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Harnessing the Power of the Digital Patient


Via Lionel Reichardt / le Pharmageek
Dominique Godefroy's insight:

The biopharmaceutical industry is currently facing a number of macro-environmental factors, which underscore its need to
think of itself not as a developer of singular products, but as a critical part of an interoperable system. This fundamental shift
must include a strategic approach for engaging with an increasingly informed and connected patient population.

The amount of medical information now available to patients online is truly remarkable. Coupled with a decrease in the amount
of time physicians can actually spend with their patients, today’s health care consumers are savvy, engaged and have a strong
desire to learn as much as they can about their diseases.

By not directly engaging with patients, biopharmaceutical companies are missing an enormous opportunity to reduce the time
and cost of clinical development and maximize the return on their development investments. However, by earning patient trust
and creating a two-way dialog, some companies have been able to engage patients to participate and remain in research; prove
product value and safety by directly gathering personal outcomes, medical records, and diagnostic data from labs or devices;
and accelerate product adoption and adherence.

This white paper discusses how biopharmaceutical companies can harness the power of the digital patient when it engages
them in the appropriate manner. Quintiles’ Digital Patient Unit was founded to continue to innovate around these areas
of opportunity.

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Des objets connectés contre Alzheimer ?

Des objets connectés contre Alzheimer ? | e-Santé Marketing Santé innovant | Scoop.it
On a vu de nombreux fabricants d’appareils électroniques s’intéresser de près ou de loin au secteur médical. A l’heure actuelle, l’initiative la plus notable est probablement le partenariat entre Novartis et Google pour des lentilles capables de mesurer la glycémie. Mais les personnes atteintes d’Alzheimer pourraient elles aussi bientôt voir des objets connectés spécifiques arriver…

En France, on estime à environ 900.000 le nombre de personnes atteintes de cette maladie dégénérative terrible qui entraîne le déclin progressif de la mémoire. Face à cela, il existe aujourd’hui très peu de solutions effectives, et il s’avère extrêmement difficile pour l’entourage de la personne atteinte d’Alzheimer de contrôler les déplacements et les activités de celle-ci. Depuis une année, on a vu plusieurs initiatives dans les objets connectés pour aider les personnes atteintes d’Alzheimer, nous avons décidé de vous les partager ici.

Si on est bien loin du grand nombre d’objets connectés déjà disponibles pour les diabétiques, on a vu quelques appareils assez intelligents qui pourraient vraiment accompagner les aidants dans leur travail au quotidien. Si le géant Toshiba et son nouveau bracelet connecté Silmee W20 et W21 (annoncés en début de mois au Japon) veulent véritablement se destiner à un usage médical, et particulièrement au suivi GPS des malades, la plupart des objets connectés pour Alzheimer ont été imaginés par des petits entrepreneurs ou organisations. Il ne serait pas surprenant de voir dans les années à venir un autre géant de la technologie s’y intéresser, en particulier quand on sait qu’environ 100 millions de personnes souffrent à travers le monde de troubles de la mémoire…
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Bayer HealthCare va soutenir cinq startups spécialisées dans la santé numérique

Bayer HealthCare va soutenir cinq startups spécialisées dans la santé numérique | e-Santé Marketing Santé innovant | Scoop.it

Bayer HealthCare a lancé le 21 août dernier son programme «Grants4Apps Accelerator» 2015 à Berlin. Grâce au soutien de l’entreprise, cinq startups du monde entier spécialisées dans la santé numérique vont développer leurs idées et stratégies commerciales pour apporter aux médecins, aux patients et aux consommateurs des logiciels, équipements et technologies innovants.

Cinq startups spécialisées dans la santé numérique se sont installées officiellement dans les locaux du «Grants4Apps Accelerator» situés au siège social de l’antenne pharmaceutique de l’entreprise, à Berlin. Chacune des startups bénéficie d’un soutien financier pouvant atteindre 50 000 euros. Elles seront présentes dans les locaux de Bayer jusqu’à fin novembre pour développer leurs projets numériques dans le secteur de la santé, notamment dans le domaine des analyses hormonales, de l’observance des patients, des schémas respiratoires, des essais cliniques et des carences en vitamines. Des dirigeants de Bayer et des experts externes accompagneront les startups dans le développement de leurs business models pendant cette période.

