Immunology and Biotherapies
13.0K views | +6 today
Follow
Immunology and Biotherapies
Page Ressources et Actualités du DIU immunologie et biothérapies
Your new post is loading...
Your new post is loading...
Rescooped by Gilbert C FAURE from Top Selling Monoclonal Antibodies 2014
Scoop.it!

Side effects of Immune System Drugs: Cytokines and Monoclonal Antibodies

Side effects of Immune System Drugs: Cytokines and Monoclonal Antibodies | Immunology and Biotherapies | Scoop.it
Abstract

This review of the July 2013 to December 2014 publications on cytokines and monoclonal antibodies covers bone morphogenic proteins, colony-stimulating factors, interferons, interleukins, tumor necrosis factor alfa, adalimumab, certolizumab, etanercept, golimumab, infliximab, abciximab, alemtuzumab, bevacizumab, cetuximab, daclizumab, natalizumab, ranibizumab, rituximab, tocilizumab and trastuzumab.

 

KeywordsAdverse reactions; Cytokines; Monoclonal antibodies; Bone morphogenic proteins;Colony-stimulating factors; Interferons; Interleukins; Tumor necrosis factor alfa;Adalimumab; Certolizumab; Etanercept; Golimumab; Infliximab; Abciximab;Alemtuzumab; Bevacizumab; Cetuximab; Daclizumab; Natalizumab; Ranibizumab;Rituximab; Tocilizumab; Trastuzumab


Via Krishan Maggon
more...
Krishan Maggon 's curator insight, October 10, 2015 8:43 AM
Side Effects of Drugs Annual

Available online 1 October 2015

In Press, Corrected Proof — Note to users

 
Drugs That Act on the Immune System: Cytokines and Monoclonal AntibodiesLokesh K. Jha*, Sandeep Mukherjee†, , 
 
 
 
doi:10.1016/bs.seda.2015.08.006
Rescooped by Gilbert C FAURE from Top Selling Monoclonal Antibodies 2014
Scoop.it!

Best Selling Monoclonal Antibodies 2013

Best Selling Monoclonal Antibodies 2013 | Immunology and Biotherapies | Scoop.it

Via Krishan Maggon
Gilbert C FAURE's insight:

impressive for immunologists so far away from so big amounts of money

more...
Krishan Maggon 's curator insight, January 6, 2014 8:38 AM

Abstract

 

A review of the best selling monoclonal antibodies in 2013 and 2012 is provided. Humira with sales of over $11 billion ($9.3 billion in 2012) remains the best selling monoclonal antibody, biologic as well prescription drug brand in 2013 as in 2012. The ranks of the next 4 top selling mabs remained unchanged from the 2012 Table.  Remicade (9.7 Bn), Rituxan (7.5 Bn) , Herceptin (6.5 Bn) and Avastin (6.5 Bn) were the second, third, fourth and fifth top selling mabs in 2013. The actual sales for 2013 as reported by the companies are provided. The total sales of the top selling blockbuster mabs were $63 billion in 2013. The actual global sales of all the approved blockbuster sales or potential (sales >1 billion) monoclonal antibodies in 2013 is provided. Besides the top 5 mabs, there were 2 other monoclonal antibodies with sales of over 2 billion dollars and 5 with sales of over $ 1 billion in 2013. In addition 5 recently launched mabs were nearing to reach sales of $ 1 billion this year. Currently 30 monoclonal antibodies are marketed in the US and Europe (January 2014).  Alexion Soliris was the most expansive marketed monoclonal antibody with a price tag of $440,000 per year of treatment, a sort of Rolls-Royce of mabs.