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Rescooped by carlos leal from Amazing Science!

Novel Genetic Patterns May Make Us Rethink Biology and Individuality - The Almagest

Novel Genetic Patterns May Make Us Rethink Biology and Individuality - The Almagest | Education and Technology |

Professor of Genetics Scott Williams, PhD, of the Institute for Quantitative Biomedical Sciences (iQBS) at Dartmouth’s Geisel School of Medicine, has made two novel discoveries: first, a person can have several DNA mutations in parts of their body, with their original DNA in the rest—resulting in several different genotypes in one individual—and second, some of the same genetic mutations occur in unrelated people. We think of each person’s DNA as unique, so if an individual can have more than one genotype, this may alter our very concept of what it means to be a human, and impact how we think about using forensic or criminal DNA analysis, paternity testing, prenatal testing, or genetic screening for breast cancer risk, for example. Williams’ surprising results indicate that genetic mutations do not always happen purely at random, as scientists have previously thought. His work, done in collaboration with Professor of Genetics Jason Moore, PhD, and colleagues at Vanderbilt University, was published in PLOS Genetics journal.[1]

Genetic mutations can occur in the cells that are passed on from parent to child and may cause birth defects. Other genetic mutations occur after an egg is fertilized, throughout childhood or adult life, after people are exposed to sunlight, radiation, carcinogenic chemicals, viruses, or other items that can damage DNA. These later or “somatic” mutations do not affect sperm or egg cells, so they are not inherited from parents or passed down to children. Somatic mutations can cause cancer or other diseases, but do not always do so. However, if the mutated cell continues to divide, the person can develop tissue, or a part thereof, with a different DNA sequence from the rest of his or her body.


“We are in reality diverse beings in that a single person is genetically not a single entity—to be philosophical in ways I do not yet understand—what does it mean to be a person if we are variable within?” says Williams, the study’s senior author, and founding Director of the Center for Integrative Biomedical Sciences in iQBS. “What makes you a person? Is it your memory? Your genes?” He continues, “We have always thought, ‘your genome is your genome.’ The data suggest that it is not completely true.”


In the past, it was always thought that each person contains only one DNA sequence (genetic constitution). Only recently, with the computational power of advanced genetic analysis tools that examine all the genes in one individual, have scientists been able to systematically look for this somatic variation. “This study is an example of the type of biomedical research project that is made possible by bringing together interdisciplinary teams of scientists with expertise in the biological, computational and statistical sciences.” says Jason Moore, Director of the iQBS, who is also Associate Director for Bioinformatics at the Cancer Center, Third Century Professor, and Professor of Community and Family Medicine at Geisel.


Having multiple genotypes from mutations within one’s own body is somewhat analogous to chimerism, a condition in which one person has cells inside his or her body that originated from another person (i.e., following an organ or blood donation; or sometimes a mother and child—or twins—exchange DNA during pregnancy. Also, occasionally a person finds out that, prior to birth, he or she had a twin who did not survive, whose genetic material is still contained within their own body).[2] Chimerism has resulted in some famous DNA cases: one in which a mother had genetic testing that “proved” that she was unrelated to two of her three biological sons.[3]

As suggested by Maria Schnee (

1 Williams, Scott, et al., Recurrent tissue-specific mtDNA mutations are common in humans.

2 Strain L, Dean JC, Hamilton MP, Bonthron D. A true hermaphrodite chimera resulting from embryo amalgamation after in vitro fertilization. N Engl J Med 1998;(338):166-9/

3 Norton AT and Zehner O. Project MUSE: Today’s Research, Tomorrow’s Inspiration.

Via Dr. Stefan Gruenwald
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Rescooped by carlos leal from The 21st Century!

How To Get Started With A BYOD Classroom - Edudemic

How To Get Started With A BYOD Classroom - Edudemic | Education and Technology |
Implementing a BYOD classroom can (and should) take quite a bit of time. That is, of course, if you want it to succeed. Here are some tips to know.

Via Dr. Susan Bainbridge
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Rescooped by carlos leal from 21st Century Learning and Teaching!

Visual Thinking and Seeing Creatively [Infographic]

Visual Thinking and Seeing Creatively [Infographic] | Education and Technology |

Via Gust MEES
Deborah Chad's curator insight, August 31, 2013 6:02 PM

More inforgraphics and thinking again this is the way to present the FH journey from PD through implementation

Bonnie Bracey Sutton's curator insight, September 3, 2013 12:42 PM

Good info!

Siri Anderson's curator insight, September 4, 2013 10:25 AM

Regardless of discipline this process can help organize student consideration of what is and what can be!

Rescooped by carlos leal from Tools for Teachers & Learners!

