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H5N1: Fact, fiction, and pandemics - Writing for the Web

A reader tweeted me an interesting question yesterday: "If you wrote pandemic fiction (not zombie!) which virus would you use to disrupt society/high cfr?" Well, first of all I'd consider what other pandemic novelists had done, ...
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Influenza
Flu in all Forms, Be Informed...Not Panicked.
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Global circulation patterns of seasonal influenza viruses vary with antigenic drift : Nature : Nature Publishing Group

Global circulation patterns of seasonal influenza viruses vary with antigenic drift : Nature : Nature Publishing Group | Influenza | Scoop.it
Understanding the spatiotemporal patterns of emergence and circulation of new human seasonal influenza virus variants is a key scientific and public health challenge. The global circulation patterns of influenza A/H3N2 viruses are well characterized, but the patterns of A/H1N1 and B viruses have remained largely unexplored. Here we show that the global circulation patterns of A/H1N1 (up to 2009), B/Victoria, and B/Yamagata viruses differ substantially from those of A/H3N2 viruses, on the basis of analyses of 9,604 haemagglutinin sequences of human seasonal influenza viruses from 2000 to 2012. Whereas genetic variants of A/H3N2 viruses did not persist locally between epidemics and were reseeded from East and Southeast Asia, genetic variants of A/H1N1 and B viruses persisted across several seasons and exhibited complex global dynamics with East and Southeast Asia playing a limited role in disseminating new variants. The less frequent global movement of influenza A/H1N1 and B viruses coincided with slower rates of antigenic evolution, lower ages of infection, and smaller, less frequent epidemics compared to A/H3N2 viruses. Detailed epidemic models support differences in age of infection, combined with the less frequent travel of children, as probable drivers of the differences in the patterns of global circulation, suggesting a complex interaction between virus evolution, epidemiology, and human behaviour.
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MPCIRHC.ORG's curator insight, January 1, 2:59 PM

No vaccine works and the Pharma companies and their homeboys in nations governments - say get them anyway..they need the money.

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Model-Based Comprehensive Analysis of School Closure Policies for Mitigating Influenza Epidemics and Pandemics

Model-Based Comprehensive Analysis of School Closure Policies for Mitigating Influenza Epidemics and Pandemics | Influenza | Scoop.it

Author Summary School closure is a non-pharmaceutical intervention, considered for the mitigation of influenza epidemics and pandemics, whose impact and cost-effectiveness are still disputed.

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Prevalence, genetics, and transmissibility in ferrets of Eurasian avian-like H1N1 swine influenza viruses

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Avian Flu Diary: FluView Week 49 - A Rise In H1N1 & A Novel Virus In Minnesota

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Avian Flu Diary: CDC Clinician Guidance: Evaluating Patients Exposed to HPAI H5 Avian Flu

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A Message for National Influenza Vaccination Week — History of Vaccines

A Message for National Influenza Vaccination Week — History of Vaccines | Influenza | Scoop.it
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Evaluation of the Safety and Immunogenicity of a Candidate Pandemic Live Attenuated Influenza Vaccine (pLAIV) Against Influenza A(H7N9)

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Kuwait: One confirmed case of H1N1 in private school - FluTrackers

Kuwait: One confirmed case of H1N1 in private school - FluTrackers | Influenza | Scoop.it
KUWAIT, Nov 11 (KUNA) -- Minister of Education and Higher Education Bader Al-Essa said on Wednesday that there was one confirmed case of Swine Flu (H1N1) of a six
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Immunology and Cell Biology - Towards identification of immune and genetic correlates of severe influenza disease in Indigenous Australians

Immunology and Cell Biology - Towards identification of immune and genetic correlates of severe influenza disease in Indigenous Australians | Influenza | Scoop.it
Immunology and Cell Biology focuses on the general functioning of the immune system in its broadest sense, with a particular emphasis on its cell biology.
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Avian Flu Diary: The Lancet: Interventions To Reduce Zoonotic & Pandemic Risks From Avian Flu In Asia

Avian Flu Diary: The Lancet: Interventions To Reduce Zoonotic & Pandemic Risks From Avian Flu In Asia | Influenza | Scoop.it
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Host-Specific and Segment-Specific Evolutionary Dynamics of Avian and Human Influenza A Viruses: A Systematic Review

Understanding the evolutionary dynamics of influenza viruses is essential to control both avian and human influenza.

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Novel Reassortant Human-Like H3N2 and H3N1 Influenza A Viruses Detected in Pigs Are Virulent and Antigenically Distinct from Swine Viruses Endemic ... - PubMed - NCBI

J Virol. 2015 Nov 15;89(22):11213-22. doi: 10.1128/JVI.01675-15. Epub 2015 Aug 26.
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Avian Flu Diary: OIE Notification Of LPAI H5N3 In France: 4th New Strain In A Month

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Media Availability: Prime-Boost H7N9 Influenza Vaccine Concept Promising in Clinical Trial

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Human infection with avian influenza A(H7N9) virus – China

On 11 November 2015, the National Health and Family Planning Commission (NHFPC) of China notified WHO of 2 additional laboratory-confirmed cases of human infection with avian influenza A(H7N9) virus.
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How Vietnam Mastered Infectious Disease Control — NOVA Next | PBS

The country should be a hotbed of spillovers, but it hasn’t had a major outbreak in over a decade.
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Comparing Observed with Predicted Weekly Influenza-Like Illness Rates during the Winter Holiday Break, United States, 2004-2013

Comparing Observed with Predicted Weekly Influenza-Like Illness Rates during the Winter Holiday Break, United States, 2004-2013 | Influenza | Scoop.it

In the United States, influenza season typically begins in October or November, peaks in February, and tapers off in April.

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Emergence of Hemagglutinin Mutations During the Course of Influenza Infection

Emergence of Hemagglutinin Mutations During the Course of Influenza Infection | Influenza | Scoop.it

Influenza remains a significant cause of disease mortality. The ongoing threat of influenza infection is partly attributable to the emergence of new mutations in the influenza genome.

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