cellular and molecular medicine
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Carcinogenesis and inflammatory processes

Divine Ndi Achiri

Divine Ndi Achiri's insight:

What are the modulatory processes of Carcinogenesis by polyunsaturated fatty acids...?

What is the inflammatory process involved in chemical carcinogenesis?

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Cardio-protection...

Divine Ndi Achiri's insight:

Mitochondria play an important role in energy production, Calcium ions homeostasis, and cell death in the organism.

To my students, just some hints: VDAC1, ROS, stress Kinase,   ,Ca2+ overload, Intrinsic pathway of Apoptosis, Mitochondrial permeability leads to the release of protease and nuclease activators,and hence to bioenergy failure.See also  stress genes expression

Post Ischaemic Cardioprotection;

-Inhibitors of Transitional Permeability Complex(ligands of cyclophilin D).

-Ca2+ activated K+ channels, or openers of mitochondrial ATP-sensitive.

-Modulation of the expression or activity of mitochondrial uncoupling proteins.

B-Cl2 protein engineering.

 

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