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3 Ways To Create Smarter, Connected Healthcare

3 Ways To Create Smarter, Connected Healthcare | e-Santé Marketing Santé innovant | Scoop.it

As the world becomes more connected, organizations will create and capture less and less value in traditional ways.


Emerging technologies have already made a significant impact, creating an economic environment that is far more connected and open, simple and intelligent, fast and scalable.


Consumers want more sophisticated and compelling experiences in all aspects of their lives. Organizations are under intense pressure to catch-up and deliver on a very different set of customer expectations.

These changes are coinciding with the emergence of new ecosystems. To capitalize on the demand — and not be left behind — in a rapidly transforming environment, organizations must act now to develop ecosystem strategies aligned to their particular environments. They must challenge and change their traditional organizational approach, make the right connections and drive forward to become the standout success story in this new age of ecosystems.

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Medical Insight Set to Flow from Semantic Data Lakes

Medical Insight Set to Flow from Semantic Data Lakes | e-Santé Marketing Santé innovant | Scoop.it
The potential for data analytics to disrupt healthcare delivery is large, and getting larger by the day. But in many cases, the need to hammer data into a structured format creates a barrier to productivity. Now a hospital chain in New York City is hoping to change that by adopting a Hadoop-based semantic data lake.

Located in the Bronx, Montefiore Health System is the first hospital to implement a semantic data lake as part of the New York City Clinical Data Research Network (NYC-CDRN), an association of seven hospitals in the NYC area that are sharing data. As the pioneer, Montefiore is working with several technology providers, including Intel and Franz, to test a big data system capable of delivering precision medicine.

Most Datanami readers are familiar with the term “data lake,” but a “semantic data lake” provides an interesting twist on the familiar concept. According to Franz CEO Jans Aasman, a semantic data lake employs a combination of technologies, including Hadoop, graph analytics, a semantic “triple store,” the SPARQL query language, and Spark-based machine learning, to allow doctors to connect the dots between patient conditions and a world of knowledge contained in structured internal systems, as well as unstructured data sources outside of the organization.
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Ipsos Healthcare | Digital Doctor Report 2015

Ipsos Healthcare | Digital Doctor Report 2015 | e-Santé Marketing Santé innovant | Scoop.it
Health systems across Europe are facing challenges with an ageing population, enduring chronic health conditions and limited budgets.

Digital health is often cited as the opportunity to help bridge the gap between optimum healthcare delivery and efficiency of service; however this cannot be achieved without healthcare professionals' input and support.

In order to keep abreast of these developments and help our clients better tailor their offerings, Ipsos Healthcare has sought to uncover how Doctors feel about digital health, and how they see its role developing in the future.
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Google Reveals Gigantic Ambitions To Fight Cancer, Diabetes, Parkinson's, Heart Problems

Google Reveals Gigantic Ambitions To Fight Cancer, Diabetes, Parkinson's, Heart Problems | e-Santé Marketing Santé innovant | Scoop.it

The newly announced business will be entirely focused on the billions of dollars of annual revenues on offer from helping patients with a range of major health issues, from diabetes, Parkinson’s, cancer and heart disease to the general quest to increase comfortable life span.The split is part of Google’s Alphabet reshuffle that has seen the clearer separation of activities such as advertising and self driving cars.At the head of the new health unit is Andy Conrad, who has an extensive nanotechnology and molecular biology background, and who was head of life sciences at the former Google X research division.Google co-founder Sergey Brin, never one to miss out on a big business opportunity, is determined for the company to position itself at the forefront of the immensely lucrative health tech market in several key areas.


Via Alex Butler
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Antonio Pastor Serrano's curator insight, August 26, 8:14 AM

añada su visión ...

