Influenza
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Generation of Replication-Proficient Influenza Virus NS1 Point Mutants with Interferon-Hyperinducer Phenotype

Generation of Replication-Proficient Influenza Virus NS1 Point Mutants with Interferon-Hyperinducer Phenotype | Influenza | Scoop.it
PLOS ONE: an inclusive, peer-reviewed, open-access resource from the PUBLIC LIBRARY OF SCIENCE. Reports of well-performed scientific studies from all disciplines freely available to the whole world.

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Influenza
Flu in all Forms, Be Informed...Not Panicked.
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Global circulation patterns of seasonal influenza viruses vary with antigenic drift : Nature : Nature Publishing Group

Global circulation patterns of seasonal influenza viruses vary with antigenic drift : Nature : Nature Publishing Group | Influenza | Scoop.it
Understanding the spatiotemporal patterns of emergence and circulation of new human seasonal influenza virus variants is a key scientific and public health challenge. The global circulation patterns of influenza A/H3N2 viruses are well characterized, but the patterns of A/H1N1 and B viruses have remained largely unexplored. Here we show that the global circulation patterns of A/H1N1 (up to 2009), B/Victoria, and B/Yamagata viruses differ substantially from those of A/H3N2 viruses, on the basis of analyses of 9,604 haemagglutinin sequences of human seasonal influenza viruses from 2000 to 2012. Whereas genetic variants of A/H3N2 viruses did not persist locally between epidemics and were reseeded from East and Southeast Asia, genetic variants of A/H1N1 and B viruses persisted across several seasons and exhibited complex global dynamics with East and Southeast Asia playing a limited role in disseminating new variants. The less frequent global movement of influenza A/H1N1 and B viruses coincided with slower rates of antigenic evolution, lower ages of infection, and smaller, less frequent epidemics compared to A/H3N2 viruses. Detailed epidemic models support differences in age of infection, combined with the less frequent travel of children, as probable drivers of the differences in the patterns of global circulation, suggesting a complex interaction between virus evolution, epidemiology, and human behaviour.
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MPCIRHC.ORG's curator insight, January 1, 2:59 PM

No vaccine works and the Pharma companies and their homeboys in nations governments - say get them anyway..they need the money.

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Avian Flu Diary: Emerg. Microbes & Inf.: Prevalence Of Influenza A in North Atlantic Gray Seals

Avian Flu Diary: Emerg. Microbes & Inf.: Prevalence Of Influenza A in North Atlantic Gray Seals | Influenza | Scoop.it
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Avian Flu Diary: Genetic Characterization of Avian Influenza Viruses In Vietnamese LBMs

Avian Flu Diary: Genetic Characterization of Avian Influenza Viruses In Vietnamese LBMs | Influenza | Scoop.it
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Avian Flu Diary: Sci Rpts: Characterization of Avian H7N2 in Wild Birds and Pikas in Qinghai-Tibet Plateau Area

Avian Flu Diary: Sci Rpts: Characterization of Avian H7N2 in Wild Birds and Pikas in Qinghai-Tibet Plateau Area | Influenza | Scoop.it
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Avian Flu Diary: Eurosurveillance: Emergence of A(H1N1)pdm09 Genogroup 6B In India, 2015

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Serial passaging causes extensive positive selection in seasonal influenza A hemagglutinin

bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
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Avian Flu Diary: CDC Guidance For People Exposed To Birds Carrying Avian Flu Viruses

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Avian Flu Diary: EID Journal: HPAI H5N8 Reintroduced Into South Korea By Migratory Waterfowl

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Model-Based Comprehensive Analysis of School Closure Policies for Mitigating Influenza Epidemics and Pandemics

Model-Based Comprehensive Analysis of School Closure Policies for Mitigating Influenza Epidemics and Pandemics | Influenza | Scoop.it

Author Summary School closure is a non-pharmaceutical intervention, considered for the mitigation of influenza epidemics and pandemics, whose impact and cost-effectiveness are still disputed.

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Prevalence, genetics, and transmissibility in ferrets of Eurasian avian-like H1N1 swine influenza viruses

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Avian Flu Diary: FluView Week 49 - A Rise In H1N1 & A Novel Virus In Minnesota

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Avian Flu Diary: J. Virology: Introduction, Reassortment and Persistence of Diverse Influenza A Viruses in Antarctica

Avian Flu Diary: J. Virology: Introduction, Reassortment and Persistence of Diverse Influenza A Viruses in Antarctica | Influenza | Scoop.it
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Avian Flu Diary: J. Virol: A Single Mutation Enhances H9N2 Binding To Human-Like Sialic Acid Receptors

Avian Flu Diary: J. Virol: A Single Mutation Enhances H9N2 Binding To Human-Like Sialic Acid Receptors | Influenza | Scoop.it
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Avian Flu Diary: PNAS: The Enigma Of Disappearing HPAI H5 In North American Migratory Waterfowl

Avian Flu Diary: PNAS: The Enigma Of Disappearing HPAI H5 In North American Migratory Waterfowl | Influenza | Scoop.it
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Avian Flu Diary: NEJM: Prolonged Shedding of Zika Virus Associated with Congenital Infection

Avian Flu Diary: NEJM: Prolonged Shedding of Zika Virus Associated with Congenital Infection | Influenza | Scoop.it
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Avian Flu Diary: JID: Benefits Of Early Use of Influenza Antivirals In Pregnancy

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Avian Flu Diary: WHO: Influenza at the Human-Animal Interface - January 2016

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Host-Specific and Segment-Specific Evolutionary Dynamics of Avian and Human Influenza A Viruses: A Systematic Review

Understanding the evolutionary dynamics of influenza viruses is essential to control both avian and human influenza.

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Novel Reassortant Human-Like H3N2 and H3N1 Influenza A Viruses Detected in Pigs Are Virulent and Antigenically Distinct from Swine Viruses Endemic ... - PubMed - NCBI

J Virol. 2015 Nov 15;89(22):11213-22. doi: 10.1128/JVI.01675-15. Epub 2015 Aug 26.
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