Devil Facial Tumour Disease
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DPIPWE - Tasmanian Devil Facts for Kids

DPIPWE - Tasmanian Devil Facts for Kids | Devil Facial Tumour Disease | Scoop.it
Facts about Tassie devils, written for kids. Information about their eating habits, life cycle and other interesting details.

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Megan Klein's curator insight, December 23, 2012 12:11 AM

Tasmanian Devil

1. Eaing Habits

2. Life Cycle

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Tasmanian devils born in NSW

Tasmanian devils born in NSW | Devil Facial Tumour Disease | Scoop.it
The Tasmanian devil may be fighting for survival in its native home, but their numbers are booming in NSW.

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Alexis La Rosa's comment, February 22, 2013 3:59 PM
Even if the urge to kill the predator eating our livestock can sometimes skyrocket, that's not always the best course of action. Preserving the natural predators of the wild is important.
And so, it is with that in mind, that efforts are being made to save Tasmanian Devils. A disease, a facial tumor, might be what's causing this widespread death instead of angry farmers, but the principle stands.
Devil's Ark, in New South Wales, is running a program to help supplement, or even replace if the species, unfortunately, becomes extinct, the Tasmanian Devil's population in Tasmania as soon as the disease clears.
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Tasmanian Devil Cancer Traced Back to 'Immortal' Devil Girl | Tasmanian Devil, Transmissible Cancer & Cancer Genetics | LiveScience

Tasmanian Devil Cancer Traced Back to 'Immortal' Devil Girl | Tasmanian Devil, Transmissible Cancer & Cancer Genetics | LiveScience | Devil Facial Tumour Disease | Scoop.it
Researchers have sequenced the genomes of both the Tasmanian devil and the very unique transmissible cancer that's killing it.

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Tasmanian Devils Are Being Shipped To A Private Island To Save Them From Extinction

Tasmanian Devils Are Being Shipped To A Private Island To Save Them From Extinction | Devil Facial Tumour Disease | Scoop.it
Tasmanian devil populations will be relocated to Maria Island to save them from the deadly cancer that's killing off their main population.

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Hopes of a tumour test for Tasmanian devils : Nature News

Nature - the world's best science and medicine on your desktop...

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Fighting a contagious cancer - Elizabeth Murchison

What is killing the Tasmanian devil? A virulent cancer is infecting them by the thousands -- and unlike most cancers, it's contagious. Researcher Elizabeth M...

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Devil Ark: saving the Tassie devil

Devil Ark: saving the Tassie devil | Devil Facial Tumour Disease | Scoop.it

An hour’s drive north of Sydney, Devil Ark is doing its all to save the endangered Tasmanian devil. It’s a new conservation program of the Australian Reptile Park, and it’s creating an insurance population of healthy, genetically diverse devils that can be reintroduced to Tasmania once the devastating DFTD disease has run its course. It’s an ambitious program, and they could do with your elbow grease or back-of-the-sofa coins.


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Cull 'no help' to Tasmanian devil - BBC News

Cull 'no help' to Tasmanian devil - BBC News | Devil Facial Tumour Disease | Scoop.it
BBC NewsCull 'no help' to Tasmanian devilBBC NewsThe study, in the Journal of Applied Ecology, seems to confirm findings in wild trials, that selective culling of sick animals is ineffectual at stopping the spread of the disease.

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Devil Ark: saving the Tassie devil

Devil Ark: saving the Tassie devil | Devil Facial Tumour Disease | Scoop.it

An hour’s drive north of Sydney, Devil Ark is doing its all to save the endangered Tasmanian devil. It’s a new conservation program of the Australian Reptile Park, and it’s creating an insurance population of healthy, genetically diverse devils that can be reintroduced to Tasmania once the devastating DFTD disease has run its course. It’s an ambitious program, and they could do with your elbow grease or back-of-the-sofa coins.


