A study by Souza et al was made on Carvone a component of Mint. (-)-Carvone is a monoterpene found in Mint essential oil.
In this study (-)-carvone anti-spasmodic effect was investigated in animal model system. The effect of (-)-carvone was compared with that of the classical calcium channel blocker verapamil.
Carvone reduced the contractions induced and was almost 100 times more potent than verapamil.
In conclusion (-)-carvone showed a typical and potent calcium channel blocker action. The effects described for both (-)-carvone and mint can be explained as a calcium channel blocker mode of action.