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Statins linked to muscle pain, sprains | Reuters

Statins linked to muscle pain, sprains | Reuters | Disease mongering | Scoop.it
NEW YORK (Reuters Health) - Cholesterol-lowering drugs could be tied to more muscle problems than researchers previously believed, a new study hints.Researchers compared two groups of similar people enrolled...
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Disease mongering
Overdiagnosis of disease: a modern epidemic sickness.
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MSD minaccia azioni legali per far cessare le critiche ad un suo prodotto. Pillole.org

La MSD ha minacciato azioni legali contro l'epidemiologo clinico Alberto Donzelli, per indurlo a cessare di esprimere critiche nei confronti dell'uso di un prodotto dell'azienda. 

Assume connotati internazionali la controversia tra la Merck Sharp & Dohme e il Dottor Alberto Donzelli, responsabile appropriatezza clinica della ASL di Milano. Il BMJ ha pubblicato un articolo che riassume la vicenda.

La filiale italiana della compagnia farmaceutica Merck Sharp & Dohme (MSD) ha stoppato un medico di primo piano nella gestione della salute pubblica intimandogli di cessare di indirizzare ai Medici di Medicina Generale testi medici critici nei confronti dell'uso di uno dei farmaci della società. 

Nei testi, Alberto Donzelli, il capo della formazione, appropriatezza e medicina basata sulle evidenze presso l'azienda di sanità pubblica di Milano (ASL Milano), aveva analizzato le prove pubblicate sul farmaco ezetimibe scoraggiandone l'uso in aggiunta alle statine. 

Una lettera a "cessare e desistere" è stata inviata in febbraio dal direttore medico di MSD, Patrizia Nardini, ed è stata recapitata dal direttore degli affari legali della società. Hanno accusato Donzelli di colpa grave e di una violazione dell'etica medica e minacciato di far causa a lui e a Milano Sanità per una cifra di € 1,3 milioni (1 milione di sterline; $ 1.78m). La lettera era indirizzata a Donzelli, con copia inviata al direttore generale della ASL di Milano e al presidente dell'Ordine dei Medici di Milano Roberto Carlo Rossi.  aggiornamento, ricerca, supporto, promozione del ruolo dei medici.
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Sugar: A Love/Hate Relationship. Why We Can't Ever Give Up The Sweet Stuff

Sugar: A Love/Hate Relationship. Why We Can't Ever Give Up The Sweet Stuff | Disease mongering | Scoop.it
The growing list of evils in almost any product is hard to keep track of. First it was fat. Then it was carbs, trans-fat. Then high fructose corn syrup. Salt: It’s bad!
Now it’s sugar.
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Higher glucose levels associated with lower memory and reduced hippocampal microstructure

Higher glucose levels associated with lower memory and reduced hippocampal microstructure | Disease mongering | Scoop.it

Editors' Note: Grabenhenrich and Roll critique the methodology and design in the study by Kerti et al. on the association between glucose metabolism and memory performance. The authors conduct additional statistical analysis to support their results. Neurology's sometime neuromythologist and historian, William Landau, cites quotations from Parkinson's historical monograph to comment on the article by Bohnen et al. on gait speed in Parkinson disease. The authors respond.—Chafic Karam, MD, and Robert C. Griggs, MD

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Routine prostate cancer screening 'reduces deaths but leads to overdiagnosis'

Routine prostate cancer screening 'reduces deaths but leads to overdiagnosis' | Disease mongering | Scoop.it
Long-term results of a major European study reveal that prostate cancer screening reduces deaths by more than 20%, but researchers say it is still too soon for routine screening.
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Self service, quando il consumatore finisce per lavorare - Nuove abitudini - Società - Lifestyle

Self service, quando il consumatore finisce per lavorare - Nuove abitudini - Società - Lifestyle | Disease mongering | Scoop.it
Addio al vecchio capitalismo, adesso c'è il 'prosumerismo', termina che accorpa produttori di lavoro e consumatori in un identico sfruttamento. A teorizzarlo è il sociologo dell'Università del Maryland George Ritzer, che sull'argomento ha tenuto una relazione al Futura Festival di Civitanova Marche (Macerata)
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New York’s Ban on Big Sodas Is Rejected by Final Court - NYT - #diseasemongering

New York’s Ban on Big Sodas Is Rejected by Final Court - NYT - #diseasemongering | Disease mongering | Scoop.it
The State Court of Appeals declined to reinstate New York City’s limits on sales of jumbo sugary drinks, exhausting the city’s legal options.
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Financial relationships between the pharmaceutical industry and physicians have come under increased scrutiny. Less attention has been paid to relationships between industry and the leadership of a...

Financial relationships between the pharmaceutical industry and physicians have come under increased scrutiny. Less attention has been paid to relationships between industry and the leadership of a... | Disease mongering | Scoop.it

Financial relationships between the pharmaceutical industry and physicians have come under increased scrutiny. Less attention has been paid to relationships between industry and the leadership of academic medical centers (AMCs), who wield considerable influence over research, clinical, and educational missions.