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Roche buys Kapa to boost sequencing technology offering

Roche buys Kapa to boost sequencing technology offering | e-Santé Marketing Santé innovant | Scoop.it
Roche has added technology to tailor enzymes for specific applications in next-generation DNA and RNA sequencing through the acquisition of Kapa Biosystems.
Thermo

Next-generation sequencing (NGS) technologies are high-throughput technologies which allow the rapid sequencing of DNA and RNA in the study of genomics and molecular biology.

While Roche is already one of the major players in the sector (others include Illumina and Thermo Fisher through its acquisition of Life Technologies), the Swiss Pharma Giant has expanded its offering through the acquisition of Massachusetts-based genomics tools provider Kapa Biosystems.

“Kapa`s technology is not a NGS technology,” Roche spokesperson Claudia Schmitt told this publication. Rather, “Kapa provides a collection of essential components for NGS where the probe/library preparation is very enzyme intensive.”

This “custom enzyme evolution” technology, she continued, “allows for the generation of enormous libraries of enzyme variants, from which ideal forms of the enzyme can be rapidly selected for various applications in the NGS workflow,” advancing biomedical research by bypassing the constraints of native enzyme structure or function.
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Skin Cancer Checker App, SkinVision, Snags $3.4M To Move Beyond Moles

Skin Cancer Checker App, SkinVision, Snags $3.4M To Move Beyond Moles | e-Santé Marketing Santé innovant | Scoop.it
Can an app warn you that you might have skin cancer? Digital health startup SkinVision is using smartphone tech and vision algorithms to allow consumers to track changes to their moles. Users of its iOS and Android apps, which have been downloaded some 200,000 times since launch back in 2011, take a photo of a mole and the app then performs a visual analysis, with the aim of identifying suspicious growths such as melanoma.

“Skin cancer grows chaotically and potential suspicious moles are identified based on signs of non-natural growth,” explains CEO Dick Uyttewaal. “The algorithm within the online assessment reviews signs of non-natural growth of skin lesions and is based on an established mathematical methodology in biology called fractal geometry.

“The algorithm currently looks at seven different criteria and will be further improved based on the continuous growth in our database (currently in excess of 1 million pictures).”
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Les Appli pour les Neurologues sur MédecinGeek.

Les Appli pour les Neurologues sur MédecinGeek. | e-Santé Marketing Santé innovant | Scoop.it

MédecinGeek vous propose une sélection des différentes Applis pour Iphone et Androïd pour les Neurologues. Sclérose en Plaques, Neuroradiologie, Epilepsie, AVC et Migraine sont des Applis pour améliorer la prise en charge de vos patiens.


Via Medecin Geek, Philippe Marchal/Pharma Hub
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Gauss Surgical CEO sheds light on latest fundraise for app to calculate blood loss during surgery

Gauss Surgical CEO sheds light on latest fundraise for app to calculate blood loss during surgery | e-Santé Marketing Santé innovant | Scoop.it
As MedCity News reported yesterday, Gauss Surgical raised $3.4 million just a few months after it secured FDA 510(k) clearance for a digital health app that measures blood loss during surgery based on the amount of blood stored in cannisters.

In a phone interview with MedCity News, Gauss Surgical CEO Dr. Milton McColl confirmed that the latest funding is an extension of its Series A round and will be used to for sales and marketing support of the roll out of its latest app.

Promus Ventures led the round and its founding partner, Mike Collett, will serve as a board observer on Gauss Surgical’s board of directors. It’s an interesting move for an investment firm more known for its tech investments in companies like AngelList and Storify. Summation Health Ventures also participated in this round. Gauss has raised $12 million to date, McColl said.

