Interferon-free regimens containing sofosbuvir (Sovaldi) plus simeprevir (Olysio) cured about three-quarters of genotype 1 chronic hepatitis C patients with advanced cirrhosis and MELD scores >10 in the real-world HCV-TARGET study, researchers reported at the European Association for the Study of the Liver (EASL) 50th International Liver Congress last month in Vienna.
The sustained response rate in HCV-TARGET fell to 39% for genotype 3, but another study found that 70% of genotype 3 patients
Sharing injecting equipment is associated with a low per-event probability of hepatitis C virus (HCV) transmission, Australian investigators report in the online journal PLOS ONE. Their analysis also showed that sharing injecting equipment with someone with hepatitis C had a transmission probability of up to 6%, depending on factors such as cleaning of equipment and HCV viral load. Because the per-event probability was so low, the investigators believe that HCV prevention campaigns should focus
The evidence from the 21 studies analysed shows that educational and training interventions for peers and family members, complemented by take-home naloxone, may help decrease overdose-related mortality.
This report follows the evolution of two of the region’s drug policy solutions: its health- and rights-based approach to drug treatment and harm reduction, and its model for safely legalizing the market for cannabis.
Across the globe, the failure of the war on drugs has come at an enormous cost to women. Punitive drug laws and policies pose a heavy burden on women and, in turn, on the children for whom women are often the principal caregivers.
Over the last three decades, the supply side of the worldwide cannabis market has changed significantly. Numerous countries around the world have switched from importing foreign cannabis to domestically producing their own supplies.
Adriana Curado's insight:
"Most harms of cannabis cultivation result from current criminalizing policies."
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