Our capacity to partner with biology to make useful things is limited by the tools that we can use to specify, design, prototype, test, and analyze natural or engineered biological systems. However, biology has typically been engaged as a "technology of last resort" in attempts to solve problems that other more mature technologies cannot. This lecture will examine some recent progress on virus genome redesign and hidden DNA messages from outer space, building living data storage, logic, and communication systems, and how simple but old and nearly forgotten engineering ideas are helping make biology easier to engineer.

Via Szabolcs Kósa, Dr. Stefan Gruenwald, John Purificati