One area in which the company sees a lot of potential for its app is obstetrics. Maternal hemmorhaging during childbirth is always a risk, but advances in data collection have revealed it’s an increasing cause of concern. The problem with the current practice of weighing sponges to estimate blood loss is that other fluids come into play, making the process time-consuming and inefficient.
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Voici comment Intel va aider à remporter la lutte contre le cancer

Voici comment Intel va aider à remporter la lutte contre le cancer | e-Santé Marketing Santé innovant | Scoop.it

Intel et l'Oregon Health & Science University (OHSU) ont mis au point une plate-forme 'cloud' spécifiquement destinée à la recherche en matière de cancer. Mais d'autres géants technologiques encore apportent leur aide dans le combat mené contre la maladie.


Au deuxième jour de l'Intel Developer Forum (IDF), Eric Dishman (47 ans), general manager de l'Intel Health Strategy & Solutions Group, a pris la parole. Cela faisait 23 ans qu'il luttait pour vaincre un cancer. Après avoir reçu l'aide d'experts dans le domaine et d'analystes de son génome, il a été complètement guéri en 'à peine' trois mois. Depuis lors, il est convaincu que le traitement personnalisé peut sauver des vies.


Dishman a fait l'objet d'une thérapie personnalisée sur base d'une analyse de son génome. Le gros problème, c'est que les données du génome occupent pas mal de giga et de téraoctets et sont réparties dans plusieurs centres de cancérologie, hôpitaux, universités et centres de recherche. La plate-forme 'Collaborative Cancer Cloud' qu'Intel a à présent mise en oeuvre conjointement avec l'Oregon Health & Science University devrait faciliter l'échange de ces données et leur analyse. Brian Druker, chercheur à l'Oregon Health & Science University, nous livre son avis: "Il a fallu patienter 23 ans, avant qu'Eric reçoive un traitement personnalisé. Nous devrions pouvoir y arriver en une seule journée et d'ici 2020, nous espérons vraiment que ce sera le cas."


Le 'nuage de cancérologie' reliera dans un premier temps l'université d'Oregon aux instituts académiques de Boston et d'Austin. Mais Druker a affirmé clairement aujourd'hui que des extensions seront rapidement réalisées. De son côté, Intel va dès l'an prochain mettre à la disposition d'autres acteurs certains éléments de la plate-forme 'cloud' en open source.

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Crowdfunding : le futur du financement de l'e-santé ?

Crowdfunding : le futur du financement de l'e-santé ? | e-Santé Marketing Santé innovant | Scoop.it
En parallèle des sources de financement et d’investissements « classiques » dans le secteur de l’e-santé et dans la sphère du Digital Health (voir à ce sujet l’article de Thomas Martinelli), on voit émerger de façon croissante depuis quelques années une forme alternative de financements, basés sur l’appel à contribution des particuliers via des plates-formes de gestion de dons : c’est le fameux principe du « crowdfunding ».
Le crowdfunding : une disruption dans le modèle de financement


En osant un parallèle, on pourrait dire que le crowdfunding est le pendant « financier » de ce qu’est le modèle Uber à la réalité terrain des projets, des solutions ou des services : en effet, il représente une disruption dans les modèles opérationnels et économiques, notamment parce qu’il contribue à faire émerger une économie collaborative et un modèle en « C to B » (en inverse du « B to C » classique), basé sur des offres et des services directement proposés par des particuliers à des particuliers, en profitant de la réactivité et de la disponibilité de ressources « locales » pour développer des business réactifs.

En terme de secteurs d’activité, ce type de financement, qui a démarré historiquement pour des projets dans le secteur culturel et musical (financement de production d’albums par des artistes indépendants ; œuvres d’arts, édition de livres…), est en train de s’étendre petit à petit à tous les secteurs d’activité et à tous les types de projets, du plus sérieux au plus loufoque (cf. le buzz récent sur le projet de crowdfunding mondial lancé pour rembourser la dette et financer le plan d’austérité de la Grèce !).

Naturellement, la santé n’est pas en reste, et il est intéressant de se demander quels impacts le crowdfunding peut avoir sur le financement et le développement des projets d’e-santé, ainsi que sur les modèles économiques concernés.


Le crowdfunding en santé : une réalité en 2015

Que ce soit sur des plateformes classiques ou dédiées de crowdfunding, les entreprises et start-ups du monde de la santé ont très vite su utiliser ce nouveau modèle de financement.

