A*STAR researchers show that dermal dendritic cells migrate to the site of a sterile injury in a highly directed manner, independent of blood neutrophil migration
When skin is injured or exposed to a pathogen attack, the body’s immune system responds rapidly. But the exact skin-cell-based mechanisms behind these responses remain unclear. Now, A*STAR researchers have uncovered how skin-localized cells calleddermal dendritic cells (DDCs) respond to sterile skin injuries1. Their insights may help to develop new therapeutic interventions administered via the skin, and define the role of skin immune cells in autoimmune and metabolic diseases.
Via Krishan Maggon