Martin Karplus, the Theodore William Richards Professor of Chemistry Emeritus in Harvard's Department of Chemistry and Chemical Biology, is one of three to share in the Nobel Prize in chemistry, the The Royal Swedish Academy of Sciences announced...
Cancer cells feel a special appetite for a type of sugar called glucose, research demonstrated nearly a hundred years ago. The tumor uses glucose like a sports car uses gasoline -- it depends on it to burn faster, to grow and to multiply rapidly. In cancer cells, glucose superaccelerates cell division in what is known as the Warburg effect. New research shows that in one in four human tumors, there is an excess of glucose receptors in the external face of the cell membrane and this protein acts as a magnet attracting all the glucose from the bloodstream.
Digital Cameras present photographers with an ever increasing array of Automatic and Semi Automatic shooting modes. Most of these center around different ways of exposing your shots – however many cameras also give options for different focusing modes (auto, continuous focusing for moving subjects and manual). It’s no wonder then that many photographers never make …
Researchers have pinpointed why normal aging is accompanied by a diminished ability to regain strength and mobility after muscle injury: over time, stem cells within muscle tissues dedicated to repairing damage become less able to generate new muscle fibers and struggle to self-renew. Scientists identified for the first time a process by which the older muscle stem cell populations can be rejuvenated to function like younger cells.
The bacterial endophytic microbiome promotes plant growth and health and beneficial effects are in many cases mediated and characterized by metabolic interactions. Recent advances have been made in regard to metabolite production by plant microsymbionts showing that they may produce a range of different types of metabolites. These substances play a role in defense and competition, but may also be needed for specific interaction and communication with the plant host. Furthermore, few examples of bilateral metabolite production are known and endophytes may modulate plant metabolite synthesis as well. We have just started to understand such metabolic interactions between plants and endophytes, however, further research is needed to more efficiently make use of beneficial plant-microbe interactions and to reduce pathogen infestation as well as to reveal novel bioactive substances of commercial interest.
Via Jean-Michel Ané, Kamoun Lab @ TSL
Chemical synthetic biology (CSB) is a branch of synthetic biology (SB) oriented towards the synthesis of chemical structures alternative to those present in nature. Whereas SB combines biology and engineering with the aim of synthesizing biological structures or life forms that do not exist in nature – often based on genome manipulation, CSB uses and assembles biological parts, synthetic or not, to create new and alternative structures. A short epistemological note will introduce the theoretical concepts related to these fields, whereas the text will be largely devoted to introduce and comment two main projects of CSB, carried out in our laboratory in the recent years. The “Never Born Biopolymers” (NBB) project deals with the construction and the screening of RNA and peptide sequences that are not present in nature, whereas the “Minimal Cell” project focuses on the construction of semi-synthetic compartments (usually liposomes) containing the minimal and sufficient number of components to perform the basic function of a biological cell. These two topics are extremely important for both the general understanding of biology in terms of function, organization and development, and for applied biotechnology.
New method of bacterial cell engineering can produce better, cheaper drug therapies
By Anne Ju "Therapeutic proteins, which provide cutting-edge treatments of cancer, diabetes and countless other diseases, are among today's most widely consumed biopharmaceuticals. By introducing bottom-up carbohydrate engineering into common bacterial cells, Cornell researchers have discovered a way to make these drugs cheaper and safer.
A research team led by Matthew DeLisa, associate professor of chemical and biomolecular engineering, has invented a novel method for engineering human therapeutic glycoproteins simply and quickly using E. coli bacteria as a platform. Their work is detailed online March 25 in Nature Chemical Biology...."
A major mitochondrial pathway that imbues cancer cells with the ability to survive in low-glucose environments has been pinpointed by researchers. By identifying cancer cells with defects in this pathway or with impaired glucose utilization, the scientists can predict which tumors will be sensitive to these anti-diabetic drugs known to inhibit this pathway.
What is clean eating, and where do I start?? 5 Week Challenge to turn you into a clean eater! THIS GOES ALONG WITH MY “BREAKING-UP WITH UNHEALTHY EATING HABITS” youtube video, check it out HERE. Week...
Chris Roberts-Antieau thinks art schools often destroy innate creativity and many student artists along with it. Being told she could not draw made her an instant art school dropout, but it did not change her mind about becoming an artist. “I knew I had artistic talent,” she recalls, “all I had to do was figure out how I could earn a living with it.” Now more than three decades later she is by every measure a great success.
“ Over the last week, science blogs described the sequencing instrument of Oxford Nanopore as everything from hi-tech washing machine to Nigerian scam, ZX-81 and Turbo Pascal combined together.”
Via Mel Melendrez-Vallard
“ Asia's lost continent, known as 'OK' , shaped ancient China, scientist claims South China Morning Post Yang's new model could explain some famous geological mysteries in East Asia, such as the Sanbagawa metamorphic belt in Japan.”
Via Catherine Russell
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