When AMC leaders serve on pharmaceutical company boards, they hold a fiduciary responsibility to shareholders to promote the financial success of the company, which may conflict or compete with institutional oversight responsibilities and individual clinical and research practices.1 The potential conflict between responsibilities of individuals who hold leadership roles in both industry and academia deserves exploration.

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Medicina: la libertà di cura è libertà di farsi truffare? - Il Fatto Quotidiano

Medicina: la libertà di cura è libertà di farsi truffare? - Il Fatto Quotidiano | Disease mongering | Scoop.it
La libertà di cura è un fondamento di una società civile. Libertà di come curare la propria salute significa che ogni individuo deve essere libero di accet
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Le mercantilisme menace les communautés de pati...

Le mercantilisme menace les communautés de pati... | Disease mongering | Scoop.it

Tribune. Un groupe de responsables d’associations de malades s’inquiète du détournement mercantile de réseaux conçus à l’origine comme des outils de démocratie sanitaire.


Via Guillaume de DURAT, LA BLOUSE BLANCHE
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Glaxo to Stop Paying Doctors for Drug Promotion | Health Impact News

Glaxo to Stop Paying Doctors for Drug Promotion | Health Impact News | Disease mongering | Scoop.it
Drug giant GlaxoSmithKline has announced it will no longer pay health care professionals to promote its products or the diseases they treat to “audiences who can prescribe or influence prescribing.” Glaxo also plans to stop compensating its sales...

Via Lionel Reichardt / le Pharmageek
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MSD Italy is criticised for threatening legal action over prescription advice to GPs

The Italian branch of the drug company Merck Sharp and Dohme (MSD) has stopped a leading public health doctor and administrator from circulating texts to GPs advising them about the use of one of the company’s drugs.

In the texts, Alberto Donzelli—the head of education, appropriateness, and evidence based medicine at the public health authority of Milan (Milan Healthcare)—had analysed the published evidence on the cholesterol lowering drug ezetimibe and discouraged its prescription in addition to statins.

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Confessions of an Rx Drug Pusher [Kindle]

Confessions of an Rx Drug Pusher [Kindle] | Disease mongering | Scoop.it
This is the story of Gwen Olsen. Once a very successful pharmaceutical sales rep., now her mission is to stop the over-medication of our children. Gwen is th...
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Researcher who falsified HIV results pleads not guilty in US court

A researcher who spiked rabbit blood with human antibodies to make it appear that an experimental HIV vaccine worked has pleaded not guilty to fraud in a US federal court, despite previously admitting his acts in a resignation letter to his university.

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Pfizer agrees to pay $35 million for improper marketing of Rapamune

Pfizer agrees to pay $35 million for improper marketing of Rapamune | Disease mongering | Scoop.it
US pharma giant Pfizer has reached a $35 million settlement with 41 states in the USA and the District of Columbia for improper marketing and promotion of the i
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Dabigatran: how the drug company withheld important analyses

Dabigatran: how the drug company withheld important analyses | Disease mongering | Scoop.it

In an investigation by The BMJ Deborah Cohen finds that recommendations for use of new generation oral anticoagulants may be flawed because regulators did not see evidence showing that monitoring drug plasma levels could improve safety

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Plus du quart des césariennes pourraient être évitées

Plus du quart des césariennes pourraient être évitées | Disease mongering | Scoop.it

D'après cinq chercheurs, dont deux de l'Institut national de la santé et de la recherche médicale, 28 % d'entre elles en France auraient pu être évitées.


Via Giovanna Marsico
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Vaincre le conflit d’intérêts médical, par Irène Frachon et Pierre Le Coz

Vaincre le conflit d’intérêts médical, par Irène Frachon et Pierre Le Coz | Disease mongering | Scoop.it
Après le scandale du Mediator et le décès de Jacques Servier, une page se tourne dans le combat pour la transparence, mais il reste encore beaucoup à faire

Via Renaloo, EVELYNE PIERRON
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Renaloo's curator insight, August 6, 3:59 AM

Le décret d’application de la loi Bertrand traduisant la nécessité de rendre les liens transparents, en référence au Physician Sunshine Act adopté aux Etats-Unis en 2010, qui, comme son nom l’indique [sunshine signifie « éclat du soleil »], oblige à mettre au jour les liens d’intérêt des médecins américains. Le décret français reste cependant loin des ambitions initiales : seule une transparence limitée entre médecins et laboratoires pharmaceutiques à la déclaration chiffrée de quelques « plateaux repas » et autres cadeaux dits « sans contrepartie » a été imposée, laissant dans l’ombre les montants de contrats juteux liant l’industrie pharmaceutique à des médecins-relais qui assurent la promotion de ses nouveaux produits.

