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Duchenne Research
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Pre-clinical efficacy data for WNT7A-analog program

Fate Therapeutics, Inc., a biopharmaceutical company engaged in the discovery and development of adult stem cell modulators, announced today the presentation of preclinical data from its WNT7a protein analog program for the treatment of muscular dystrophy at the MDA 2013 Scientific Conference, April 21-24, in Washington DC. The presentations describe the engineering of pharmaceutically optimized WNT7a protein analogs, as well as their mechanism of action and efficacy profile in preclinical pharmacology studies.

 

"We are working towards the nomination of an investigational new drug (IND) candidate later this year, and are excited about the potential to advance this new mechanism toward clinical studies." - Christian Weyer, President and CEO of Fate Therapeutics

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Pre-clinical results on naproxcinod in Duchenne

Pre-clinical results on naproxcinod were presented at the MDA Scientific Conference in a poster entitled “Long-term treatment with naproxcinod significantly improves skeletal and cardiac disease phenotype in mdx mouse model of dystrophy." The effects of naproxcinod were investigated on skeletal and cardiac muscle function in mdx mice. The results of the study suggest that naproxcinod may have potential as a safe therapeutic option.

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