C’est le cas par exemple de Kolibree, qui propose la 1ère brosse à dents connectée qui promet de suivre l'efficacité des brossages quotidiens et de l'afficher sur smartphone. Elle a lancé un appel aux dons sur Kickstarter, la plate-forme américaine de crowdfunding, récoltant rapidement 70 000 dollars (51 000 euros). Mais c’est loin d’être la seule start-up à s’être financée par ce biais : Misfit pour son capteur d’activité physique Misfit Shine ou encore la start-up Kinsa pour la mise au point d’un thermomètre connecté n’ont pas hésité à recourir à ce système pour lancer leur activité et proposer leurs concepts sur le marché.

Des plateformes dédiées à la santé se multiplient par ailleurs, comme WellfundR pour financer des innovations en matière de santé ou MyPharmaCompany pour financer les programmes de recherche dans le domaine de la santé.

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Google Won the Internet. Now It Wants to Cure Diseases

Google Won the Internet. Now It Wants to Cure Diseases | e-Santé Marketing Santé innovant | Scoop.it
When Google co-founder Larry Page dropped his now-famous blog post revealing that Google was reorganizing itself as Alphabet, one of the most striking things was what he chose to highlight as the kind of work these newly independent non-Google companies would be pursuing.

“The companies that are pretty far afield of our main Internet products [are] contained in Alphabet instead,” Page wrote in the blog post announcing Alphabet’s existence. “Good examples are our health efforts: Life Sciences (that works on the glucose-sensing contact lens), and Calico (focused on longevity).”

Google has long dabbled in medicine, but Page’s announcement signaled that he wants biomedical research to be more than just a side project for his newly christened company. Behind the scenes, efforts were already well under way to transform Google into a place that was serious about life sciences.

Under Alphabet, life sciences will become its own independent division, though it doesn’t have an official name just yet. (The company says to expect more news soon.) But a few hints suggest the life sciences group had been operating fairly independently already. Last month, CFO Ruth Porat singled out life sciences during a quarterly earnings call as one of the areas Google sees as “longer-term sources of revenue.” To get there, the company has been quietly recruiting top scientific talent, from immunologists to neurologists to nanoparticle engineers.
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Nouveau site web pour mieux vivre avec un psoriasis

Nouveau site web pour mieux vivre avec un psoriasis | e-Santé Marketing Santé innovant | Scoop.it
Pour accompagner les patients souffrant de psoriasis, qui se sentent souvent isolés, le laboratoire AbbVie lance un nouveau site web : Points-psoriasis.fr. Présentation.

Depuis 2012, le laboratoire AbbVie, en collaboration avec l’association France Psoriasis, met à disposition des Points Conseil Psoriasis dans plus de 3 000 officines en France. Le rôle de ces espaces conseils est d’écouter et informer au quotidien, conseiller tout en rassurant, encourager à consulter un dermatologue ou inciter à contacter l’association de patients(pour un soutien, une mise à disposition de brochures, rencontrer d’autres malades…)

Pour accompagner ce programme, le laboratoire lance le site web Points-psoriasis.fr. L’objectif est d’informer sur la maladie et d’encourager les patients à consulter un dermatologue.
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Health System, Apps Must Evolve for Mobile Health Adoption To Take Off

Health System, Apps Must Evolve for Mobile Health Adoption To Take Off | e-Santé Marketing Santé innovant | Scoop.it
Technology tools continue to play an important role for patients, particularly those with chronic and life threatening illnesses. Seven in 10 people with a chronic condition went online to find information about it, according to research by the Pew Research Center. And, as the number of medical issues a person has increases, so too does their use of the Internet to gain information about their conditions.

In another survey, the Pew Research Center reports that nearly two-thirds of U.S. adults own a smartphone. Ownership is highest among younger adults, the affluent and educated individuals. Slightly more than six in 10 smartphone owners have used their phone to get information about a health condition in the past year, according to the survey.

