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Facts About AFib & The Risk Of Stroke

Facts About AFib & The Risk Of Stroke | Heart and Vascular Health | Scoop.it

Atrial fibrillation (AFib), a type of irregular heartbeat, not caused by a heart valve problem affects approximately 5.8 million people in the U.S. – including me. AFib not caused by a heart valve problem puts people at a 5 times greater risk for stroke. It's why I'm challenging you now to learn the fibs and the facts about AFib-related stroke risk, and share them with everyone you care about.

Seth Bilazarian, MD's insight:

Good basic quiz providing info about  atrial fibrillation.  Fibs or Facts is an educational campaign from Bristol-Myers Squibb and Pfizer to help people learn the fibs and facts about AFib not caused by a heart valve problem and its associated increased risk of stroke.

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Donovan Baldwin's curator insight, December 4, 2013 9:19 AM

Having had my own AFib event, I found this interesting and informative.

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Warfarin in the Prevention of Stroke Associated with Nonrheumatic Atrial Fibrillation — NEJM

Warfarin in the Prevention of Stroke Associated with Nonrheumatic Atrial Fibrillation — NEJM | Heart and Vascular Health | Scoop.it

20 years ago today the SPINAF trial was published.  This was one of the last studies to compare warfarin to placebo in atrial fibrillation (Afib)  for the prevention of stroke.  For the lsat 20 years warfarin has been the standard of care.  Anticoagulants (blood thinners) prevent stroke in Afib.  After this there were only a few more studues that were done comparing warfarin to placebo or aspirin (SPAF-II in 1994)  because it was felt to not be ethical since the benefits of warfarin are so clear for stroke prevnetion.  

AIn teh US, we've had only warfarin (coumadin) until 2 years ago (10/2010) when the first of the novel oral anticoagulants (NOACs) were introduced.  Pradaxa (dabigatran) and Xarelto (rivaroxaban) are now available in the US.  We expext Eliquis (apixiban) in 2013 with others to follow.

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Eliquis: New Medication for Atrial Fibrillation

An in-depth conversation between Pentucket Medical cardiologists Seth Bilazarian and Sunny Srivastava, focusing on a newly released medicine to reduce the risks of atrial fibrillation. The latest among recently approved blood thinners, Eliquis joins Pradaxa and Xarelto as an alternative to Coumadin, a drug that has been in use since the 1950s. Like Pradaxa and Xarelto, Eliquis has been shown to reduce risk of stroke and bleeding, as well as mortality. All the new drugs eliminate the need for regular blood testing that Coumadin necessitates.

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Pradaxa (dabigatran) Safety Review of Serious Bleeding Events by FDA

UPDATED 11/02/2012. Results of FDAs Mini-Sentinel assessment indicate that bleeding rates associated with new use of Pradaxa do not appear to be higher than bleeding rates associated with new use of warfarin.
My comment -= I hope this review by the FDA reassures patients that the use of Pradaxa is safe as an alternative to warfarin,. This adds to the randomized trial RE-L. Patients are being unnecessarily frightened by TV ads by malpractice attorneys and decisions about options fro treatment are being complicated without reason.,
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