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AbstractMigraine remedies have been studied by Mehdi et al with particular emphasis on Ginger. Their studies evaluated the efficacy of ginger in comparison to sumatriptan therapy. In this double-b...
The effect of neem leaf extract on c-Myc oncogene expression was studied. An oncogene is a gene that, when mutated or expressed at high levels, helps turn a normal cell into a tumor cell. The purpo...
Alternative therapies against lethal pancreatic cancer (PC) are continually being sought. Shimizu et al indentified Holy Basil (Ocimum sanctum) as a potential candidate for cancer therapy. Holy Bas...
Ginger and Heart Health [6]-Gingerol derived from Ginger (Zingiber officinale Roscoe) was identified as a novel angiotensin II type 1 receptor antagonist. Angiotensins are a group of ...
Jittiwat & Wattanathorn have demonstrated that ginger could potentially improve memory impairment following cerebral ischemia. Using Ginger and pharmacopuncture, in combination, in an induced...
As we have seen before Liquorice components can be beneficial to health. Glycyrrhizin is a main component of liquorice and has shown various immunomodulatory activities that can interfere with immu...
Citronberg et al studied the effects of Ginger on apoptosis, proliferation, and differentiation in the normal-appearing colonic mucosa using a randomized approach. They measured expression and di...
Two types of Ginger were investigated for a component – 1′-acetoxychavicol acetate (ACA) – which is naturally obtained from Ginger rhizomes and seeds. Ginger is noted for its anti...
Five widely studied medicinal plants derived from botanical sources [Bacopa monniera, Silybum marianum (milk thistle), Withania somnifera (Ashwagandha), Camellia sinensis (Green Tea), and Curcuma longa (turmeric)] have been shown to activate Nrf2 and induce phase II enzymes through the antioxidant response element. In a study by Reuland et al determined the antioxidant treatments of the above natural herbal plants on cardiomyocytes. These phytochemical treatments were associated with nuclear accumulation of Nrf2, significant induction of phase II enzymes, and concomitant protection against hydrogen peroxide-induced apoptosis. The protection against oxidant stress was abolished when Nrf2 was silenced by shRNA, suggesting that the natural antioxidants work through the Nrf2 pathway. They conclude that natural antioxidants like Green Tea are a potential treatment to increase antioxidant defenses and protect heart cells against an oxidative challenge.
Alqahtani et al, from the University of Sydney, studied Pentacyclic triterpenoids – compounds found in various herbal plants like Glycyrrhiza species (Liquorice), Centella asiatica, Camellia sinensis (Green Tea) amongst others. These plants are used in traditional medicines like Ayurveda and are known to be effecient in the treatment of diabetes and diabetic complications.
Cinnamon extract were administrated and serum levels of TNF-alpha and interleukin (IL)-6 were determined 1 hour after Lipopolysaccharide stimulation. Various biomarkers were assayed for viability, cytokine expression and signaling molecules upon stimulation. Liposaccharides act as endotoxins and elicit strong immune responses in animals. RESULTS: The results show that oral administration of cinnamon in an animal model system significantly decreased the serum levels of TNF-alpha and IL-6. CWE treatment in vitro decreased the mRNA expression of TNF-alpha. The scientist conclude that treatment with cinnamon extract decreased LPS-induced TNF-alpha in serum and the results indicate that the observed anti-inflammatory action of Cinnamon extract may originate from the presence of polyphenols.
Results indicated that the Neem glycoprotein induces proliferation of mononuclear cells amongst other immunological changes and could induce an anti-tumor immune environment that results in the restriction of carcinoma growth. The investigators conclude that accumulated evidence strongly suggests the non-toxic nature of the Neem glycoprotein and could be recommended for human use in anti-cancer therapy.
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Glycyrrhizic acid (GA) is a bioactive ingredient of licorice (Glycyrrhiza glabra), and has been found to be associated with multiple therapeutic properties. In a study by Ma et al they investigated...
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Green Tea and Ginger have both been investigated recently in terms of their ability to positively affect obesity. An investigation by Mahmoud & Elnour was conducted to evaluate the effect of gi...
Ayurvedic Tea and Herbs Infusions for Relaxing, Sleeping, Energy, Stamina, Diet, Slimming, Weight Management, Anti Ageing, Memory
Licochalcone is a component of liquorice and seems to have promising antimalarial activity. In continuation of a drug discovery program by Tadigoppula et al they isolated two chalcones & synthe...
Beauty products to help you overcome the January blues.
Glucocorticoids are often used as treatments for inflammatory diseases, such as asthma and chronic obstructive pulmonary disease. Patients however are suffering from glucocorticoid resistance and t...
Albarracin et al, have done a nice review of polyphenols with antioxidant properties which are abundant in the diet. Fruits, vegetables, herbs, and various drinks (infusions etc) are sources of the...
Ayurvedic Tea and Herbs Infusions for Relaxing, Sleeping, Energy, Stamina, Diet, Slimming, Weight Management, Anti Ageing, Memory. One way to limit this glucose spike could be to inhibit the activity of digestive enzymes for glucose production and of the transporters responsible for glucose absorption. It looks like Flavonols, Theaflavins, Gallate esters, 5-caffeoylqunic acid and proanthocyanidins inhibit α-amylase activity. Amylase is the enxyme that breaks down more complex sugars into glucose and maltose. Recent results also suggest that plant polyphenolics like those found in Green Tea could help in this respect. Anthocyanidins and catechin oxidation products, such as theaflavins and theasinsensins, inhibit maltase; sucrase is less strongly inhibited but anthocyanidins seem somewhat effective. Lactase is inhibited by Green Tea catechins.
Tsai et al investigated the in vivo antioxidant and antifibrotic properties of Green Tea(Camellia sinensis) with induced oxidative stress and hepatic fibrosis in an animal model study. Results suggest that Green Tea exhibits powerful protective effects against induced oxidative stress and hepatic fibrosis in an animal model system by inhibiting oxidative damage and increasing antioxidant enzyme activities.
Ginger has been demonstrated to lower triglycerides or fats but its mechanisms remain unclear. Recent evidence has suggested that Fructose overconsumption is associated with increase in fat deposit. In this study by Gao et al found that extracts of ginger (in an animal study) over 5 weeks reversed liquid fructose-induced increase in plasma triglyceride and glucose concentrations and hepatic triglyceride content. Hypertriglyceridemia (hTG), a condition in which triglyceride levels are elevated, is a common disorder in the United States. It is often caused or exacerbated by uncontrolled diabetes mellitus, obesity, and sedentary habits, all of which are more prevalent in industrialized societies than in developing nations. In epidemiologic and interventional studies, hypertriglyceridemia is a risk factor for coronary artery disease (CAD). Medscape The study suggests that Ginger can ameliorate of fructose-induced fatty liver and hypertriglyceridemia. They suggest that this modulation occurs due to the hepatic ChREBP-mediated pathway.
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