As a society, our reliance on mobile technology and content-specific applications is clear. Yet, when it comes to gaining information about how to manage chronic illnesses, condition-focused websites and blogs remain the top technology tools patients turn to. That was the finding of a recent survey of nearly 14,000 members of the medical social networking site Inspire. Of those surveyed:

78% said condition-specific websites or blogs were the most helpful source of information used to better understand their health conditions; and
76% turned to online search engines.
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#OpenInno : Comment les startups aident le groupe pharmaceutique Roche à innover

#OpenInno : Comment les startups aident le groupe pharmaceutique Roche à innover | e-Santé Marketing Santé innovant | Scoop.it
Souvent dans le secret et donc peu enclins à parler de leurs recherches, les groupes pharmaceutiques commencent à s’ouvrir. Ils collaborent de plus en plus avec d’autres entreprises et notamment des startups. L’occasion de répondre avec plus de précision aux besoins des patients. Explications avec Isabelle Vitali, directrice de l’innovation et des partenariats du groupe Roche.

La diversité d’approches est source d’innovation, donc de progrès. Si une grande entreprise dispose de profils de grand talent, nul ne peut posséder toutes les expertises en interne. A l’heure du collaboratif, aucun acteur ne peut prétendre innover et créer de la valeur en travaillant seul. C’est également le cas dans le médical. Fort d’une culture très ancrée sur les partenariats de recherche, le groupe Roche a décidé de faire de l’innovation ouverte un pilier de sa stratégie. Il ne s’agit pas d’un programme mais bien une vision d’entreprise.

« Notre modèle de R&D est unique au sein du secteur biopharmaceutique. Nous avons trois entités de recherche distinctes : en Europe, la recherche Roche, aux USA, la recherche Genentech et au Japon, celle de Chugai », explique Isabelle Vitali, directrice de l’Innovation et des partenariats de Roche.
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E-santé : la prévention ne nécessite pas toujours d'initiatives onéreuses

E-santé : la prévention ne nécessite pas toujours d'initiatives onéreuses | e-Santé Marketing Santé innovant | Scoop.it
Un simple programme informatique en libre accès sur internet lancé par l’université de Southampton a permis de réduire le risque de contagion de maladies sur deux hivers... en rappelant les basiques de l’hygiène.

Pas besoin de déployer de grands moyens pour proposer une campagne qui incite les individus à la prévention en matière de maladie ? En tout cas, en ce qui concerne les maladies saisonnières et sous réserve d'un minimum de suivi. C'est ce qu'ont essayé de prouver des chercheurs de l'université de Southampton en Angleterre via leur dispositif PRIMIT. Celui proposait en effet à des participants, via des graphismes assez datés, les basiques que sont le nettoyage de main et les autres conseils pour ne pas attraper de rhumes. Résutat étonnant, le risque d'infection parmi les utilisateurs aura diminué de 14 % sur la période de test.
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How mobile apps can help young people with mental ill health

How mobile apps can help young people with mental ill health | e-Santé Marketing Santé innovant | Scoop.it
Jamie Prangnell shares his story of working with a mental health trust in developing a series of ‘game-style’ apps that aim to help improve young people’s chances of recovery.

Mental ill health is a huge issue for young people. It is estimated that one in five young people have a mental health problem in any given year.

Further research says that around half of all mental disorders begin before the age of 15, and 75% by 24. More than half of all adults with mental health problems saw such issues manifest in childhood, but were not formally diagnosed.

With ever-increasing pressures on young people around education, work and home life, there is a sad inevitability that the issue needs addressing.

Tools that enable prevention and early intervention are crucial on the road to recovery, especially for illnesses such as psychosis.

Clinicians are seeing technology as an essential part of the solution, particularly as access to formal services will be very difficult as demand is likely to outstrip supply.

Many companies are working with the NHS on app development. Appadoodle’s involvement has been with clinicians at Birmingham and Solihull Mental Health NHS Foundation Trust (BSMHFT), one of the largest such trusts in the country.

