Ebola News and Views
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Surge in Guinea, activity in Sierra Leone stall Ebola decline

Surge in Guinea, activity in Sierra Leone stall Ebola decline | Ebola News and Views | Scoop.it
Although response efforts have curbed exponential growth, getting to zero will be a 'long and bumpy road.'
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Implementation of the International
Health Regulations (2005)
Report of the Review Committee on the Role of the
International Health Regulations (2005) in the
Ebola Outbreak and Respons

A69/21
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Options for strengthening information-sharing on
diagnostic, preventive and therapeutic products and
for enhancing WHO’s capacity to facilitate access to
these products, including the establishment...

A69/29
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A timeline for conducting your clinical trial 

A timeline for conducting your clinical trial  | Ebola News and Views | Scoop.it
This year, in celebration of International Clinical Trials Day on 20 May, BioMed Central has put together a timeline of the stages of conducting a clinical trial. We’ll reveal more stages throughout the week, in the lead up to the day itself. We’ve invited some of the greats in the field to comment on why the stage is important to a trial, what should be considered and why it should be considered at that point in the trial timeline.
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Facing forward after Ebola: questions for the next director general of the World Health Organization

Facing forward after Ebola: questions for the next director general of the World Health Organization | Ebola News and Views | Scoop.it
When the member states of the World Health Organization (WHO) elect a new director general in May 2017, they will decide the future of the organisation. The agency needs a strong global health leader determined to regain the trust of the international community and to position WHO in a rapidly changing environment.1 The history of director general elections indicates that member states consider many factors when choosing a candidate: political alliances, diplomatic deals, and regional considerations all come into play. This makes it hard to decide on the best candidate for the job.
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How black bin bags and common sense helped end an epidemic, and what we can learn from it

How black bin bags and common sense helped end an epidemic, and what we can learn from it | Ebola News and Views | Scoop.it
Rather than formal health systems, it was local common sense, allied to local ingenuity, that was crucial in ending Ebola. Is it time for a bottom-up citizen science?
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Preparedness of institutions around the world for managing patients with Ebola virus disease: an infection control readiness checklist

Preparedness of institutions around the world for managing patients with Ebola virus disease: an infection control readiness checklist | Ebola News and Views | Scoop.it
The results from our survey reveal that the general preparedness levels for management of potentially suspected cases of Ebola virus disease is only partially adequate in hospitals. Hospitals designated for admitting EVD suspected and proven patients had more frequently implemented Infection Control preparedness activities than hospitals that would subsequently transfer potential EVD cases to other centres. Results from this first international survey provide a framework for future efforts to improve hospital preparedness worldwide.
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Ebola vaccine development plan: ethics, concerns and proposed measures

Ebola vaccine development plan: ethics, concerns and proposed measures | Ebola News and Views | Scoop.it
Successful Ebola vaccine development research requires concerted efforts at public dialogue to address misconceptions, equity and justice in participant selection, and honest discussions about risks, benefits and future access. Public dialogue about Ebola vaccine research plans is crucial and should be conducted by trusted locals and negotiated between communities, researchers and ethics committees in research study sites.
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The first mile: community experience of outbreak control during an Ebola outbreak in Luwero District, Uganda

The first mile: community experience of outbreak control during an Ebola outbreak in Luwero District, Uganda | Ebola News and Views | Scoop.it
Given the available anthropological knowledge of a previous outbreak in Northern Uganda, it is surprising that so little serious effort was made this time round to take local sensibilities and culture into account. The “first mile” problem is not only a question of using local resources for early detection, but also of making use of the contextual cultural knowledge that has already been collected and is readily available. Despite remarkable technological innovations, outbreak control remains contingent upon human interaction and openness to cultural difference.
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Viraemia and Ebola virus secretion in survivors of Ebola virus disease in Sierra Leone: a cross-sectional cohort study 

