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VDU's blog: Influenza A(H7N9) virus case accumulation for 2013...

VDU's blog: Influenza A(H7N9) virus case accumulation for 2013... | Influenza | Scoop.it
RT @MackayIM: #H7N9 chart of cases worldwide, by week, with accumulation curve.
http://t.co/ACQcvr2IYs http://t.co/0EKVbtNgmY
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Influenza
Flu in all Forms, Be Informed...Not Panicked.
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Viral evolution: Past, present and future of influenza viruses : Nature Reviews Microbiology : Nature Publishing Group

Viral evolution: Past, present and future of influenza viruses : Nature Reviews Microbiology : Nature Publishing Group | Influenza | Scoop.it
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Can Monitoring Wikipedia Hits Show How Many People Have the Flu? - International Business Times UK

Can Monitoring Wikipedia Hits Show How Many People Have the Flu? - International Business Times UK | Influenza | Scoop.it
Can Monitoring Wikipedia Hits Show How Many People Have the Flu?
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Identifying the genetic basis of antigenic change in influenza A(H1N1)

Identifying the genetic basis of antigenic change in influenza A(H1N1) | Influenza | Scoop.it
Identifying the genetic basis of antigenic change in influenza A(H1N1) William T. Harvey, Victoria Gregory, Donald J. Benton, James P. J. Hall, Rodney S. Daniels, Trevor Bedford, Daniel T. Haydon, ...
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WHO provides update on avian influenza A (H7N9) in China

WHO provides update on avian influenza A (H7N9) in China | Influenza | Scoop.it
TweetThe World Health Organization said on Monday that four additional human cases of avian influenza (H7N9) were reported by the National Health and Family Planning Commission of China. Two cases were reported in Guangzhou City, Guangdong Province.
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Proteomic analysis at the subcellular level for host targets against influenza A virus (H1N1). - Antiviral Res. 2013

Influenza viruses (IVs) trigger a series of intracellular signaling events and induce complex cellular responses from the infected host cell. Accumulating evidence suggests that host cell proteins play an essential role in viral propagation and represent novel antiviral therapeutic targets. Subcellular proteomic technology provides a method for understanding regional differences at the protein level. The present study, which utilized subcellular proteomic technology, aimed to identify host cell proteins involved in influenza virus (HIN1) infection. Two-dimensional gel electrophoresis (2-DE) combined with mass spectrum (MS) was performed on protein extracts from the nuclei, cytoplasm, and mitochondria of infected and control human lung epithelial cells (A549). In total, 112 differentially expressed protein molecules were identified; 80 protein spots were successfully validated using MS. The differential expression of ISG15, MIF, PDCD5, and UCHL1 was confirmed by western blot. Furthermore, antisense oligodeoxyribonucleotide (ODN) targeting ISG15, MIF, PDCD5, and UCHL1 significantly mitigated HIN1 propagation, cytopathic effects, vRNA by RT-qPCR, and rescued cell viability in A549 cells. Taken together, the differentially expressed proteins identified in this study might provide novel targets for anti-influenza drug development.


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Sea Otters Can Get the Human Flu

Sea Otters Can Get the Human Flu | Influenza | Scoop.it
Scientists have no idea how the otters contracted the H1N1 virus, however
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Japan: Detection Of H5 Avian Flu At Poultry Farm

Japan: Detection Of H5 Avian Flu At Poultry Farm | Influenza | Scoop.it
Credit Wikipedia   # 8467   It’s been three years since Japan has had to deal with an H5 avian flu outbreak in poultry or wild birds (see OIE reports 29/06/11 Final report 48089 & 25/06/11 Final report 48022), but that respite appears over as...
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WHO | Human infection with avian influenza A(H7N9) virus – update

On 8 April 2014, the National Health and Family Planning Commission (NHFPC) of China notified WHO of two additional laboratory-confirmed cases of human infection with avian influenza A(H7N9) virus.
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Avian Flu Diary: The CDC Responds To The Cochrane Tamiflu Study

Avian Flu Diary: The CDC Responds To The Cochrane Tamiflu Study | Influenza | Scoop.it
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Comparison of Characteristics between Patients with H7N9 Living in Rural and Urban Areas of Zhejiang Province, China: A Preliminary Report (PLoS One., abstract, edited)

[Source: PLoS ONE, full page: (LINK). Abstract, edited.]
PLoS One. 2014 Apr 7;9(4):e93775. doi: 10.1371/journal.pone.0093775. eCollection 2014.
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Avian Flu Diary: Revisiting Tamiflu Efficacy (Again)

Avian Flu Diary: Revisiting Tamiflu Efficacy (Again) | Influenza | Scoop.it
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Serologic Evidence of Influenza A(H1N1)pdm09 Virus in Northern Sea Otters (Emerg Infect Dis., edited)

