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AI app could help diagnose HIV more accurately

AI app could help diagnose HIV more accurately | healthcare technology | Scoop.it

More than 100 million HIV tests are performed around the world annually, meaning even a small improvement in quality assurance could impact the lives of millions of people by reducing the risk of false positives and negatives.

 

Academics from the London Center for Nanotechnology at UCL and AHRI used deep learning (artificial intelligence/AI) algorithms to improve health workers' ability to diagnose HIV using lateral flow tests in rural South Africa.

 

Their findings, published today in Nature Medicine, involve the first and largest study of field-acquired HIV test results, which have applied machine learning (AI) to help classify them as positive or negative.

 

By harnessing the potential of mobile phone sensors, cameras, processing power and data sharing capabilities, the team developed an app that can read test results from an image taken by end users on a mobile device. It may also be able to report results to public health systems for better data collection and ongoing care.

 

read the study at https://www.nature.com/articles/s41591-021-01384-9

 

 

read more at https://medicalxpress.com/news/2021-06-ai-app-hiv-accurately.html

 

nrip's insight:

The use of mobile tools for data capture and AI/ML algorithms for diagnostics and detections has been the inside story of digital health over the past 4 years. This is an excellent study and shows the promise of this combination of technologies in building the future of healthcare. HIV is a pandemic which must be eradicated.

Elizabeth Taylor's curator insight, March 8, 1:22 AM
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Algorithms begin to show practical use in diagnostic imaging

Algorithms begin to show practical use in diagnostic imaging | healthcare technology | Scoop.it

Algorithms based on machine learning and deep learning, intended for use in diagnostic imaging, are moving into the commercial pipeline.

 

However, providers will have to overcome multiple challenges to incorporate these tools into daily clinical workflows in radiology.

 

There now are numerous algorithms in various stages of development and in the FDA approval process, and experts believe that there could eventually be hundreds or even thousands of AI-based apps to improve the quality and efficiency of radiology.

 

The emerging applications based on machine learning and deep learning primarily involve algorithms to automate such processes in radiology as detecting abnormal structures in images, such as cancerous lesions and nodules. The technology can be used on a variety of modalities, such as CT scans and X-rays. The goal is to help radiologists more effectively detect and track the progression of diseases, giving them tools to enhance speed and accuracy, thus improving quality and reducing costs.

 

While the number of organizations incorporating these products into daily workflows is small today, experts expect many providers to adopt these solutions as the industry overcomes implementation challenges.

 

Data dump
Radiologists’ growing appreciation for AI may result from the technology’s promise to help the profession cope with an explosion in the amount of data for each patient case.

 

Radiologists also are grappling with the growth in data from sources outside radiology, such as lab tests or electronic medical records. This is another area where AI could help radiologists by analyzing data from disparate sources and pulling out key pieces of information for each case,.

 

There are other issues that AI could address as well, such as “observer fatigue,” which is an “aspect of radiology practice and a particular issue in screening examinations where the likelihood of finding a true positive is low,” wrote researchers from Massachusetts General Hospital and Harvard Medical School in a 2018 article in the Journal of the American College of Radiology.

 

These researchers foresee the utility of an AI program that could identify cases from routine screening exams with a likely positive result and prioritize those cases for radiologists’ attention.

AI software also could help radiologists improve worklists of cases in which referring physicians already suspect that a medical problem exists.

 

read more at the original source: https://www.healthdatamanagement.com/news/algorithms-begin-to-show-practical-use-in-diagnostic-imaging

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Intermountain researchers develop smartphone-based lab test for stress

Intermountain researchers develop smartphone-based lab test for stress | healthcare technology | Scoop.it

Researchers from Intermountain Healthcare have developed a smartphone-based test for measuring salivary cortisol, which can help care providers understand the patient’s stress levels. The test can be performed at the point of care in just five minutes.


When someone feels stress, their body’s natural response is to release hormones, including adrenaline and cortisol, to help them deal with the “threat”. When cortisol is released, it increases glucose in the system, but also curbs nonessential functions including the digestive system, the reproductive system and growth processes.