Viraemia and Ebola virus secretion in survivors of Ebola virus disease in Sierra Leone: a cross-sectional cohort study  | Ebola News and Views | Scoop.it
Patients recovering from Ebola virus disease who do not meet the case definition for acute disease pose a low infection risk to health-care providers 6 weeks after clearance of viraemia. Personal protective equipment after this time might be limited to standard barrier precautions, unless contact with fluids from sanctuary sites is envisaged.
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New Evidence of Long-lasting Persistence of Ebola Virus Genetic Material in Semen of Survivors

Ninety-eight semen specimens were obtained for Ebola virus (EBOV) RNA screening from 68 men in Guinea during the convalescent phase of EBOV infection. Ten samples from 8 men were positive for EBOV up to 9 months after onset of the disease, with decreasing trends in the proportion of positive samples and the level of viral RNA. Safe sex practices should be observed after discharge from treatment centers.
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Toward Sustainable and Effective Control: Experience of China Ebola Treatment Center in Liberia

Noteworthy, China ETC, independently run by the Chinese government in responding to the EVD epidemic crisis, has been formally transferred to local government as scheduled on May 13, symbolizing its decommission after stopping EVD epidemic. China ETC has admitted totally 177 suspected, probable, or confirmed EVD cases, among which 60% (6 out of 10) confirmed Ebola patients were cured within a 6-month mission. Additionally, the dedicated “zero infection” to 444 China ETC healthcare workers (359 Chinese medical staffs and 85 local employees) further revealed the success of China in fighting against several deadly contagious diseases such as Ebola disease and malaria. Besides that WHO recommended standard for personal protection equipment (PPE) wearing has been adopted, China ETC has provided some unique and invaluable experience in infection control and treatment center operation, which would accelerate the response to newly emerged infectious disease particularly in resource-constrained countries where medical supplies are nearly inadequate or exhausted.
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The International Health Regulations:
The Governing Framework for Global
Health Security

Policy Points: The International Health Regulations (IHR) are the governing framework for global health security yet require textual and operational reforms to remain effective, particularly as parallel initiatives are developed. The World Health Organization (WHO) is the agency charged with oversight of the IHR, and its leadership and efficient functioning are prerequisites for the effective implementation of the IHR. We reviewed the historical origins of the IHR and their performance over the past 10 years and analyzed all of the ongoing reform panel efforts to provide a series of politically feasible recommendations for fundamental reform. This article offers proposals for fundamental reform—with politically feasible pathways—of the IHR, their operations and implementation, WHO oversight, and State Party conformance. Co
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Deaths, late deaths, and role of infecting dose in Ebola virus disease in Sierra Leone: retrospective cohort study

Deaths, late deaths, and role of infecting dose in Ebola virus disease in Sierra Leone: retrospective cohort study | Ebola News and Views | Scoop.it

To assess the frequency of fatal recrudescence from Ebola virus disease after discharge from treatment centres, and explore the influence of infecting dose on case fatality rates.
Conclusions In this study of survivors in Western Area, Sierra Leone, late recrudescence of severe Ebola virus disease appears to be rare. There was no evidence for an effect of infecting dose (as measured by exposure level) on the severity of disease.

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As Ebola Wanes, Guinea, Liberia, Sierra Leone, and World Look to Curb Next Pandemic

As Ebola Wanes, Guinea, Liberia, Sierra Leone, and World Look to Curb Next Pandemic | Ebola News and Views | Scoop.it

As Ebola outbreak wanes, Guinea, Liberia and Sierra Leone show what could have been done to prevent Ebola’s spread—and what can be done now to stop the next pandemic.
The recent Ebola epidemic infected more than 28,000 people in Guinea, Liberia and Sierra Leone, costing them approximately $2.8 billion in GDP losses. Without a strong system in place, the world will continue to move from crisis to crisis, killing thousands and destabilizing economies. To respond to this, at the G7 Finance Ministers’ meeting this week, leaders will discuss the Pandemic Emergency Financing Facility, a fast-disbursing financial mechanism that could help stem an outbreak before it reaches pandemic proportions

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Late Ebola virus relapse causing meningoencephalitis: a case report 

