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Informatics towards Precision Medicine
Informatics aspects of Precision Medicine
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MOOM-Massive Open On line Medical information.

MOOM-Massive Open On line Medical information. | Informatics towards Precision Medicine | Scoop.it

The article entitle  "Individualize medicine from prewomb to tomb"     (http://www.cell.com/cell/fulltext/S0092-8674%2814%2900204-9 ) explain the new term “precision medicine” as defined by “tailoring of medical treatment to the individual characteristics of each patient”. This require multiple layers of data: biosensors, scanners, electronic medical records, social media, and the various omics that include DNA sequence, transcriptome, proteome, metabolome, epigenome, microbiome, and exposome.

From the integrated personal omics profiling (iPOP) or “Snyderome,” we are focus on the use of a biosensor watch to passively collect data that could make diagnosis at the earliest possible time, avoiding any end-organ damage or use the panoromic information, coupled with biosensors that track air quality, pollution, forced expiratory volume, and other relevant physiologic metrics, could prove useful to prevent an attack.

Furthermore we have the BLOOD ON CONTINOUS SURVEILLANCE by using injectable nanosensors to detect a DNA, RNA, autoantibody, or protein signal and to wirelessly transmit the signal to the individual’s Smartphone. This are the microfluidic electrochemical detector for in vivo continuous monitoring (MEDIC) (http://stm.sciencemag.org/content/5/213/213ra165.short )

By taking the deidentified data from each individual, including panoromic, biosensors, social graph, treatment, and outcomes allows massive open online medical information (MOOM) repositories that could provide matching capability to approximate a newly diagnosed individual’s data as compared with all of those previously amalgamated.


Via Unesco Telemedicine
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Unesco Telemedicine's curator insight, April 4, 2:56 AM

We have to collect not only personal data but environement data in home care to assure prevention, follow up treatment, improvement of quality of life, and should be stored in two repositories, one for the patient itself control and treatment, but one anonimous for MOOM analysis.

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Researchers Create Database of CNVs in Healthy Individuals - BioArray News

Researchers Create Database of CNVs in Healthy Individuals - BioArray News | Informatics towards Precision Medicine | Scoop.it
A team of scientists from CHOP and UPenn have developed a database of copy number variants found in healthy individuals, based on their study of thousands of children and parents.
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Developing Tools for Discovery & Implementation in Personalized Medicine - Dan Roden, M.D.

Dr. Roden received his medical degree and training in internal medicine from McGill University in Montreal and trained in clinical pharmacology and cardiology at Vanderbilt University, where...
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UConn Health Doctors Working on Personalized Ovarian Cancer Vaccine - NBC Connecticut

UConn Health Doctors Working on Personalized Ovarian Cancer Vaccine - NBC Connecticut | Informatics towards Precision Medicine | Scoop.it
For the first time ever, doctors and scientists at UConn Health hope to use state of the art genetic information to make personalized vaccines for women with ovarian cancer.
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CDC - Blogs - Genomics and Health Impact Blog – Nobody is average but what to do about it? The challenge of individualized disease prevention based on genomics

CDC - Blogs - Genomics and Health Impact Blog – Nobody is average but what to do about it? The challenge of individualized disease prevention based on genomics | Informatics towards Precision Medicine | Scoop.it
CDC - Blogs - Genomics and Health Impact Blog – Nobody is average but what to do about it?
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Tracking Genomic Cancer Evolution for Precision Medicine: The Lung TRACERx Study

Tracking Genomic Cancer Evolution for Precision Medicine: The Lung TRACERx Study | Informatics towards Precision Medicine | Scoop.it
PLOS Biology is an open-access, peer-reviewed journal that features works of exceptional significance in all areas of biological science, from molecules to ecosystems, including works at the interface with other disciplines.
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What is ‘precision medicine’? | Genetic Literacy Project

What is ‘precision medicine’? | Genetic Literacy Project | Informatics towards Precision Medicine | Scoop.it
“The future of precision medicine means every patient will have treatments and prevention tailored to his or her genes and environmental exposures from before (The skinny on 'precision medicine' by @ksenapathy Kavin Senapathy”
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UCSF Informatics Day 2014 - Keith R. Yamamoto, "Precision Medicine"

“Keith R.Yamamoto, PhD — Opening Remarks – Precision Medicine Vice Chancellor for Research Executive Vice Dean of the School of Medicine Professor of Cellular … (Precision medicine brings together data analysis, research, science”
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The microeconomics of personalized medicine | McKinsey & Company

The microeconomics of personalized medicine | McKinsey & Company | Informatics towards Precision Medicine | Scoop.it
“Personalized medicine promises to increase the quality of clinical care and, in some cases, to decrease health care costs. The biggest hurdles are economic, not scientific. A McKinsey & Company article.”
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Making the Case for Personalized Medicine | BIO...

