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High aerobic fitness in late adolescence is associated with reduced risk of heart attack

High aerobic fitness in late adolescence is associated with reduced risk of heart attack | Heart and Vascular Health | Scoop.it

Aims Cardiovascular disease is the leading cause of morbidity and mortality worldwide, and signs of atherosclerosis are present in all large arteries already in adolescence. We investigated the association between high physical fitness in late adolescence and myocardial infarction (MI) later in life.

Methods and results The study cohort comprised 743,498 Swedish men examined at the age of 18 years during conscription 1969–84. Aerobic fitness (Wmax) and muscle strength at conscription were measured. During follow-up period of 34 years, 11,526 MIs were registered in the cohort. After adjusting for age, body mass index (BMI), diseases, education, blood pressure, and socio-economic factors, one standard deviation increase in the level of physical fitness was associated with an 18% decreased risk of later MI.  The beneficial effects of Wmax were significant across all recognized BMI groups, ranging from lean (BMI < 18.5) to obese (BMI > 30) (P < 0.05 for all). However, obese men (BMI > 30) in the highest fourth of Wmax had a higher risk of MI than did lean men (BMI < 18.5) in the highest (HR 4.6, 95% CI 1.9–11.2), and lowest (HR 1.7, 95% CI 1.2–2.6) fourth of Wmax.

Conclusions We report a significant graded association between aerobic fitness in late adolescence and MI later in life in men. However, obese men with a high aerobic fitness had a higher risk of MI than lean men with a low aerobic fitness.

Seth Bilazarian, MD's insight:

The impact of overweight status and fitness status (both aerobic and strength) in 18 yo men,  predicted heart attack over the next 3 decades.  Although both are important, as can be seen in the graphic, the impact of overweight status (fatness) was of greater risk than being "unfit".  Fatness worse than unfitness.

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Jenny Han's curator insight, December 13, 5:55 AM

Graph shows what we should learn.

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Obesity May Hasten Cognitive Decline

Obesity May Hasten Cognitive Decline | Heart and Vascular Health | Scoop.it

People who are obese in middle age and who have high blood pressure and other so-called metabolic risk factors have a speedier cognitive decline as they get older than people of normal weight, according to a large study published Monday in the journal Neurology.

The study, involving 6,401 participants and spanning 10 years, adds to research indicating that obesity increases the risk of dementia later in life.

"In the last 10 years or so, people started suggesting you could be fit and fat—you could be obese and metabolically healthy and have no health risk," said Archana Singh-Manoux, lead author of the study and research director at Inserm, the French National Institute of Health and Medical Research.

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How much exercise is enough?

How much exercise is enough? | Heart and Vascular Health | Scoop.it

My comment: Here's the answer to the question => What's the least I have to do? Answer: the more you do the better.  Fitness & Fatness independently important.

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“We found that adding low amounts of physical activity to one’s daily routine, such as 75 minutes of brisk walking per week, was associated with increased longevity: a gain of 1.8 years of life expectancy after age 40, compared with doing no such activity"

We all know that exercise is good for you, but how good? While previous studies have shown the link between physical activity and a lower risk of premature mortality, the number of years of life expectancy gained among persons with different activity levels has been unclear — until now.

In a new study from Harvard-affiliated Brigham and Women’s Hospital (BWH), in collaboration with the National Cancer Institute, researchers have quantified how many years of life are gained by being physically active at different levels, among all individuals as well as among various groups having different body mass indexes (BMI).

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