1936 - The Brotherhood takes a pro-Arab position and supports the Palestinian fighting against Zionist settlements. Muslim Brotherhood transforms itself into a political entity.
1940 - The Brotherhood creates the military wing "Secret Apparatus".
1948 - The Brotherhood begins terrorist and underground activities during the Arab-Israeli war. The Egyptian government arrests 32 leaders and bans the Brotherhood.
Feb 12, 1949 - Hassan-al Banna is killed in Cairo by Egyptian secret service agents.
1951 - Hassan Isma'il al-Hudaybi, a former judge, succeeds as the 2nd General Guide of the Brotherhood.
July 23, 1952 - The Egyptian Monarchy is overthrown in a military coup led by Muhammad Naguib and Gamal Abdel Nasser. The Brotherhood welcomes the coup, which it sees as subservient to British Imperialism.
1954 - After a failed assassination attempt by Abdul Munim Abdul Rauf on president Nasser, the Brotherhood is blamed and abolished. Thousands are sent to prisons and concentration camps. Others go into exile and underground throughout the Middle East.
1959 - Sayyid Qutb, an author and Islamic theorist, becomes a leading member of the Brotherhood. His literary works become very influential and they would later become the theoretical basis for many radical Islamic groups.
1964 - Nasser releases the imprisoned members.
August 29, 1966 - Qutb and two other members are executed by hanging. In 1965, they were accused of being apart of a plot to overthrow the state and assassinate Nasser.
1967-70 - The Brotherhood enters a period of quiet.
September 28, 1970 - Nasser suffers fatal heart attack.
1972 - Umar al-Tilmisani becomes the 3rd General Guide of the Brotherhood.
November 11, 1973 - Hassan Isma'il al-Hudaybi dies.
1970-79 - Nasser's successor, Anwar Sadat, became president of Egypt on October 15, 1970 and gradually releases imprisoned Brothers and enlists their help against leftist groups. The Brotherhood is more tolerated under Sadat, but still technically illegal.
1979 - The Brotherhood strongly opposes the peace agreement between Egypt and Israel.
October 6, 1981 - Sadat is assassinated by the violent Islamist group Tanzim al-Jihad. The Brotherhood is accused of supporting the assassination.
October 14, 1981 - Hosni Mubarak becomes president. He releases more Brotherhood members and offers an "olive branch" to the more moderate members.
1984 - Mubarak, recognises the Brotherhood as a religious organisation, but refuses its registration as a political party. So the Brotherhood fields candidates on independent tickets, winning 8 seats. For the next 8 years, The Brotherhood gains more political influence and establishes professional associations helping young graduates and the economically disadvantaged.
1986 - Umar al-Tilmisani dies. Muhammad Hamid Abu al-Nasr becomes the 4th General Guide of the Brotherhood.
1987 - The Egyptian Labour Party aligns itself with the Brotherhood.
1992 - Mubarak sets up repressive measures to curb this growing influence. Between 1993-96 thousands of members were arrested and sent to hard labour prison camps.
1996 - After Nasr's death, Mustafa Mashhur becomes the 5th General Guide of the Brotherhood. Mashur is considered a hard-liner and an active member of the "Secret Apparatus." Several middle-generation leaders leave the Brotherhood and form the new politcal party, Wasat.
2000 - The Brotherhood has 76 parliamentary candidates running as independents (including one woman). They win 17 of the 454 seats.
2002 - Ma'mun al-Hudaybi becomes the 6th General Guide of the Brotherhood.
2004 - Mohammed Mahdi Akef becomes the 7th General Guide of the Brotherhood.
2005 - Brotherhood members became the largest opposition bloc in the Egyptian parliament after winning 88 of the 454 seats in the 2005 legislative elections by running as independents. Shocked by the election results, Mubarak cracks down and detains hundreds of members.
2010-present - Mohammed Badie becomes the 8th General Guide of the Brotherhood.
2010 - The Brotherhood fail to win any seats in elections and declare election fraud.
February 2011 - Mubarak steps down and hands power to the military. The Brotherhood begins its new political wing, the Freedom and Justice Party. Mohamed Morsi leads the party.
May 2012 - The Brotherhood's Mohamed Morsi wins 52% of the presidential vote. He is the first democratically elected president in Egypt.
July 3, 2013 - The military removes President Morsi following week-long mass demonstrations calling on him to quit. He's replaced by Adly Mansour, the head of Supreme Constitutional Court.
August 2013 - Military and security forces launch raids destroying two large pro-Morsi protest camps. Hundreds are killed and thousands are wounded.