Late Ebola virus relapse causing meningoencephalitis: a case report  | Ebola News and Views | Scoop.it
Our report shows that previously unanticipated, late, severe relapses of Ebola virus can occur, in this case in the CNS. This finding fundamentally redefines what is known about the natural history of Ebola virus infection. Vigilance should be maintained in the thousands of Ebola survivors for cases of relapsed infection. The potential for these cases to initiate new transmission chains is a serious public health concern.
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Infection prevention and patient safety improvement in developing countries thanks to sodium hypochlorite production devices

Infection prevention and patient safety improvement in developing countries thanks to sodium hypochlorite production devices | Ebola News and Views | Scoop.it
AT’s devices are now used in thirty countries. Laboratory empirical studies and data gathered on the field have shown that such devices are able to produce on a regular basis a SH equivalent to 6g/L of active chlorine. This concentration is in line with recommendations of CDC for the disinfection in health centers in the Ebola context (CDC, 2015) and with the recommendations of the WHO regarding infection control in health care facilities (WHO, 2004). HS is also recognized as an efficient disinfectant for drinkable water. Water quality is expected to have a huge influence on the prevalence of waterborne diseases. Chlorination is identified as the most cost-effective disinfection solution.
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Infection prevention and control of the Ebola outbreak in Liberia, 2014–2015: key challenges and successes

Infection prevention and control of the Ebola outbreak in Liberia, 2014–2015: key challenges and successes | Ebola News and Views | Scoop.it
Prior to the 2014–2015 Ebola outbreak, infection prevention and control (IPC) activities in Liberian healthcare facilities were basic. There was no national IPC guidance, nor dedicated staff at any level of government or healthcare facility (HCF) to ensure the implementation of best practices. Efforts to improve IPC early in the outbreak were ad hoc and messaging was inconsistent. In September 2014, at the height of the outbreak, the national IPC Task Force was established with a Ministry of Health (MoH) mandate to coordinate IPC response activities. A steering group of the Task Force, including representatives of the World Health Organization (WHO) and the United States Centers for Disease Control and Prevention (CDC), supported MoH leadership in implementing standardized messaging and IPC training for the health workforce. This structure, and the activities implemented under this structure, played a crucial role in the implementation of IPC practices and successful containment of the outbreak. Moving forward, a nationwide culture of IPC needs to be maintained through this governance structure in Liberia’s health system to prevent and respond to future outbreaks.
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Critiquing the response to the Ebola epidemic through a Primary Health Care Approach

Critiquing the response to the Ebola epidemic through a Primary Health Care Approach | Ebola News and Views | Scoop.it
The PHC approach offers an insightful critique of the global and regional factors which have compromised the response of health systems in Guinea, Liberia and Sierra Leone as well as suggesting what a strengthened EVD response might involve in the short, medium and long-term.
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Saving Money, Saving Lives: A Case Study on the Benefits of Digitizing Payments to Ebola Response Workers in Sierra Leone

At the height of the Ebola crisis, Sierra Leone turned to mobile wallets to make fast, accurate, and secure payments to Response Workers. Before digitization, cash payments were slow, inaccurate, and open to graft and theft.
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'I knew death was imminent': nurse Pauline Cafferkey on surviving Ebola 

'I knew death was imminent': nurse Pauline Cafferkey on surviving Ebola  | Ebola News and Views | Scoop.it

Via Ian M Mackay, PhD
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Post-Ebola recovery social investment fund (PERSIF) – Appraisal report

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Ebola virus disease surveillance and response preparedness in northern Ghana

Ebola virus disease surveillance and response preparedness in northern Ghana | Ebola News and Views | Scoop.it
n 2014 and 2015, a total of 10 suspected Ebola cases were clinically diagnosed from four districts. Out of the suspected cases, eight died and the cause of death was unexplained. All the 10 suspected cases were reported, none was confirmed. The informants had knowledge on EVD surveillance and data reporting. However, there were gaps such as delayed reporting, low quality protective equipment (e.g. gloves, aprons), inadequate staff, and lack of laboratory capacity. The majority (38/47) of the respondents were not satisfied with EVD surveillance system and response preparedness due to lack of infrared thermometers, ineffective screening, and lack of isolation centres.
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