DNA and RNA research
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Using planarian flatworms to understand organ regeneration

Using planarian flatworms to understand organ regeneration | DNA and RNA research | Scoop.it

In a new study published in the October 16 issue of Developmental Cell, corresponding author Professor of Cell and Developmental Biology and Howard Hughes Medical Institute Investigator Phillip Newmark and colleagues report the identification of genes that control growth and regeneration of the intestine in the freshwater planarian Schmidtea mediterranea.

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DNA and RNA research
The latest news and information about DNA- and RNA-related research
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Use of template switching oligos (TS oligos, TSOs) for efficient cDNA library construction

Use of template switching oligos (TS oligos, TSOs) for efficient cDNA library construction | DNA and RNA research | Scoop.it

Conventional cDNA construction strategies usually result in an underrepresentation of the 5' ends of cDNA. However, use of a template switching chimeric DNA:RNA oligo and MMLV reverse transcriptase can improve on this. See how this approach, dubbed SMART, makes it possible to efficiently amplify the entire full-length transcript pool, in a completely sequence-independent manner.

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In a sample of blood, researchers probe for cancer clues

In a sample of blood, researchers probe for cancer clues | DNA and RNA research | Scoop.it

UC Berkeley bioengineers have made an important step towards liquid biopsy technology

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Laser activated gold pyramids could deliver drugs, DNA into cells without harm

Laser activated gold pyramids could deliver drugs, DNA into cells without harm | DNA and RNA research | Scoop.it

Microstructures create temporary pores in cells

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DNA barcoding needed to break fish black market

DNA barcoding needed to break fish black market | DNA and RNA research | Scoop.it

General fish labels like snapper, sole and seabream take away the power to accurately assess stocks and then distort fishing quotas, but by identifying individual species we could prevent illegal catches ending up on our plates. 

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Scientists reveal hidden structures in bacterial DNA 

Scientists reveal hidden structures in bacterial DNA  | DNA and RNA research | Scoop.it

Researchers at the Centre for Genomic Regulation (CRG), have discovered previously unknown arrangements of DNA within extremely small bacteria, publishing their findings in the journal Nature Communications.

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Dramatic evolution within human genome may have been caused by malaria parasite

Dramatic evolution within human genome may have been caused by malaria parasite | DNA and RNA research | Scoop.it

A genetic mutation that protects people from a common form of malaria spread like wildfire in sub-Saharan Africa about 42,000 years ago, according to a new study. Today, it’s nearly impossible to find somebody from this region who doesn’t have it. That makes the mutation one of the swiftest, strongest changes to the human genome yet seen—though it remains a mystery why this particular disease sparked such a dramatic evolutionary response.

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Adapting a DIY robot kit to fill test tubes 

Adapting a DIY robot kit to fill test tubes  | DNA and RNA research | Scoop.it

Modern biology labs often use robotic assemblies to drop precise amounts of fluids into experimental containers. Now students and teachers can create inexpensive automated systems to do this in clubs or classrooms.

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Cut the long story short – and stitch it back together

Cut the long story short – and stitch it back together | DNA and RNA research | Scoop.it

A species of unicellular ciliate has found a special trick to make use of the cellular machinery in seemingly impossible ways. Researchers of the NCCR «RNA & Disease – The Role of RNA Biology in Disease Mechanisms» of the University of Bern have for the first time described a mechanism in detail how so called «junk»-DNA is transcribed before being degraded – and this mechanism is remarkably clever.

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Testing for Zika virus: there’s an app for that

Testing for Zika virus: there’s an app for that | DNA and RNA research | Scoop.it

Sandia prototype dramatically cuts cost, time for detection of mosquito-borne illness

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Cells retain a memory of DNA damage as part of the repair process 

Cells retain a memory of DNA damage as part of the repair process  | DNA and RNA research | Scoop.it

Cells are able to remember that DNA damage has occurred as they pass through the process of cell division, a new study reveals.

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New Software Tools Streamline DNA Sequence Design-and-Build Process

New Software Tools Streamline DNA Sequence Design-and-Build Process | DNA and RNA research | Scoop.it

Improve on existing biological computer-aided design and manufacture (bioCAD/CAM) tools

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Defect in non-coding DNA might trigger brain disorders such as severe language impairment 

Defect in non-coding DNA might trigger brain disorders such as severe language impairment  | DNA and RNA research | Scoop.it

Genetic variation in the non-coding DNA could give rise to language impairments in children and other neurodevelopmental disorders including schizophrenia, autism, and bipolar disorder, scientists from the Max Planck Institute for Psycholinguistics and Radboud University in Nijmegen found. Molecular Psychiatry publishes their work based on a new approach on March 14.

