Mycoplasma is a common cell culture contaminant that can be hard to detect, and harder to treat. Most cell banks recommend that you discard a Mycoplasma-contaminated culture rather than treat it, but you may be handling something very precious where that is just not possible. So if you must treat, what is the best way to proceed?
This research article from the Leibniz Institute DSMZ (German Collection of Microorganisms and Cell Cultures) looks at how well Mycoplasma treatment works in practice, focusing on Plasmocin, a relatively new agent. The article also includes PCR primers for detecting many of the different Mycoplama species found in culture.
For an excellent review of Mycoplasma contamination by the same authors, see:
Via Amanda Capes-Davis