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Media, News & Topics on prevention, diagnosis & treatment of cardiovascular disease
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Scooped by Seth Bilazarian, MD
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Obesity: consensus statement from National Lipid Association

Obesity:  consensus statement from National Lipid Association | Heart and Vascular Health | Scoop.it

Inter-relationship between adiposopathy, type 2 diabetes mellitus, hypertension, dyslipidemia and atherosclerosis. FFA, free fatty acid; HDL, high-density lipoprotein; LDL, low-density lipoprotein.

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Scooped by Seth Bilazarian, MD
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Obesity: consensus statement from National Lipid Association

Obesity: consensus statement from National Lipid Association | Heart and Vascular Health | Scoop.it

Adiposopathy: simplified relationship between pathogenic adipose tissue and cardiovascular disease. Adiposopathy is promoted by unhealthy nutrition and a sedentary lifestyle in genetically and environmentally predisposed individuals. With impaired adipogenesis of peripheral, subcutaneous adipose tissue during positive caloric balance, existing fat cells may hypertrophy, circulating free fatty acids may increase, and lipids may be deposited in nonadipose tissue organs (eg, liver, muscle, possibly pancreas) resulting in lipotoxicity. Adiposopathic endocrine and immune responses may be directly pathogenic to the cardiovascular system or otherwise interact with other body systems. If not mitigated by these other body organs, adiposopathy may indirectly cause or promote major atherosclerotic risk factors 

Seth Bilazarian, MD's insight:

A complex relationship made simple by realizing that the top is all that you need to know about preventing the hazards of obesity related medical illness.

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