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Reports that cancer is ‘mainly bad luck’ make a complicated story a bit too simple

Reports that cancer is ‘mainly bad luck’ make a complicated story a bit too simple | DNA and RNA research | Scoop.it

New research predicts that 2 in 3 cancers are ‘due to bad luck’, we look at why the story is a bit more complicated than that.

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DNA typos to blame for most cancer mutations

DNA typos to blame for most cancer mutations | DNA and RNA research | Scoop.it

Environment and heredity might not contribute as much to cancer risk as researchers thought.

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DNA Replication Errors Contribute to Cancer Risk 

DNA Replication Errors Contribute to Cancer Risk  | DNA and RNA research | Scoop.it

A follow-up study confirms that random mutations acquired during normal stem cell division likely play a major role in cancer incidence.

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Harvard scientists pinpoint critical step in DNA repair, cellular aging

Harvard scientists pinpoint critical step in DNA repair, cellular aging | DNA and RNA research | Scoop.it

The body’s ability to repair DNA damage declines with age, which causes gradual cell demise, overall bodily degeneration, and greater susceptibility to cancer. Experiments in mice suggest a way to thwart DNA damage.

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Non-invasive prostate cancer diagnosing, monitoring 

Non-invasive prostate cancer diagnosing, monitoring  | DNA and RNA research | Scoop.it

Technology being developed at Washington State University provides a non-invasive approach for diagnosing prostate cancer and tracking the disease’s progression.

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How do metals interact with DNA?

How do metals interact with DNA? | DNA and RNA research | Scoop.it

Since a couple of decades, metal-containing drugs have been successfully used to fight against certain types of cancer. The lack of knowledge about the underlying molecular mechanisms slows down the search for new and more efficient chemotherapeutic agents. An international team of scientists, led by Leticia González from the University of Vienna and Jacinto Sá from the Uppsala University, have developed a protocol that is able to detect how metal-based drugs interact with DNA.

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Defects in non-coding DNA could cause brain disorders

Defects in non-coding DNA could cause brain disorders | DNA and RNA research | Scoop.it

Genetic variation in the non-coding DNA may contribute to language impairments in children and other neurodevelopmental disorders including schizophrenia, autism, and bipolar disorder, scientists from the Max Planck Institute for Psycholinguistics and Radboud University in Nijmegen, Netherlands, found.

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DNA labels predict mortality

DNA labels predict mortality | DNA and RNA research | Scoop.it

Methyl labels in the DNA regulate the activity of our genes and, thus, have a great influence on health and disease. Scientists from the German Cancer Research Center and from the Saarland cancer registry have now revealed that an altered methylation status at only ten specific sites in the genome can indicate that mortality is increased by up to seven times. Smoking has a particularly unfavorable impact on the methylation status.

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Scientists reveal how an ancient biological clock works

Scientists reveal how an ancient biological clock works | DNA and RNA research | Scoop.it

A team of scientists at UC Santa Cruz, UC Merced, and UC San Diego has determined the molecular basis of the cyanobacterial circadian clock, a timing system that synchronizes biological activities with night and day.

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Protein complex that takes first steps in human DNA replication dance is captured at high atomic resolution

Protein complex that takes first steps in human DNA replication dance is captured at high atomic resolution | DNA and RNA research | Scoop.it

A team of biologists co-led by Cold Spring Harbor Laboratory (CSHL) Professor and HHMI Investigator Leemor Joshua-Tor and CSHL President and Professor Bruce Stillman has published pictures at atomic resolution of the multi-part protein complex that performs the very first step in the genome-replication dance.

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Decoding an Elephant’s History to Save Its Future

Decoding an Elephant’s History to Save Its Future | DNA and RNA research | Scoop.it

With a FONZ Conservation Grant, Smithsonian's National Zoo and Conservation Biology Institute scientists are able to understand the family trees of elephants at zoos around the country, as well as answer questions about animal health.

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Scientists reveal new super-fast form of computer that ‘grows as it computes’

Scientists reveal new super-fast form of computer that ‘grows as it computes’ | DNA and RNA research | Scoop.it

Researchers from The University of Manchester have shown that it is possible to build a new super-fast form of computer that “grows as it computes”.

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Genome-based diets maximize growth, fecundity, and lifespan

Genome-based diets maximize growth, fecundity, and lifespan | DNA and RNA research | Scoop.it

A new developed diet for fruit flies increases growth and fecundity without shortening life-span

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