Early intervention in psychosis and other teams from BSMHFT wanted to look at new ways of engaging with young people, and apps were one such option.
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Health Train Express: Doctors' Virtual Consults With Patients To Double By 2020

Health Train Express: Doctors' Virtual Consults With Patients To Double By 2020 | e-Santé Marketing Santé innovant | Scoop.it
Thanks to expanding health insurance coverage, the number of virtual video consultations between primary health care providers and their patients will double in five years in the U.S., fueling the nation’s telehealth boom, according to a new analysis.

A new report from information and analytics firm IHS says video consultations will jump overall to nearly 27 million in the U.S. market, driven by the primary care market where insurance coverage is rapidly widening. IHS projects there will be cumulative annual growth of nearly 25% a year over the next five years to 5.4 million video consultations between primary care providers and their patients by 2020 from this year’s 2 million video consultations, IHS says. “We’ve seen growth in reimbursement,” Roeen Roashan, medical technology analyst with IHS said in an interview. “There’s no doubt payers are focused on virtual consultations. They are really pushing it.”
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MouthLab: Patients' vital signs are just a breath away

MouthLab: Patients' vital signs are just a breath away | e-Santé Marketing Santé innovant | Scoop.it
Engineers and physicians at the Johns Hopkins University School of Medicine have developed a hand-held, battery-powered device that quickly picks up vital signs from a patient's lips and fingertip. Updated versions of the prototype, called MouthLab, could replace the bulky, restrictive monitors now used to display patients' vital signs in hospitals and gather more data than is typically collected during a medical assessment in an ambulance, emergency room, doctor's office or patient's home.

In a study published in the September issue of the Annals of Biomedical Engineering, the MouthLab prototype's measurements of heart rate, blood pressure, temperature, breathing rate and blood oxygen from 52 volunteers compared well with vital signs measured by standard hospital monitors. The device also takes a basic electrocardiogram.

"We see it as a 'check-engine' light for humans," says the device's lead engineer, Gene Fridman, Ph.D., an assistant professor of biomedical engineering and of otolaryngology-head and neck surgery at Johns Hopkins. "It can be used by people without special training at home or in the field." He expects the device may be able to detect early signs of medical emergencies, such as heart attacks, or avoid unnecessary ambulance trips and emergency room visits when a patient's vital signs are good.
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Intractable pain may find relief in gold nanorods

Intractable pain may find relief in gold nanorods | e-Santé Marketing Santé innovant | Scoop.it
A team of scientists at Kyoto University’s Institute for Integrated Cell-Material Sciences (iCeMS) has developed a novel technique using gold nanorods to target pain receptors (“Thermosensitive Ion Channel Activation in Single Neuronal Cells by Using Surface-Engineered Plasmonic Nanoparticles”).Gold nanorods are tiny rods that are 1-100 nanometers wide and long. In comparison, a human hair is 100,000 nanometers wide. The team coated gold nanorods with a special type of protein that transports fat within the body known as a lipoprotein. This allowed the nanorods to bind efficiently to nerve cell membranes bearing a pain receptor called TRPV1 (transient receptor potential vanilloid type 1).

Near-infrared light was then applied to the nanorod-coated pain receptors. The nanorods heated up, activating the pain receptors to allow an influx of calcium ions through the membrane. Prolonged activation of TRPV1 is known to subsequently lead to their desensitization, bringing pain relief.Importantly, heating the gold nanorods enabled safe activation of the TRPV1 pain receptors alone, without affecting the membrane in which they lie.Previous studies had shown that magnetic nanoparticles (tiny particles in the nano-range made out of magnetic materials) are also able to activate TRPV1 receptors by applying a magnetic field.
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Wearable tech could diagnose lung problems by analyzing wheezes

Wearable tech could diagnose lung problems by analyzing wheezes | e-Santé Marketing Santé innovant | Scoop.it
If someone is wheezing, it usually means that they have a respiratory problem. Soon, however, a wheeze-analyzing wearable device may allow doctors to know what sort of respiratory problem a patient has – and how serious it is.

