Dental Implant and Bone Regeneration
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Dental Implant and Bone Regeneration
What’s happening in the world of implant dentistry by www.osteocom.net
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Engineering a Better Way to Rebuild Bone

Engineering a Better Way to Rebuild Bone | Dental Implant and Bone Regeneration | Scoop.it
Traumatic bone injuries are often so severe that the body can’t effectively repair the damage on its own. To aid the recovery, clinicians inject patients with proteins called growth factors. The treatment is costly, requiring large amounts of growth factors. The growth factors also disperse, creating unwanted bone formation. A new developing technology could provide more efficient delivery of the bone regenerating growth factors.
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The research team developed a method of fabricating pure heparin microparticles from a modified heparin methacrylamide species that can be thermally cross-linked to growth factors. The technology avoids the bulky materials currently used to deliver growth factors.

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Bone tissue engineering: Attaching proteins for better regeneration | CHEMISTRY NEWS

Researchers in Japan demonstrate a new protein binding approach for effectively promoting bone regeneration.

 

press release: http://chemnews.hoahocngaynay.com/article/4256

 

see abstract http://www.sciencedirect.com/science/article/pii/S0142961212005790

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An Activin A/BMP2 Chimera Displays Bone Healing Properties Superior to Those of BMP2

An Activin A/BMP2 Chimera Displays Bone Healing Properties Superior to Those of BMP2 | Dental Implant and Bone Regeneration | Scoop.it

Recombinant Bone Morphogenetic Protein 2 (rhBMP2) has been used clinically to treat bone fractures in human patients. However, the high doses of rhBMP2 required for a therapeutic response can cause undesirable side effects. Here, we demonstrate that a novel Activin A/BMP2 (AB2) chimera, AB204, promotes osteogenesis and bone healing much more potently and effectively than rhBMP2.

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