German researchers Ed Gronenschild and colleagues took a set of 30 brains and got FreeSurfer to estimate the size and thickness of various structures. Then they did the same thing, on the exact same brains, with a different version of the software.
They found substantial differences in regional volumes, depending upon the version of FreeSurfer used. Running the same version of the software on a Mac vs a PC also created differences, and even the version of Mac OS had an impact.
Via Sakis Koukouvis