The system is being developed by Saba Emrani and Hamid Krim, researchers with the National Science Foundation Nanosystems Engineering Research Center for Advanced Self-Powered Systems of Integrated Sensors and Technologies (ASSIST) at North Carolina State University. It consists of two main components.

First, there are body heat-powered sensors that are worn continuously by the patient, as they go about their daily routine. The second part of the system is software that monitors those sensors. When it detects wheezing sounds through them, it uses a custom algorithm to assess those sounds’ onset time, pitch and volume.

By analyzing those parameters, it’s possible to determine the problem’s location within the lungs, along with its severity. Using that information, doctors can then make more informed decisions regarding treatment. According to Krim, the system is accurate regardless of the size of the patient.
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Google is doubling down on biotech

Google is doubling down on biotech | e-Santé Marketing Santé innovant | Scoop.it

The company is turning the team that develops smart contact lenses and other healthcare initiatives into a full-fledged, standalone company rather than a lab project.

The life sciences group will "graduate" from the Google X labs and become its own separate company under the new Alphabet corporate structure, Google co-founder Sergey Brin said on Thursday.

Andy Conrad, a molecular biologist who joined Google in 2013, will be the CEO of the new company, Brin said.

"While the reporting structure will be different, their goal remains the same. They’ll continue to work with other life sciences companies to move new technologies from early stage R&D to clinical testing—and, hopefully—transform the way we detect, prevent, and manage disease," Brin explained.

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Illumina CEO Jay Flatley Launches Helix to Stoke Consumer Use of Genomic Data

Illumina CEO Jay Flatley Launches Helix to Stoke Consumer Use of Genomic Data | e-Santé Marketing Santé innovant | Scoop.it
The CEO of the world’s leading DNA sequencing company says he knows how to finally get consumers interested in their genomes: by creating an enormous app store for genetic information.

Yesterday, Illumina said that along with Warburg Pincus and Sutter Hill Ventures it was investing $100 million in a new company called Helix to make consumer genomics part of the Internet mainstream.

Illumina’s CEO, Jay Flatley, said in an interview that Helix will subsidize the cost of decoding people’s genomes in hopes of spurring the creation of consumer apps that will draw on the DNA data repeatedly. “You saw what happened with the Apple app store: it just unleashed the consumer side because apps are so cheap to make,” says Flatley, who will be chairman of the new company.

Flatley says that when Helix goes live next year it will sequence and store consumers’ DNA, then sell them pay-as-you-go access to it through the apps, which will be offered by partners, the first of which are LabCorp and the Mayo Clinic. Profits will get shared, in a model similar to the one for Apple’s app store. If Helix succeeds, it will operate the largest sequencing laboratory of any kind, Flatley predicts.
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MediSafe partners with Human API to help users see connections between medication and their medical data

MediSafe partners with Human API to help users see connections between medication and their medical data | e-Santé Marketing Santé innovant | Scoop.it
The hope is that patients will be able to see in more concrete terms the connection between taking their medication and improvements, or declines, in their health. It’s the kind of information that could improve the quality of their interactions with doctors and other healthcare professionals.

In a phone interview with MediSafe CEO Omri Shor, he said: “We don’t see many hospitals offering actionable information on patient portals. Everyone is talking about that trend, but this is [a reflection] of the trend.”

The deal has been coming together for awhile, according to CEOs for both companies. Shor said he and Human API CEO Andrei Pop had been interested in integrating their platforms since MediSafe closed its Series A round. Although the collaboration is designed to provide an additional service for MediSafe’s 2 million users, Shor views it as especially useful for people on multiple medications and/or who have chronic conditions.

Pop said the deal was a step toward boosting patient empowerment by giving them greater access to their own data.He added that the deal also is closer to the next generation of healthcare tools that will be more consumer-centric. It puts patients in the position not only of gaining access to more of their healthcare data but also making it easier to share with whichever organizations they choose.
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