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Australia's Tasmanian devils to get fresh start free of facial infectious tumor on new island

Australia's Tasmanian devils to get fresh start free of facial infectious tumor on new island | Devil Facial Tumour Disease | Scoop.it

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Tasmanian Devils fight hardest battle yet | Nature | The Earth Times

Tasmanian Devils fight hardest battle yet | Nature | The Earth Times | Devil Facial Tumour Disease | Scoop.it
Greens claim funding decision will condemn Tasmanian Devils to extinction
ABC Online
The Australian Greens claim a federal government funding decision will condemn the Tasmanian devil to extinction.

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Hope for threatened Tasmanian devils: Research paves way for vaccine development

Hope for threatened Tasmanian devils: Research paves way for vaccine development | Devil Facial Tumour Disease | Scoop.it
Greens claim funding decision will condemn Tasmanian Devils to extinction
ABC Online
The Australian Greens claim a federal government funding decision will condemn the Tasmanian devil to extinction.

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Tasmanian devils to be released back on to mainland

Tasmanian devils to be released back on to mainland | Devil Facial Tumour Disease | Scoop.it
Greens claim funding decision will condemn Tasmanian Devils to extinction
ABC Online
The Australian Greens claim a federal government funding decision will condemn the Tasmanian devil to extinction.
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DPIPWE - Tasmanian Devil Facts for Kids

DPIPWE - Tasmanian Devil Facts for Kids | Devil Facial Tumour Disease | Scoop.it
Facts about Tassie devils, written for kids. Information about their eating habits, life cycle and other interesting details.

Via Megan Klein, Parveen
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Megan Klein's curator insight, December 23, 2012 12:11 AM

Tasmanian Devil

1. Eaing Habits

2. Life Cycle

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DPIPWE - Tasmanian Devil Facts for Kids

DPIPWE - Tasmanian Devil Facts for Kids | Devil Facial Tumour Disease | Scoop.it
Facts about Tassie devils, written for kids. Information about their eating habits, life cycle and other interesting details.

Via Megan Klein
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Megan Klein's curator insight, December 23, 2012 12:11 AM

Tasmanian Devil

1. Eaing Habits

2. Life Cycle

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The Desperate Fight to Save the Tasmanian Devil from Extinction

The Desperate Fight to Save the Tasmanian Devil from Extinction | Devil Facial Tumour Disease | Scoop.it
Thanks to an unusual, unrelenting and contagious cancer, the global population of tasmanian devils is declining at an alarming rate, and the only way to save them seems to be removing the animals from their eponymous island.

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Tasmanian Devils Might Survive Cancer Scourge - Wired News

Tasmanian Devils Might Survive Cancer Scourge - Wired News | Devil Facial Tumour Disease | Scoop.it
ZME ScienceTasmanian Devils Might Survive Cancer ScourgeWired NewsMcCallum is, along with his co-authors on an Oct.

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40 baby Tasmanian devils born - sparking new hope ... - ZME Science

40 baby Tasmanian devils born - sparking new hope ... - ZME Science | Devil Facial Tumour Disease | Scoop.it

Tasmanian devils are having the fight of their lives against Devil Facial Tumour Disease (DFTD), a transmissible cancer – the worst kind of diseases, and so far, they aren't doing so well. Since DFTD was discovered in 1996, ...

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Tasmanian devils to be released back on to mainland

Tasmanian devils to be released back on to mainland | Devil Facial Tumour Disease | Scoop.it
Devils, Leadbeater's possums and helmeted honeyeaters will gradually be released into Victorian 'halfway house' to test survival fitness
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Observations: Sequencing of Tasmanian Devil Genome Suggests New Attack on Contagious Cancer, Clues for Conservation

Observations: Sequencing of Tasmanian Devil Genome Suggests New Attack on Contagious Cancer, Clues for Conservation | Devil Facial Tumour Disease | Scoop.it

Tasmanian devils ( Sarcophilus harrisii ) have been besieged by a highly contagious cancer that has been pushing the species ever-closer to extinction .


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Aggressive Tasmanian Devils May Need to Chill Out to Survive

Aggressive Tasmanian Devils May Need to Chill Out to Survive | Devil Facial Tumour Disease | Scoop.it
Today in Solutions to Problems That Probably Don't Really Count As Solutions, scientists are proposing a new remedy to the bizarre, contagious facial tumors that are slowly but surely wiping out the world's Tasmanian devil population.

