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Our findings suggest that HEV genotype 3 infections are widespread in the English population and in blood donors. Transfusion-transmitted infections rarely caused acute morbidity, but in some immunosuppressed patients became persistent. Although at present blood donations are not screened, an agreed policy is needed for the identification of patients with persistent HEV infection, irrespective of origin, so that they can be offered antiviral therapy.FundingPublic Health England and National Health Service Blood and Transplant.
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The Lancet, Early Online Publication, 28 July 2014doi:10.1016/S0140-6736(14)61034-5Cite or Link Using DOI Copyright © 2014 Hewitt et al. Open Access article distributed under the terms of CC BY-NC-ND Published by Elsevier Ltd. All rights reserved.Hepatitis E virus in blood components: a prevalence and transmission study in southeast EnglandPatricia E Hewitt FRCPath a, Samreen Ijaz PhD b, Su R Brailsford PhD a c, Rachel Brett BSc a, Steven Dicks MSc a b, Becky Haywood BSc b, Iain T R Kennedy MFPH c, Alan Kitchen PhD a, Poorvi Patel MSc a b, John Poh PhD b, Katherine Russell MFPH c,Kate I Tettmar MBA a b, Joanne Tossell RN a, Ines Ushiro-Lumb FRCPath a b, Prof Richard S Tedder FRCPath a b d