Roon — The easiest way to blog

Roon — The easiest way to blog | Education and Technology |

Via Nik Peachey
Walter Rubén Tur's comment, August 3, 2013 9:55 PM
hay algún vídeo de cómo utilizarla, en castellano, gracias
Nik Peachey's comment, August 4, 2013 3:11 AM
There's quite a long review and brief tutorial of Roon here: I particularly like the comment in the summary "Sometimes we get caught up in complex blogging platforms, plugins and more. Roon takes all of that away and ensures that you focus on what matters the most – your words." A rich feature set isn't always an advantage. Roon certainly isn't a competitor to WordPress, but it does make it easy to just get down to writing. For students that can be quite an advantage.
Tracee Orman's curator insight, August 4, 2013 9:14 AM

I just tried Roon out and made a post (on my Mac, by the way). I wanted to try it to see if it was something to share with students. It was pretty easy, though figuring out how to change the title of the post from "Untitled" was frustrating (I assumed the "Header" was the title...not so. You just click on it after you save and can change it in the sidebar.). 


I'm not sure what the point of giving your blog a title was when it posts as your user name and never shows your blog title. My advice: use your blog title as your user name. 


Not sure if I will use this with my students, but it is a simple and easy format. And free. Here's my simplistic post:

Rescooped by carlos leal from Tools for Teachers & Learners!

Free online video editor. Make a video using Shotclip.

Free online video editor. Make a video using Shotclip. | Education and Technology |
Easy and free online video editor. Edit videos and photos to make great home movies.

Via Nik Peachey
BookChook's curator insight, October 15, 2013 9:01 PM
Free version = 15 mins per month.
KB...Konnected's curator insight, February 11, 2014 9:24 AM

Free version provides up to 15 minutes of video export each month.

Meryl van der Merwe's curator insight, February 12, 2014 8:22 AM

Videos are a great way to "test" knowledge - so this tool is a useful one for teachers

Rescooped by carlos leal from iPads, MakerEd and More in Education!

A Powerful App For Every Level Of Bloom's Taxonomy - Edudemic

A Powerful App For Every Level Of Bloom's Taxonomy - Edudemic | Education and Technology |

"There are a ton of apps out there that address different ideas in the Bloom’s Taxonomy hierarchy. There are a multitude of resources out there that list tons of apps that are relevant. Some may be useful to you, some not, but either way, that’s a lot of information to sort through. So we pulled together a list of six apps – one for each level of understanding in the Bloom’s scheme. There are obviously innumerable combinations that you can shuffle together to make a grouping that works great for you – this is just one (six!) option(s)."

Via John Evans
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Rescooped by carlos leal from 21st Century Learning and Teaching!

50 Awesome Facts About Earth To Share With Your Class [Infographic]

50 Awesome Facts About Earth To Share With Your Class [Infographic] | Education and Technology |
I bet you don't know the vast majority of these facts about Earth. I sure didn't and thought I was on my game. Guess not!

Via Gust MEES
Diana Turner's curator insight, August 18, 2013 4:57 PM

Geography factoids to stimulate academic reading and conversation in an intermediate ESL class.

Jacqui Sharp's curator insight, August 18, 2013 5:13 PM

I like how the information in this infographic is broken up into parts Space, Atmosphere, Sea, underearth and ground. It has lots of statistics that are backed up by sources.

Ness Crouch's curator insight, August 19, 2013 4:13 PM

Love this! I will share this one with my class

Rescooped by carlos leal from Story and Narrative!

Let Me Tell You “About Me” - Seven Story Learning

Let Me Tell You “About Me” - Seven Story Learning | Education and Technology |

"Why the story on your about me page matters and how to improve it. Guest post by Daniel McInerny, The Comic Muse.


My passion is to help businesses and organizations tell their stories. I am an author of fiction for both children and adults. I spend my days immersed in storytelling.


So why does my “About Me” page stink on ice?


It’s not an official page. My “About Me” page is found via the “Hello!” tab on my navigation bar. Although I’m currently working on a much more effective “About Me” presentation, I’m going to leave this one up for awhile so that you can make a meticulous study of its multitudinous awfulness.


What’s so awful about it?"

Via Gregg Morris
Gordon Diver's comment, August 7, 2013 3:19 PM
Great share Karen - Some excellent suggestions that I'll be sure to incorporate
Karen Dietz's comment, August 7, 2013 8:15 PM
Hans, even I get help for my About page -- and it is still a work in progress!
Karen Dietz's comment, August 7, 2013 8:16 PM
Yes, Kati -- that is a unique twist to include in your About page. And Gordon, glad you like the suggestions. Time to revisit my own and update it!
Rescooped by carlos leal from Tools for Teachers & Learners!


DebateGraph | Education and Technology |
Debate map visualization of: 12,000+ maps and counting! Click on the bubbles to learn more – and log-in to create free public and private maps on any topic.

Via Nik Peachey
Camelia Mojica Rodríguez's comment, August 11, 2013 9:44 AM
Buen día Gilberto, recibe un saludo desde Tabasco y te comento que cada día es un paso en firme que damos para lograr lo que gentilmente ustedes nos compartieron en México. Muchas gracias.
Dico Krommenhoek's curator insight, August 12, 2013 5:31 AM

Dit ziet er goed uit. In verschillende views kan de mindmap worsten gebruikt om sterkte van ingebrachte ideeën weer te geven, of context te bieden. om enkele mogelijkheden te bekijken

Martha Schade's curator insight, August 13, 2013 6:31 AM

What a great way to develop your own maps. Have a look at the video to get an idea of the possibilities!