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DNA & RNA Research
The latest news and information about DNA- and RNA-related research
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The Gene Construction Revolution

The Gene Construction Revolution | DNA & RNA Research | Scoop.it
How Custom, Double-Stranded DNA is Replacing High Quality Long Oligos
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Throwing a loop to silence gene expression

Throwing a loop to silence gene expression | DNA & RNA Research | Scoop.it

Cells attach so-called ‘epigenetic’ signals to their genome to select which part of their genetic information is used. Scientists from the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) have now systematically investigated the interplay between components of an epigenetic network and developed a mathematical model that describes how it operates. The results can be used to predict how cellular gene expression programs respond to drug treatment or other perturbations of the cellular environment.

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Researchers examine disease-causing mutations in mitochondrial genomes

Researchers examine disease-causing mutations in mitochondrial genomes | DNA & RNA Research | Scoop.it

The study of genetic disease has often centered on the human nuclear genome - the sprawling linear code of about 3.2 billion nucleotides and more than 24,000 genes spread across our 46 chromosomes. In contrast, the other genome that resides within us, the mitochondrial genome, has received less attention. Though our genome dwarfs it in size - a short, circular genome with just over 16,000 nucleotides and exactly 37 genes - the small (but mighty) mitochondria genome is arguably just as important.

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Discovery reveals how bacteria distinguish harmful versus helpful viruses

Discovery reveals how bacteria distinguish harmful versus helpful viruses | DNA & RNA Research | Scoop.it

When they are not busy attacking us, germs go after each other. But when viruses invade bacteria, it doesn’t always spell disaster for the infected microbes: Sometimes viruses actually carry helpful genes that a bacterium can harness to, say, expand its diet or better attack its own hosts.

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‘Gene Surgery’ cures disease in mammals

‘Gene Surgery’ cures disease in mammals | DNA & RNA Research | Scoop.it

Biologists have now used CRISPR/Cas9 to edit the genome of mice with muscular dystrophy. 

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New research reveals the genetic basis for animal domestication out of a rabbit hole

New research reveals the genetic basis for animal domestication out of a rabbit hole | DNA & RNA Research | Scoop.it

Published today in leading publication Science, TGAC’s Director of Science Federica Di Palma, with an international team of scientists, leads ground-breaking study examining the domestication of rabbits. The research presents key findings in the DNA make-up of the common mammal’s brain and nervous system, which determines how wild rabbits were genetically transformed to domestic rabbits. The study predicts a similar diversity of gene variants that occur in humans and triggers our personality traits.

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DNA tells story of Arctic peopling

DNA tells story of Arctic peopling | DNA & RNA Research | Scoop.it

A new "genetic prehistory" provides the best picture ever assembled of how the North American Arctic was populated, from 6,000 years ago to the present.

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Newly Approved DNA Test for HPV Could Replace Your Pap

Newly Approved DNA Test for HPV Could Replace Your Pap | DNA & RNA Research | Scoop.it

Most women would rather avoid a Pap test that isn’t necessary — and now they can. Recently, the FDA approved the HPV DNA test that can be used as a stand-alone test without a Pap smear. This test, which has been approved for women age 25 and older, gives your gynecologist another tool for diagnosing cervical cancer. The test was approved by the FDA in April, but has been available for several years. 

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Researching Fundamental Rhythms of Life

Researching Fundamental Rhythms of Life | DNA & RNA Research | Scoop.it

Evolution has harmonized the behavior of humans and all other mammals with fundamental rhythms of life that include the cycle of light and dark experienced each day and with seasonal change. The brain’s circadian clock controls hormone production related to natural patterns of sleep/wake behavior which, when disrupted by experiences such as jet lag or night-shift work, can have adverse health effects. It’s a vital physiological process intrinsic to our mood and alertness, but one that has yet to be fully understood.

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Discovering a new superfamily of DNA transposons: Cas gets in on the action

Discovering a new superfamily of DNA transposons: Cas gets in on the action | DNA & RNA Research | Scoop.it

Cas enzymes and their associated CRISPR RNAs have hit the biotech headlines recently as tools for genome editing. However, they have a natural function, too: an immunity system for prokaryotes that defends the genome by cutting and pasting foreign DNA into ‘memory’. In a bioinformatics study published in BMC Biology, Eugene Koonin from the National Center for Biotechnology Information, USA, Mart Krupovic from the Institut Pasteur, France, and colleagues identify yet another function of Cas enzymes – the instigators of mobility in a class of transposons, which they name ‘casposons’.