Serologic Evidence of Influenza A(H1N1)pdm09 Virus in Northern Sea Otters (Emerg Infect Dis., edited) | Influenza | Scoop.it
[Source: US Centers for Disease Control and Prevention (CDC), Emerging Infectious Diseases Journal, full page: (LINK).
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Sequence Changes Associated with Respiratory Transmission of H7N1 Influenza Virus in Mammals - Journal of Virology


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Modelling the effects of media during an influenza epidemic

Background:
Mass media is used to inform individuals regarding diseases within a population.
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UT Researchers Find New Target for Influenza A Virus - The Horn

UT Researchers Find New Target for Influenza A Virus - The Horn | Influenza | Scoop.it
Vaccine News Daily
UT Researchers Find New Target for Influenza A Virus
The Horn
Researchers at the University of Texas at Austin have identified a new protein target on the Influenza A virus.
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Hyperimmune intravenous immunoglobulin containing high titers of pandemic H1N1 hemagglutinin and neuraminidase antibodies provides dose-dependent protection against lethal virus challenge in SCID mice

Background: Convalescent plasma and fractionated immunoglobulins have been suggested as prophylactic or therapeutic interventions during an influenza pandemic.FindingsIntravenous immunoglobulin (IVIG) preparations manufactured from human plasma...
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NIH Funds Influenza Research and Surveillance Network

RT @sanofipasteur: U.S. NIH funds #influenza research and surveillance network http://t.co/ZwjCzXRe9K
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Tamiflu: A poster child for transparency in clinical trials?

Tamiflu: A poster child for transparency in clinical trials? | Influenza | Scoop.it
Thursday 10 April saw the publication of the Cochrane systematic review on oseltamivir and zanamivir, or Tamiflu (Roche) and Relenza (GlaxoSmithKline) to give them their better-known trade names. In short, the review found that Tamiflu doesn’t work quite as well as we thought; a finding that is the culmination of a four-and-a-half year battle for access to the raw data from the clinical trials.
The authors – Jefferson, Heneghan and colleagues – uncovered what they characterized as ‘multisystem failure’, with poorly-defined endpoints and confusion as to the authorship and contribution of the clinical trials. They also found that all studies were conducted against placebo, rather than against current best practice. Overall, the reviewers felt that the published studies were ...Read more
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WHO | Human infection with avian influenza A(H7N9) virus – update

The Centre for Health Protection (CHP), Hong Kong, SAR, China and the National Health and Family Planning Commission (NHFPC) of China recently notified WHO of 2 additional laboratory-confirmed cases of human infection with avian influenza A(H7N9)...
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Reasons to be cheeful: Influenza treatment

Reasons to be cheeful: Influenza treatment | Influenza | Scoop.it
Maybe there is some reason to be more optimistic about treating influenza.
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Rescooped by Mel Melendrez-Vallard from Virology and Bioinformatics from Virology.ca
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Pandemic Influenza: The Perpetual Challenge

Pandemic Influenza: The Perpetual Challenge | Influenza | Scoop.it

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Multisystem failure: the story of anti-influenza drugs | BMJ

Multisystem failure: the story of anti-influenza drugs | BMJ | Influenza | Scoop.it
Emergence of problemsOfficials have not unambiguously documented their reasons for stockpiling oseltamivir and zanamivir, but the decision seems to be based on the assumptions that the drugs would reduce hospital admissions and serious...
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Influenza viral vectors expressing the Brucella OMP16 or L7/L12 proteins as vaccines against B. abortus infection

Background:
We generated novel, effective candidate vaccine against Brucella abortus based on recombinant influenza viruses expressing the Brucella ribosomal protein L7/L12 or outer membrane protein (Omp)-16 from the NS1 open reading frame.
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New evidence, same conclusion: Tamiflu only modestly useful for influenza « Science-Based Medicine

New evidence, same conclusion: Tamiflu only modestly useful for influenza « Science-Based Medicine | Influenza | Scoop.it
Does Tamiflu have any meaningful effects on the prevention or treatment of influenza? Considering the drug's been on the market for almost 15 years, and is...
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Xinhua News: Extensive H5N1 Outbreaks In North Korean Poultry

Xinhua News: Extensive H5N1 Outbreaks In North Korean Poultry | Influenza | Scoop.it
  # 8452   Although we occasionally get hints of outbreaks of bird flu, or FMD, in North Korea, very rarely do we details out of that closed and secretive nation.
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Effectiveness of influenza vaccine against life-threatening RT-PCR-confirmed influenza illness in US children, 2010-2012

The evidence keeps mounting in favor of #influenza #vaccination to prevent severe outcomes in children: http://t.co/ytQQePYszc
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