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Online Medical Advice Can Be a Prescription for Fear

Online Medical Advice Can Be a Prescription for Fear | Disease mongering | Scoop.it
Despite the Mayo Clinic site’s credibility, symptom addicts still use WebMD.
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HIV Drug Companies Staged "Bidding War" Over Kickbacks to Doctors, Suit Says

HIV Drug Companies Staged "Bidding War" Over Kickbacks to Doctors, Suit Says | Disease mongering | Scoop.it
The complaint suggests corrupt practices at one company can create instant incentives that force competing companies to respond, engulfing an entire category.
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Top 10 downloaded iPhone health app can cause significant patient harm - iMedicalApps

Top 10 downloaded iPhone health app can cause significant patient harm - iMedicalApps | Disease mongering | Scoop.it
How a popular iPhone health app is being used by patients incorrectly to monitor blood pressure

I was going through the Apple App Store’s Health & Fitness category last week, when I noticed an interesting health app that had made it into the top 10 “Paid” and “Top Grossing” sections.1  The app’s name is: “Instant Blood Pressure — Monitor Blood Pressure Using Only Your iPhone”.

The following screen shots show the initial description you get of the app in iTunes or your iPhone.

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HARMFUL MEDICAL OVERUSE - Italy’s “Doing more does not mean doing better campaig

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Patient digitalisé ou manipulé? - Editorial - Focus - InVivo

Patient digitalisé ou manipulé? - Editorial - Focus - InVivo | Disease mongering | Scoop.it

Via Lionel Reichardt / le Pharmageek, LA BLOUSE BLANCHE
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Ces médecins qui tissent des liens avec les laboratoires pharmaceutiques sont-ils influençables…Et influencés ?

Ces médecins qui tissent des liens avec les laboratoires pharmaceutiques sont-ils influençables…Et influencés ? | Disease mongering | Scoop.it

Ces médecins qui tissent des liens avec les laboratoires pharmaceutiques sont-ils influençables…Et influencés ?

Lorsqu’on les interroge sur leurs multiples liens et conflits d’intérêts avec les grands labos et les scandales sanitaires dus à certains médicaments, ces leaders d’opinion se vexent, et deviennent même agressifs pour certains. Ils s’estiment totalement indépendants et persuadés de n’être en rien influençables...


Via Michel Delon, Lionel Reichardt / le Pharmageek
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Michel Delon's curator insight, October 19, 2013 3:51 PM
Quels avantages ou bénéfices récoltent ces leaders d’opinion pour répandre de fausses informations ?
sylvie Royant-Parola's comment, October 20, 2013 10:26 AM
Cet article est une caricature... Que de telles situations aient existé, surement, mais depuis plus de 10 ans elles sont l'exception. Les labos nous ont aidé sur 3 plans, le financement de participation à des congrès, et je peux vous assurer que ce ne sont pas des vacances, même si on peut utiliser une après midi pour découvrir la ville où on est. Grâce à ces congrès et aux invitations par les labos il y a eu de vrais échanges au sein de la communauté des chercheurs ou des cliniciens, avec souvent à la clé des coopérations de recherche ou de réseaux qui sont nés. Le deuxième volet du financement touche les dons aux associations qui ont permis ce que la rigidité des instituions ne permet pas : la mise en route de protocoles, le tenue de registre, l’achat de matériel, le financement d’un poste de chargé de mission pendant quelques mois… Enfin le troisième volet touche la formation, pour payer le déplacement des intervenants (qui interviennent le plus souvent bénévolement), les salles de réunions, et plus globalement la logistique. Pour quelques abus, on suspecte et embête toute une profession Il ne faut pas oublier que l’exercice médical, surtout en libéral, est très solitaire. Or nous avons besoin d’échanger entre nous, de faire du lien à la fois pour maintenir nos connaissances mais aussi pour notre moral. Les labos ont joué ce rôle. Attention de ne pas tout démolir. Un médecin triste est un médecin dangereux !
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Corruption: medicine’s dirty open secret | BMJ

Corruption: medicine’s dirty open secret | BMJ | Disease mongering | Scoop.it
NotesCite this as: BMJ 2014;348:g4184 ("Healthcare is a high risk sector for corruption. Best estimates are that between 10% and 25% of global spend on...

Via Family Doctor, Lionel Reichardt / le Pharmageek
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#pilloleamare: cosa stiamo imparando? | dottprof.com

#pilloleamare: cosa stiamo imparando? | dottprof.com | Disease mongering | Scoop.it
Alberto Donzelli è una persona perbene che da anni cura - per il servizio di educazione all'appropriatezza e medicina basata sulle evidenze della ASL di Milano
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Lo strano caso del dottor Donzelli e del Signor MSD | Partecipasalute.it

Lo strano caso del dottor Donzelli e del Signor MSD | Partecipasalute.it | Disease mongering | Scoop.it


Pillole è una rivista di informazione curata dal Servizio educazione alla Appropriatezza ed EBM (medicina basata sulle prove) della ASL di Milano. In seguito ad un articolo su un farmaco ha ricevuto da una azienda farmaceutica una richiesta di risarcimento danni.

I referenti delle riviste ISDB (*) hanno sottoscritto una lettera di sostegno all’attività di questa rivista nel pubblicare informazioni basate sulle prove, spingendo altresì ad un confronto costruttivo sui dati e non alla sterile querelle legale. Vi invitiamo a leggere la lettera, a sostenerla e farla girare. http://www.slideshare.net/sfwebm/lo-strano-caso-del-dr-donzelli-finale-2...

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