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Cancer Leaves a Common Fingerprint on DNA

Cancer Leaves a Common Fingerprint on DNA | DNA & RNA Research | Scoop.it

Chemical alterations to genes appear key to tumor development

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Momentum Builds To Keep Fraudulent Food Off Of Store Shelves

Momentum Builds To Keep Fraudulent Food Off Of Store Shelves | DNA & RNA Research | Scoop.it

Faced with mounting scandals, food industry looks for ways to prevent the next one from happening

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New technique accelerates genome editing process

New technique accelerates genome editing process | DNA & RNA Research | Scoop.it

It sounds like a potato chip. But CRISPR is actually the acronym for a new genome editing technique that, by many accounts, is accelerating the study of genes and disease.

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Genome Editing Rewrites the Future of Dairy Cattle

Genome Editing Rewrites the Future of Dairy Cattle | DNA & RNA Research | Scoop.it

Can genome-editing technology revive the idea of genetically modified livestock?

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The Second Coming of RNAi

The Second Coming of RNAi | DNA & RNA Research | Scoop.it

Now showing clinical progress against liver diseases, the gene-silencing technique begins to fulfill some of its promises.

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Tiny, Vast Windows Into Human DNA

Tiny, Vast Windows Into Human DNA | DNA & RNA Research | Scoop.it

In the fruit fly and the worm Caenorhabditis elegans, scientists have found a choreography of genes strikingly similar to human DNA, with the potential for insights into genetic disorders.

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DNA May Have Had Humble Beginnings As Nutrient Carrier

DNA May Have Had Humble Beginnings As Nutrient Carrier | DNA & RNA Research | Scoop.it

New research intriguingly suggests that DNA, the genetic information carrier for humans and other complex life, might have had a rather humbler origin. In some microbes, a study shows, DNA pulls double duty as a storage site for phosphate. This all-important biomolecule contains phosphorus, a sometimes hard-to-get nutrient. 

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Ancient DNA Could Return Passenger Pigeons to the Sky

Ancient DNA Could Return Passenger Pigeons to the Sky | DNA & RNA Research | Scoop.it

Genetic engineering could restore the once profuse North American bird after a century or more of extinction

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How silent genes are activated

How silent genes are activated | DNA & RNA Research | Scoop.it

DNA methylation is a dynamic and reversible process that governs gene expression during development and disease.

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Nanoscale assembly line

Nanoscale assembly line | DNA & RNA Research | Scoop.it

ETH researchers have realised a long-held dream: inspired by an industrial assembly line, they have developed a nanoscale production line for the assembly of biological molecules.

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Scientists looking across human, fly and worm genomes find shared biology

Scientists looking across human, fly and worm genomes find shared biology | DNA & RNA Research | Scoop.it

Researchers analyzing human, fly, and worm genomes have found that these species have a number of key genomic processes in common, reflecting their shared ancestry. The findings, appearing Aug. 28, 2014, in the journal Nature, offer insights into embryonic development, gene regulation and other biological processes vital to understanding human biology and disease. 

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No-frills coats set a trend for designer viruses

No-frills coats set a trend for designer viruses | DNA & RNA Research | Scoop.it

An artificial protein that self-assembles around and protects DNA could be ideal for gene therapy, nanomachines and synthetic biology

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Bowel disease gene discovery

Bowel disease gene discovery | DNA & RNA Research | Scoop.it

Scientists have identified chemical changes in the DNA of patients with Crohn’s disease that could help to screen people for the disease.

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Revolutionary handheld DNA diagnostic unit allows lab-quality analysis in the field

Revolutionary handheld DNA diagnostic unit allows lab-quality analysis in the field | DNA & RNA Research | Scoop.it

A revolutionary handheld and battery-powered DNA diagnostic device invented at the University of Otago is poised to become a commonly used field tool for rapidly detecting suspected viruses or bacteria in samples while also determining the level of infection.

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Finding Fingerprints of Selection in Poplar Genomes

Jerry Tuskan of Oak Ridge National Laboratory and the DOE JGI talks about poplar trees as models for selective adaptation to an environment. This video complements a study published ahead online August 24, 2014 in Nature Genetics.

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Signatures of Selection Inscribed on Poplar Genomes

Signatures of Selection Inscribed on Poplar Genomes | DNA & RNA Research | Scoop.it

Genome-Wide Study Shows Evidence of Genetic Selection

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