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Vaccine hope for Tasmanian devil tumor disease

Vaccine hope for Tasmanian devil tumor disease | Devil Facial Tumour Disease | Scoop.it
Researchers discover how transmissible facial cancer hides from the immune system.

 

Tasmanian devils are dying of a contagious cancer called devil facial tumor disease, which spreads between animals when they tussle over food. Now, a team of scientists has discovered how the disease infects new hosts by sneaking past the devil's immune system. The work could help in developing a vaccine that might prevent healthy devils from catching the cancer.

 

“It’s probably the most promising lead we’ve had for a vaccine since the initial characterization of the disease,” says immunogeneticist Hannah Siddle of the University of Cambridge, UK. Devil facial tumor disease emerged in 1996 and has slashed the Tasmanian devil population by 60%. If left unchecked, it could drive the species to extinction in 20–30 years.

 

Researchers had assumed that the disease spread easily between animals because of the devil's low genetic diversity, particularly in the genes of the major histocompatibility complex (MHC), which produce proteins that sit on the surface of cells and help the immune system to detect threats such as viruses or tumors. Once the disease emerged in one devil, presumably dodging its immune system by producing these proteins, it was thought that it would be able to fool the immune defences of the whole population.

 

But rather than producing the same MHC molecules found across all devils, Siddle and her colleagues found that the cancerous cells do not produce MHC molecules at all. “That was a big surprise,” she says. More surprising still was that the MHC genes in tumor cells had not been disabled by mutations. Instead, the genes responsible for the production of three proteins — β2-microglobulin, TAP1 and TAP2 — had been largely switched off. These proteins are necessary for transporting MHC to a cell’s membrane. Siddle even managed to reverse this problem using interferon-γ — a molecule that is known to encourage the production of MHC proteins. “The fact that it worked was wonderful and made perfect sense,” says Jim Kaufman, who was lead investigator on the study.

 

It is unclear if devil facial tumor disease will also evolve to be less aggressive with time, but with the Tasmanian devil facing extinction, Kaufman is not waiting to find out. He and his team are now working with Australian colleagues to develop a vaccine. Their plan is to prime healthy devils by giving them cancerous cells that already bear MHC proteins. Their immune systems should then recognize either tiny amounts of MHC on the surface of a cancer cell, or other proteins released as the tumors grow. “We’d start enough of an immune response to tip the balance in favour of the devil,” says Kaufman. “We’ve got some way to go, but we feel quite hopeful that we’ll come up with something.”

 

Although the priority is to save the Tasmanian devil from extinction, Kaufman also thinks that such research is important should a contagious cancer ever evolve to spread between humans. “Every once in a while, a new disease comes out of nowhere,” he says. “It’s useful to know what might hit people or other animals in the future.”

 


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Saving the Tassie Devils from Extinction - Veterinary Science Foundation - The University of Sydney

Saving the Tassie Devils from Extinction - Veterinary Science Foundation - The University of Sydney | Devil Facial Tumour Disease | Scoop.it
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Hope for threatened Tasmanian devils, and for humans!

Hope for threatened Tasmanian devils, and for humans! | Devil Facial Tumour Disease | Scoop.it
Greens claim funding decision will condemn Tasmanian Devils to extinction
ABC Online
The Australian Greens claim a federal government funding decision will condemn the Tasmanian devil to extinction.

Via Carlos Garcia Pando
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Carlos Garcia Pando's curator insight, March 27, 2013 5:44 AM

Sooner or later a human strain of contagious cancer will develop, and this work gives us insight into how these diseases emerge and evolve.

 

I wonder if some of the cancers we humans do  develop now are virus based or immunodeficiency based ase this one.

Apart from saving this iconic creature it's clear that it may also save us one day.

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Tasmanian Devils to Get Their Own Island : Discovery News

Tasmanian Devils to Get Their Own Island : Discovery News | Devil Facial Tumour Disease | Scoop.it
Greens claim funding decision will condemn Tasmanian Devils to extinction
ABC Online
The Australian Greens claim a federal government funding decision will condemn the Tasmanian devil to extinction.

Via Maria Nunzia @Varvera
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