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Fragrance Chemicals & Health
This topic explore how air fresheners, scented cleaning products, scented laundry detergents, and perfumes may affect health.
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EHP – Formaldehyde and Epigenetic Alterations: MicroRNA Changes in the Nasal Epithelium of Nonhuman Primates

Background: Formaldehyde is an air pollutant present in both indoor and outdoor atmospheres. Because of its ubiquitous nature, it is imperative to understand the mechanisms underlying formaldehyde-induced toxicity and carcinogenicity. MicroRNAs (miRNAs) can influence disease caused by environmental exposures, yet miRNAs are understudied in relation to formaldehyde. Our previous investigation demonstrated that formaldehyde exposure in human lung cells caused disruptions in miRNA expression profiles in vitro. ...


Conclusions: Formaldehyde exposure significantly disrupts miRNA expression profiles within the nasal epithelium, and these alterations likely influence apoptosis signaling.

Environmental Illness Network Minnesota's insight:

According to the EPA (http://www.epa.gov/kidshometour/products/airf.htm), formaldehde is one of the four basic ingredients of air fresheners.

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Exposed: Cancer-Causing Toxins Found in Air Fresheners

"Here are some of the ingredients found in the popular metered air fresheners—you know, the ones that are battery-operated and pump out mists of supposed sanitizers several times an hour..."

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EHP – Formaldehyde and Epigenetic Alterations: MicroRNA Changes in the Nasal Epithelium of Nonhuman Primates

EHP – Formaldehyde and Epigenetic Alterations: MicroRNA Changes in the Nasal Epithelium of Nonhuman Primates | Fragrance Chemicals & Health | Scoop.it

"Conclusions: Our study reveals that formaldehyde exposure significantly disrupts miRNA expression profiles within the nasal epithelium, and these alterations likely influence apoptosis signaling."

Environmental Illness Network Minnesota's insight:

Formaldehyde is an ingredient in many "air fresheners."

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Cleaning products and air fresheners: emissions and resulting concentrations of glycol ethers and terpenoids. [Indoor Air. 2006] - PubMed - NCBI

While effective cleaning can improve the healthfulness of indoor environments, this work shows that use of some consumer cleaning agents can yield high levels of volatile organic compounds, including glycol ethers--which are regulated toxic air contaminants--and terpenes that can react with ozone to form a variety of secondary pollutants including formaldehyde and ultrafine particles.
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