I found an awesome website that has over 100 early readers with audio! The site is Unite For Literacy and I took the first 50 of the books and created a Symbaloo webmix for my class. The best part is these books work on the iPad as well! I will make another webmix of 50 more books soon.
Jewish Quarter of Old City to become wheelchair accessible Jerusalem Post. A NIS 20 million initiative spearheaded by the Jerusalem Municipality, Bituach Leumi and the Jerusalem Development Authority will make the Jewish Quarter in the Old City and...
Japanese researchers have created an “artificial neural connection” (ANC) from the brain directly to the spinal locomotion center in the lower thoracic and lumbar regions of the spine, potentially one day allowing patients with spinal-cord damage, such as paraplegics, to walk.
The study led by Shusaku Sasada, research fellow, and Yukio Nishimura, associate professor, both of the National Institutes of Natural Sciences (NINS), was published online in The Journal of Neuroscience on August 13, 2014.
Neural networks called “central pattern generators” (see Ref. 2 and 3 below) in the locomotion center (lower than the lesion site) are capable of producing rhythmic movements, such as walking, even when isolated from the brain, the researchers suggest.
The researchers worked with neurologically intact subjects who are were asked to allow the computer to passively control their leg movements.
As a surrogate, the researchers used muscle signals normally generated by the arm movements associated with leg movements. These signals were used to control a computer-driven magnetic device that non-invasively (externally) stimulated neurons in the spinal locomotion center.
Additional simultaneous peripheral electrical stimulation to the foot via the ANC enhanced this walking-like behavior. Kinematics of the induced behaviors were identical to those observed in normal voluntary walking. The researchers said they are planning clinical studies in the near future.
Last week, the federal government revealed that it will fine more than 2,600 hospitals in the coming year, because too many Medicare patients treated at these hospitals are ending up back in the hospital within 30 days of going home. Two new conditions have been added in this round of penalties: elective hip and knee replacement, and chronic lung disease.
There have been many ground-breaking introductions of adaptive ski equipment over the years. The first ski outriggers were created around 1970. These were followed by a list of other game-changing devices in the sport including the ski bra in 1974, which prevents ski tips from crossing, the first sit ski in 1978 and the mono ski in 1984.
"The iPhone and iPad come equipped with some great accessibility features that open the door to all kinds of functionality for those with hearing and visual impairments. One especially useful feature for those with auditory impairments is the ability to pair their iPhone or iPad with many supported hearing aids. There are even some hearing aids that carry the made for iPhone moniker so you know your experience will be seamless. To get started, you've just got to pair them together! "
Injuries, birth defects (such as cleft palates) or surgery to remove a tumor can create gaps in bone that are too large to heal naturally. And when they occur in the head, face or jaw, these bone defects can dramatically alter a person's appearance. Researchers will report today that they have developed a "self-fitting" material that expands with warm salt water to precisely fill bone defects, and also acts as a scaffold for new bone growth.
Currently, the most common method for filling bone defects in the head, face or jaw (known as the cranio-maxillofacial area) is autografting. That is a process in which surgeons harvest bone from elsewhere in the body, such as the hip bone, and then try to shape it to fit the bone defect.
"The problem is that the autograft is a rigid material that is very difficult to shape into these irregular defects," says Melissa Grunlan, Ph.D., leader of the study. Also, harvesting bone for the autograft can itself create complications at the place where the bone was taken. Another approach is to use bone putty or cement to plug gaps. However, these materials aren't ideal. They become very brittle when they harden, and they lack pores, or small holes, that would allow new bone cells to move in and rebuild the damaged tissue.
To develop a better material, Grunlan and her colleagues at Texas A&M University made a shape-memory polymer (SMP) that molds itself precisely to the shape of the bone defect without being brittle. It also supports the growth of new bone tissue.
SMPs are materials whose geometry changes in response to heat. The team made a porous SMP foam by linking together molecules of poly(ε-caprolactone), an elastic, biodegradable substance that is already used in some medical implants. The resulting material resembled a stiff sponge, with many interconnected pores to allow bone cells to migrate in and grow. Upon heating to 140 degrees Fahrenheit, the SMP becomes very soft and malleable. So, during surgery to repair a bone defect, a surgeon could warm the SMP to that temperature and fill in the defect with the softened material. Then, as the SMP is cooled to body temperature (98.6 degrees Fahrenheit), it would resume its former stiff texture and "lock" into place.
The researchers also coated the SMPs with polydopamine, a sticky substance that helps lock the polymer into place by inducing formation of a mineral that is found in bone. It may also help osteoblasts, the cells that produce bone, to adhere and spread throughout the polymer. The SMP is biodegradable, so that eventually the scaffold will disappear, leaving only new bone tissue behind. To test whether the SMP scaffold could support bone cell growth, the researchers seeded the polymer with human osteoblasts. After three days, the polydopamine-coated SMPs had grown about five times more osteoblasts than those without a coating. Furthermore, the osteoblasts produced more of the two proteins, runX2 and osteopontin, that are critical for new bone formation.
Grunlan says that the next step will be to test the SMP's ability to heal cranio-maxillofacial bone defects in animals. "The work we've done in vitro is very encouraging," she says. "Now we'd like to move this into preclinical and, hopefully, clinical studies."
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