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Media, News & Topics on prevention, diagnosis & treatment of cardiovascular disease
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Blood Thinners: JAMA patient page

Blood Thinners: JAMA patient page | Heart and Vascular Health | Scoop.it

There are 2 types of blood thinners, anticoagulants and antiplatelet drugs. Blood clots can cause problems when they prevent blood from flowing freely, especially to the heart and brain. Sometimes a doctor may not want a patient’s blood to clot as easily and will prescribe a blood thinner.

Seth Bilazarian, MD's insight:

Nice graphic that helps patients understand the differences between antiplatelet & anticoagulant therapy. This is an important source of confusion for patient's who believe that aspirin is an effective therapy for stroke prevention in atrial fibrillation (it is not).  Another potential confusion is why blood thinners or anticoagulants like warfarin or the newer agents (Pradaxa, Xarelto, Eliquis) are not effective treatments after placement of a stent in the coronary artery. Antiplatelet therapies like Plavix, Effient, or Brilinta are needed.

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Deborah Verran's curator insight, May 18, 1:56 AM

This is a good example of the type of reliable factual online information that is available to patients. Some transplant recipients will end up having to take these types of medications (for the appropriate indications). Hence the importance of this particular information.

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How to Get the Best Price on New Generic Plavix (updated Feb 2013)

How to Get the Best Price on New Generic Plavix (updated Feb 2013) | Heart and Vascular Health | Scoop.it

Price Update as of October 2012: Cost Per Pill
When we queried the large pharmacy providers five months ago, we were told that after a few months competition would set in and prices should drop significantly. Our survey on October 4, 2012 showed only a very small dip in prices. So much for free market competition!

For 75 mg generic clopidogrel, both CVS and Walgreens were quoting slightly more than $5.50 a pill, only an 8% drop from May. WalMart/Sam's Club was offering generic clopidogrel in their in-store pharmacies for approximately $1.80 per pill; $1.50 if you ordered from their centralized home delivery.

But once again, the price winner was Costco. Their cash price is now $0.32 a pill, or under $10 a month!

Worthy of note: Brand-name Plavix is now selling for $7.50/pill at Walgreen's, a significant rise from the pre-generic era. In fact, Walgreen's current generic price of $5.50 is slightly more than the brand-name price was before the drug went generic.

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FDA Approves Generic Versions of Plavix

FDA Approves Generic Versions of Plavix | Heart and Vascular Health | Scoop.it

My comment for patients:  this will move Plavix in the form of clopidogrel to the generic tier for patients with substantial savings on copayments.  For cash paying patients the cost should descend quickly from nearly 200/;month to less than 50 / month in the next 6 months because of the number of competitors.  To check the price at a pharmacy near you see my scoop it below.  Massachusetts Drug Card or go to link

https://reportal.restat.com/xpertrx/drugPrices

 

The price at my local pharmacy tfor 1 month on 5/19/2012 via this look up was $160.76 

 

Generic Plavix (Clopidogrel) approved by the FDA: Nine pharmaceutical companies will produce 2 different generic versions of the ubiquitous blood thinner. 

On the FDA website: Generic drugs approved by FDA are of the same high quality and strength as brand-name drugs. The generic manufacturing and packaging sites must pass the same quality standards as those for brand-name drugs. http://goo.gl/3oAWQ  ;

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Spending on Basic Prescriptions Decreases

Spending on Basic Prescriptions Decreases | Heart and Vascular Health | Scoop.it
Spending on basic prescription drugs like cholesterol-lowering pills recorded a rare decline in the U.S.

The slight decrease in traditional-drug spending reflected Express Scripts's success in steering members toward cheaper pills and new generic versions of major drugs like Pfizer Inc.'s cholesterol drug Lipitor and Bristol-Myers Squibb Co.'s anticlotting drug Plavix.

Drugs for inflammatory conditions like rheumatoid arthritis made up the costliest specialty category last year, Express Scripts said, with spending up 23%. This category includes the blockbuster drug Humira from Abbott Laboratories spinoff AbbVie, which posted $9.27 billion in sales last year, a 17% rise.

The liver disease hepatitis C was another area where Express Scripts saw soaring spending—up 33.7%—following the 2011 approval of new drugs from Vertex Pharmaceuticals Inc. and Merck & Co. Express Scripts expects spending in this area, where prescriptions cost nearly $3,300 per month for commercially insured members, to continue growing rapidly.


Seth Bilazarian, MD's insight:

The availability of generic version of Lipitor (Atorvastatin) and Plavix (clopidogrel) has been a huge benefit to patients.  Out of pocket costs have declined since these drugs are now available in the lowest tier on pharmacy benefit plans.  There is no significant cardiovascular drug on the near horizon which will have patent expiration so this savings is not likely to be seen again for a long time.  The NOACs (Pradaxa, Xarelto, Eliquis) will cause significant increase in spending in the next several years to offset these savings.

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How to Get the Best Price on Generic Plavix from Angioplasty.Org

How to Get the Best Price on Generic Plavix from Angioplasty.Org | Heart and Vascular Health | Scoop.it

Key Takeaway:  When generic drugs first become available the market is dynamic.  With Plavix there are 7 manufacturers and pharmacies have not all priced in the expected discount.  This excellent service by angioplasty.org evaluated and found a range from 35 cents to 17 times greater.  For those paying cash the critical message is SHOP!

 

At the Mass Drug look up http://www.madrugcard.com/ ; on 5/31/2012 CVS lists 30 day supply $154.05 and Walgreens $179.32.

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