Making the Case for Personalized Medicine | BIO... | Informatics towards Precision Medicine | Scoop.it
“Personalized medicine is the customization of healthcare. Already, a suite of molecular approaches is being used to tailor certain medical decisions, practice.”
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Washington Post: The triumph of genomic medicine is just beginning

Washington Post: The triumph of genomic medicine is just beginning | Informatics towards Precision Medicine | Scoop.it
“SOURCE March 13, 2014: Washington Post “A Decade Later, Genetic Map Yields Few New Cures,” said a New York Times headline in June 2010.”
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Aging contributes to rapid rates of genomic change, signaling challenges for personalized medicine | Virginia Tech News | Virginia Tech

Aging contributes to rapid rates of genomic change, signaling challenges for personalized medicine | Virginia Tech News | Virginia Tech | Informatics towards Precision Medicine | Scoop.it
Virginia Bioinformatics Institute researchers have found that genomes age differently across populations and within individuals, making personalized medicine more challenging than was previously thought.
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Optimizing Oncology Clinical Trials with Person...

Optimizing Oncology Clinical Trials with Person... | Informatics towards Precision Medicine | Scoop.it
“Personalized medicine is the art and science of “coupling established clinical–pathological indexes with state-of-the-art molecular profiling to create diagnostic, prognostic and therapeutic strategies precisely tailored to each patient’s...”
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Home | PACBB'15 | International Conference on Practical Applications of Computational Biology & Bioinformatics

Home | PACBB'15 | International Conference on Practical Applications of Computational Biology & Bioinformatics | Informatics towards Precision Medicine | Scoop.it
9th International Conference on Practical Applications of Computational Biology & Bioinformatics, Organized by BISITE Reseach Group of University of Salamanca; 3rd-5th June, 2015, Salamanca (Spain)
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New interdisciplinary center at MIT to focus on the microbiome and human health - MIT News

New interdisciplinary center at MIT to focus on the microbiome and human health - MIT News | Informatics towards Precision Medicine | Scoop.it
Partnership with MGH, other institutions to foster regional ecosystem for rapidly evolving field.
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Patients to benefit from new £5m MRC Regional Phenome Centre at Birmingham - Birmingham - NewsLocker

Patients to benefit from new £5m MRC Regional Phenome Centre at Birmingham - Birmingham - NewsLocker | Informatics towards Precision Medicine | Scoop.it
The University of Birmingham has announced plans to establish a £5m MRC Regional Phenome Centre (RPC), which will help to improve the health of patients through novel research and technology.
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The Precision Medicine Approach at WCMC Explained

The Precision Medicine Approach at WCMC Explained | Informatics towards Precision Medicine | Scoop.it
In a recent article from the The Magazine of Weill Cornell Medical College and Weill Cornell Graduate School of Medical Sciences, physicians and scientists from the Lymphoma Program explained their...
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Diseases, symptoms, genes, and proteins linked together in giant network - Medical Xpress

Diseases, symptoms, genes, and proteins linked together in giant network - Medical Xpress | Informatics towards Precision Medicine | Scoop.it
Medical Xpress Diseases, symptoms, genes, and proteins linked together in giant network Medical Xpress The HSDN definitely boosts the translational medicine and precision medicine field, where the data source can be used to identify the clinical...
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How Personalized Medicine Is Changing: Breast Cancer

How Personalized Medicine Is Changing: Breast Cancer | Informatics towards Precision Medicine | Scoop.it
“ In 2011, a 52-year-old runner and yoga enthusiast walked into the office of Monica Loghin, a neuro-oncologist at MD Anderson Cancer Center in Houston, complaining … (RT @GenomeMag: “There used to be just a few cancer drugs.”
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Principles and clinical applications of next-generation DNA sequencing

“Technologies for sequencing DNA have improved dramatically, to the point that it has become practical to sequence an individual’s entire genome.”
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New report offers a primer for doctors' use of clinical genome and exome sequencing

“Leading scientists have sketched out what doctors need to know in order to use the new technology effectively.”
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Muir Gray: Population based and personalised care—two sides of the same coin

Muir Gray: Population based and personalised care—two sides of the same coin | Informatics towards Precision Medicine | Scoop.it
“Health services have become archipelagos. There are great islands like primary care and secondary care, acute and community, or public healt (RT @DrKhouryCDC: Population & individualized medicine: 2 sides of the same coin.”
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Genomics|Update|Current | Precision Medicine Daily

Genomics|Update|Current | Precision Medicine Daily | Informatics towards Precision Medicine | Scoop.it
“The mission of CDC's Public Health Genomics is to integrate advances in human genetics into public health research, policy, and programs (RT @DrKhouryCDC: Personalized medicine in a #genomic era #pm101 #EBM still needs a population perspective (Genomics|Update|Current...”
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Team reduces the size of the human genome to 19,000 genes

Team reduces the size of the human genome to 19,000 genes | Informatics towards Precision Medicine | Scoop.it
“How nutrients are metabolised and how neurons communicate in the brain are just some of the messages coded by the 3 billion letters that make up the human genome.”
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Aging contributes to rapid rates of genomic change, signaling challenges for personalized medicine | Virginia Tech News | Virginia Tech

Aging contributes to rapid rates of genomic change, signaling challenges for personalized medicine | Virginia Tech News | Virginia Tech | Informatics towards Precision Medicine | Scoop.it
Virginia Bioinformatics Institute researchers have found that genomes age differently across populations and within individuals, making personalized medicine more challenging than was previously thought.
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Personalized medicine in psychiatry: problems a...

Personalized medicine in psychiatry: problems a... | Informatics towards Precision Medicine | Scoop.it
“The central theme of personalized medicine is the premise that an individual’s unique physiologic characteristics play a significant role in both disease vulnerability and in response to specific therapies.”
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