Italian biopharmaceutical company Dompé today announced the launch of REP0112, a randomized double-blind multicenter Phase II/III trial to assess the efficacy and safety of Reparixin in autologous islet cell transplantation, a procedure where,...
First-line treatment with sulfonylureas instead of metformin in people with type 2 diabetes is associated with a significantly elevated risk of death, according to results from an observational study presented at the European Association for the...
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WA, Seattle (September 23, 2013) – Encouraging results from the T1DAL study (Targeting effector memory T cells with alefacept in new onset type 1 diabetes), led by Mark R. Rigby M.D., Ph.D.
Ellen H Ullman, MSW's insight:
What are the possible side effects of alefacept (Amevive)?
Alefacept reduces levels of certain white blood cells in the body. If the level of these white blood cells falls too low, treatment with alefacept may need to be withheld temporarily or discontinued. Your doctor will monitor your white blood cell levels during treatment.
Alefacept may increase the risk of developing cancer. Do not use alefacept without first talking to your doctor if you have cancer or a history of cancer.
Alefacept reduces certain actions of the immune system and may increase the risk of developing a new infection or reactivating a chronic infection that has been latent (inactive). Contact your doctor immediately if you develop symptoms of an infection such as fever or chills, sore throat, coughing, or burning with urination.
Stop using alefacept and seek emergency medical attention if you develop symptoms of an allergic reaction such as difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives.
Other less serious side effects may be more likely to occur. Continue to use alefacept and talk to your doctor if you experience
sore throat or cough;dizziness;headachenausea;itching;muscle aches;chills; orpain, discomfort, or inflammation at the injection site.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.
More than a year after drugmakers began jousting over names for biosimilars, the trade group for generic drugmakers has taken the formal step of filing a citizen’s petition with the FDA to request that all such products share the same international...
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Five-year-old Jillian Given wasn't rattled.In what authorities describe as "calm and collected" fashion, the Ronkonkoma girl made a 911 call last week that officials say saved her mother's life."My mo...
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