medicine.

Alfredo Corell's insight:

This project is in collaboration with Duquesne University. To make this experience both fun and informative, the team is creating a simulation/strategy style video game employing video and real time technologies.

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250.000 visitas en las Inmunopíldoras: estudiantes universitarios de Colombia, Méjico y España los más activos

250.000 visitas en las Inmunopíldoras: estudiantes universitarios de Colombia, Méjico y España los más activos | Immunology for University Students | Scoop.it
Píldoras de conocimiento de la asignatura "INMUNOLOGÍA HUMANA" Profesor: Alfredo Corell Almuzara.
Alfredo Corell's insight:

Se han superado, justo 1 año tras su lanzamiento inicial, las 250.000 visitas a las Inmunopíldoras (píldoras de conocimiento de Inmunología).


Las visitas proceden de estudiantes de diferentes nacionalidades (los países con más visitas son Colombia, Méjico y España).


Os recuerdo que se han lanzado recientemente píldoras de carácter divulgativo (CANAL DEFENSAS): https://www.youtube.com/watch?v=FIBt1z5vbjw&list=PLSbo9kXA_LczFn2uGvkAti9lFBDmeUKZw


Gracias a todos por el apoyo, y en especial a los alumnos de todo el mundo que me escriben comentando sobre el proyecto.

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Influence of the microbiota on vaccine effectiveness

Influence of the microbiota on vaccine effectiveness | Immunology for University Students | Scoop.it
Publication stage: In Press Corrected Proof
Alfredo Corell's insight:


Highlights


  • Gut microbial composition affects immune system function.
  • The immune system influences host microbial populations.
  • Microbiota diversity and composition may impact upon vaccine efficacy.
  • A mechanistic understanding should inform future vaccination strategies.



Studies of the relationship between the microbiome and the development and function of the immune system are demonstrating novel concepts that could significantly alter the way we treat disease and promote wellness. Several diseases, including inflammatory bowel disease, allergy/asthma, and diabetes, are associated with changes in composition of the microbiome. Recent findings suggest novel complex mechanisms by which the microbiome impacts immune cell development and differentiation. A major implication of these findings is that the composition of microbiome may ultimately affect vaccine efficacy. We explore here the potential role of the microbiome in vaccine responses in the context of our growing understanding of the relationship between the gastrointestinal microbiota, resident immune cell populations, and systemic immunity.

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#PKNVA mi presentación completa en PechaKucha Night Valladolid vol.05 sobre Anticuerpos

#PKNVA mi presentación completa en PechaKucha Night Valladolid vol.05 sobre Anticuerpos | Immunology for University Students | Scoop.it

20 diapositivas x 20 segundos:

400 segundos hablando al público asistente cómo son los anticuerpos y explicando porqué son tan importantes en nuestra vida

Alfredo Corell's insight:
MUCHAS GRACIAS A TODOS POR VUESTRA ASISTENCIA
  • Se usan para determinar el grupo sanguíneo
  • Se usan para realizar el test de embarazo
  • Cuando nos ponen la anti-tetánica... ahí hay anticuerpos
  • Cuando se dice que alguien es "seropositivo", es porque hay anticuerpos
  • etc...
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Alfredo Corell's curator insight, August 5, 2014 3:00 PM
MUCHAS GRACIAS A TODOS POR VUESTRA ASISTENCIA
  • Se usan para determinar el grupo sanguíneo
  • Se usan para realizar el test de embarazo
  • Cuando nos ponen la anti-tetánica... ahí hay anticuerpos
  • Cuando se dice que alguien es "seropositivo", es porque hay anticuerpos
  • etc...
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Dendritic cells, monocytes and macrophages: a unified nomenclature based on ontogeny.

Dendritic cells, monocytes and macrophages: a unified nomenclature based on ontogeny. | Immunology for University Students | Scoop.it
Nature Reviews Immunology 14571–578 (2014)
 
doi:10.1038/nri3712 - Published online 18 July 2014
Alfredo Corell's insight:

ABSTRACT: The mononuclear phagocyte system (MPS) has historically been categorized into monocytes, dendritic cells and macrophages on the basis of functional and phenotypical characteristics. However, considering that these characteristics are often overlapping, the distinction between and classification of these cell types has been challenging. In this Opinion article, we propose a unified nomenclature for the MPS. We suggest that these cells can be classified primarily by their ontogeny and secondarily by their location, function and phenotype. We believe that this system permits a more robust classification during both steady-state and inflammatory conditions, with the benefit of spanning different tissues and across species.

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Color atlas of immunology - free e-book in slideshare - 2003 edition

Immunology_Atlas

Alfredo Corell's insight:

Be careful, this slideshare version is an old 2003 edition. Thus, some novel findings in the fast growing field of Immunology may not be included

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Las defensas se "alían" con la web 3.0

Las defensas se "alían" con la web 3.0 | Immunology for University Students | Scoop.it

Reflexiones sobre el proyecto Inmunomedia 3.0 en el suplemento Innovadores de "El Mundo".

Alfredo Corell's insight:

No tengo por menos que agradecer a todos los que estáis ahí al otro lado (cerca o lejos, como profesores, estudiantes o amigos). El impacto de Inmunomedia (Canal Defensas e Inmunopíldoras) es cada vez mayor.


Canal Defensas: https://www.youtube.com/playlist?list=PLSbo9kXA_LczFn2uGvkAti9lFBDmeUKZw 


Inmunopíldoras: https://www.youtube.com/playlist?list=PLSbo9kXA_Lcwc1ouBQcafihsdvEmW2dng


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