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Media, News & Topics on prevention, diagnosis & treatment of cardiovascular disease
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Scooped by Seth Bilazarian, MD
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Do Statins cause dementia?

Do Statins cause dementia? | Heart and Vascular Health | Scoop.it

Adults with no history of cognitive dysfunction treated with statins were included from high-quality randomized controlled trials and prospective cohort studies after formal bias assessment. Sixteen studies were included in qualitative & 11 in quantitative synthesis.

Short-term trials did not show a consistent effect of statin therapy on cognitive end points. Long-term cognition studies included 23,443 patients with a mean exposure duration of 3 to 24.9 years. Three studies found no association between statin use and incident dementia, and 5 found a favorable effect. Pooled results revealed a 29% reduction in incident dementia in statin-treated patients.

Conclusion In patients without baseline cognitive dysfunction, short-term data are most compatible with no adverse effect of statins on cognition, and long-term data may support a beneficial role for statins in the prevention of dementia.
Seth Bilazarian, MD's insight:

Patients are understandably concerned that a medicine might cause problems with their ability to think and function as they age.  For proponents  (like me) of statin type cholesterol lowering medicines the long-term benefit of improved vascular health provided by statins is compelling.  The theoretical benefit on long term brain health from improved vascular health is also interesting but conflicts with some reports taht memory might be effected by statin use.  The authors from Johns Hopkins have provided a useful review of the literature and concluded that statins are neutral to positive for long term brain health and function, and may "support a beneficial role for statins in the prevention of dementia".

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Scooped by Seth Bilazarian, MD
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Statin Usage - National Survey

Statin Usage - National Survey | Heart and Vascular Health | Scoop.it

Learn about statins and understand the risks of high cholesterol through the official Web resource for the USAGE Survey, the largest known cholesterol survey in the US (10,100 participants)

 

Key Findings
Survey participants were highly satisfied with the info provided to them about  cholesterol & its treatment with statins:
=> 85% USAGE participants consider their physician to be one of two most valuable resources for info
=>  53% USAGE participants use their physician as the sole source of information on statins

=>  Only about half of USAGE participants remember their cholesterol levels (knowing your numbers us correlated with treatment success)

=>  Only about half of USAGE participants remember receiving recommendations on diet & exercise at every doctor's office visit.

=>  one out of three USAGE participants had statin side effects andstopped medicine without first discussing the issue with their physician.

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