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Rescooped by Eugene Ch'ng from Complex Insight - Understanding our world
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What's quantum physics got to do with biology?

Tonight at the World Science Festival, astrophysicist Paul Davies and quantum computing innovator Seth Lloyd will talk about the growing field of quantum biology—why it works, what it means, and how it might shape our future. The Bad News: The Festival is happening in New York City and tonight's panel is sold out. The Good News: You can watch a live webcast of the event online at 8:00 Eastern time.  Learn more


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Rescooped by Eugene Ch'ng from Complex Insight - Understanding our world
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Bacterial signaling systems as platforms for rational design of new generations of biosensors

Bacterial signaling systems as platforms for rational design of new generations of biosensors

by
Checa SK, Zurbriggen MD, Soncini FC.
"Bacterial signal-responsive regulatory circuits have been employed as platform to design and construct whole-cell bacterial biosensors for reporting toxicity. A new generation of biosensors with improved performance and a wide application range has emerged after the application of synthetic biology concepts to biosensor design. Site-directed mutagenesis, directed evolution and domain swapping were applied to upgrade signal detection or to create novel sensor modules. Rewiring of the genetic circuits allows improving the determinations and reduces the heterogeneity of the response between individual reporter cells. Moreover, the assembly of natural or engineered modules to biosensor platforms provides innovative outputs, expanding the range of application of these devises, from monitoring toxics and bioremediation to killing targeted cells."
http://1.usa.gov/JTBbQj


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