When people feel stress throughout the day, thus releasing too much cortisol, it can lead to anxiety, depression, digestive problems, heart disease, sleep problems, weight gain, and memory and concentration impairment.


To perform the test, care providers use a smartphone’s camera to take a picture using the flash. From there, the image analysis app can identify the user’s cortisol levels. 


“When cortisol levels are overlooked too many people suffer and die because of excess or insufficient cortisol,” lead researcher and Intermountain Medical Center Director of Diabetes and Endocrinology Dr. Joel Ehrenkranz said in a statement.


Ehrenkranz also believes this test will be especially helpful for people with diabetes.


more at http://mobihealthnews.com/34753/intermountain-researchers-develop-smartphone-based-lab-test-for-stress/



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Grant awarded to develop artificial intelligence to improve stroke screening and treatment in smaller hospitals

Grant awarded to develop artificial intelligence to improve stroke screening and treatment in smaller hospitals | healthcare technology | Scoop.it

New artificial intelligence technology that uses a common CT angiography (CTA), as opposed to the more advanced imaging normally required to help identify patients who could benefit from endovascular stroke therapy (EST), is being developed at The University of Texas Health Science Center at Houston (UTHealth).

 

Two UTHealth researchers worked together to create a machine-learning artificial intelligence tool that could be used for assessing a stroke at every hospital that takes care of stroke patients - not just at large academic hospitals in major cities. 

 

Research to further develop and test the technology tool is funded through a five-year, $2.5 million grant from the National Institutes of Health (NIH). 

 

"The vast majority of stroke patients don't show up at large hospitals, but in those smaller regional facilities. And most of the emphasis on screening techniques is only focused on the technologies used in those large academic centers. With this technology, we are looking to change that," said Sunil Sheth, MD, assistant professor of neurology at McGovern Medical School at UTHealth.

 

Sheth set out with Luca Giancardo, PhD, assistant professor with the Center for Precision Health at UTHealth School of Biomedical Informatics, to develop a quicker way to assess patients. The result was a novel deep neural network architecture that leverages brain symmetry. Using CTAs, which are more widely available, the system can determine the presence or absence of a large vessel occlusion and whether the amount of "at-risk" tissue is above or below the thresholds seen in those patients who benefitted from EST in the clinical trials.

 

"This is the first time a data set is being specifically collected aiming to address the lack of quality imaging available for stroke patients at smaller hospitals," Giancardo said.

 

read the complete press release with further details on the work at https://www.uth.edu/news/story.htm?id=9fccdefb-ff91-4775-a759-a786689956ea

 

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Run a single test to determine which viruses have infected an individual

Run a single test to determine which viruses have infected an individual | healthcare technology | Scoop.it

New technology developed by Howard Hughes Medical Institute (HHMI) researchers makes it possible to test for current and past infections with any known human virus by analyzing a single drop of a person's blood. The method, called VirScan, is an efficient alternative to existing diagnostics that test for specific viruses one at a time, according to the scientists.


With VirScan, researchers can run a single test to determine which viruses have infected an individual, rather than limiting their analysis to particular viruses.


That unbiased approach could uncover unexpected factors affecting individual patients' health, and also expands opportunities to analyze and compare viral infections in large populations. The analysis reportedly can be performed for about $25 per blood sample.

“We've developed a screening methodology to basically look back in time in people's sera and see what viruses they have experienced,” says Stephen J. Elledge, an HHMI investigator at Brigham and Women's Hospital who led an international team that developed VirScan. “Instead of testing for one individual virus at a time, which is labor intensive, we can assay all of these at once. It's one-stop shopping.”

VirScan works by screening the blood for antibodies against any of the 206 species of viruses known to infect humans. The immune system produces pathogen-specific antibodies when it encounters a virus for the first time, and it can continue to make those antibodies for years or decades after it clears an infection. That means VirScan not only identifies viral infections that the immune system is actively fighting, but also provides a history of an individual's past infections.


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