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Media, News & Topics on prevention, diagnosis & treatment of cardiovascular disease
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Obesity: consensus statement from National Lipid Association

Obesity: consensus statement from National Lipid Association | Heart and Vascular Health | Scoop.it

Adiposopathy: simplified relationship between pathogenic adipose tissue and cardiovascular disease. Adiposopathy is promoted by unhealthy nutrition and a sedentary lifestyle in genetically and environmentally predisposed individuals. With impaired adipogenesis of peripheral, subcutaneous adipose tissue during positive caloric balance, existing fat cells may hypertrophy, circulating free fatty acids may increase, and lipids may be deposited in nonadipose tissue organs (eg, liver, muscle, possibly pancreas) resulting in lipotoxicity. Adiposopathic endocrine and immune responses may be directly pathogenic to the cardiovascular system or otherwise interact with other body systems. If not mitigated by these other body organs, adiposopathy may indirectly cause or promote major atherosclerotic risk factors 

Seth Bilazarian, MD's insight:

A complex relationship made simple by realizing that the top is all that you need to know about preventing the hazards of obesity related medical illness.

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Sprinting, Not Jogging, Sheds More Belly Fat,

Sprinting, Not Jogging, Sheds More Belly Fat, | Heart and Vascular Health | Scoop.it

Sprinting, not jogging, helps men lose harmful belly fat faster.  Eight-second bursts of sprinting on an exercise bike repeated intermittently for 20 minutes, 3 times per week,  helped overweight men lose 4 pounds of body fat over 12 weeks.

My comment: this data contradicts previous data supporting the notion that longer duration not higher intensity exercise is more efficient & effective at weight loss.  The sprinting described was part of a 2o minute exercise program (8 s sprint, 12 s recovery).  Interestingly the investigators had subjects sprint to achieve a heart rate which was 80 - 90% of their maximum predicted heart rate, which would qualify as higher but not highest intensity exercise.

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Relation Between Optimism and Lipids in Midlife

Relation Between Optimism and Lipids in Midlife | Heart and Vascular Health | Scoop.it

The hypothesis that optimism is associated with a healthier lipid profile was tested. The participants were 990 mostly white men and women from the Midlife in the United States study, who were, on average, 55 years old.  Models examined the cross-sectional association between optimism and lipid levels, accounting for education and health status (e.g., chronic medical conditions).

After adjustment the results suggested that greater optimism was associated with greater HDL cholesterol and lower triglycerides. Optimism was not associated with low-density lipoprotein or total cholesterol. The findings were robust to a variety of modeling strategies including the effect of cholesterol treatment. The results also indicated that diet and body mass index might link optimism with lipids.

This is the first study to suggest that optimism is associated with a healthy lipid profile; moreover, these associations can be explained, in part, by the presence of healthier behaviors and a lower body mass index.

Seth Bilazarian, MD's insight:

The associations were small but clinically significant. The optimism effect is similar in size to the effect of physical activity.  From the paper, "optimism might serve as a precursor to healthy behavior by motivating " behavior for favorable expectations of the future.

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