Alzheimer's Disease
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Landmark Alzheimer's Study Pinpoints Protein That Protects Aging Brain

Landmark Alzheimer's Study Pinpoints Protein That Protects Aging Brain | Alzheimer's Disease | Scoop.it
The conundrum has stumped doctors for years. Why do neurodegenerative diseases such as Alzheimer's affect only the elderly? Why do some people live to be over 100 with normal brain functioning while others develop dementia decades earlier?

Now, a ...
Pacific Cove's insight:

"If we could activate this stress-resistance gene network with drugs, it might be possible to intervene in the disease quite early," he added in a release. "Since Alzheimer's strikes late in life, delaying the onset of disease by just a few years could have a very substantial impact." #Alzheimers #Dementia

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Sandy Spencer's curator insight, April 4, 2014 8:48 AM

A few questions we all ponder. 

Alzheimer's Disease
Alzheimer's Disease Awareness - Dementia - Lewy Bodies - Caregiving  
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Diabetes Sugars and Alzheimer’s Brain Plaques Potentially Linked

Diabetes Sugars and Alzheimer’s Brain Plaques Potentially Linked | Alzheimer's Disease | Scoop.it
Diabetes and Alzheimer’s could have a cause-and-effect connection, according to a study published this week.
Pacific Cove's insight:

“Our results suggest that diabetes, or other conditions that make it hard to control blood sugar levels, can have harmful effects on brain function and exacerbate neurological conditions such as Alzheimer’s disease, said Shannon Macauley, a postdoctoral researcher at the school and the lead author.  #Alzheimer's #Dementia #Memory #Caregivers #Caregiving 

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Running evades dementia

Running evades dementia | Alzheimer's Disease | Scoop.it
Those attempting to guard against dementia should put down the crossword and go for a jog, British researchers have advised. - New Zealand Herald

Via Peter Mellow
Pacific Cove's insight:

For years, people have assumed that puzzles kept the brain active. But Professor Clive Ballard, professor of age-related disease at King's College London, said those who wanted the best chance of staving off dementia should opt for a run or a brisk walk.  #Alzheimer  #Memory #Dementia #Caregivers #Caregiving 

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The Reason Brain Diseases Have Quadrupled in 21 Years - PsyBlog

The Reason Brain Diseases Have Quadrupled in 21 Years - PsyBlog | Alzheimer's Disease | Scoop.it
Given the power of modern medicine, why have brain diseases increased by four times?
Pacific Cove's insight:

#Alzheimer's - Researchers have compared figures for neurological disease from 1989 with those from 2010 across 21 Western countries.  They found that dementia is starting, on average, a decade earlier in 2010 than it was in 1989.   #Dementia #Memory #Caregivers #Caregiving 

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Why Obese People May Be At High Risk For Memory Loss

Why Obese People May Be At High Risk For Memory Loss | Alzheimer's Disease | Scoop.it
Obesity, or more specifically the insulin resistance that is common to an overweight condition, is strongly associated with memory loss.
Pacific Cove's insight:

"Over the course of [Alzheimer’s disease], there is a progressive decrease in the amount of blood sugar used in certain brain regions. Those regions end up using less and less,” Willette said. “If you don't have as much fuel, you're not going to be as adept at remembering something or doing something.” #Alzheimer's #Dementia #Memory #Caregivers #Caregiving  

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As You Age Senior Home Care Services's curator insight, July 31, 2:08 PM

"Over the course of [Alzheimer’s disease], there is a progressive decrease in the amount of blood sugar used in certain brain regions. Those regions end up using less and less,” Willette said. “If you don't have as much fuel, you're not going to be as adept at remembering something or doing something.

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A Great Resource for Caregivers: The Alzheimer's Reading Room

A Great Resource for Caregivers: The Alzheimer's Reading Room | Alzheimer's Disease | Scoop.it
If you have a loved one with dementia, my first suggestion would be to find the very best doctors possible. My second piece of advice would be to go to the Alzheimer's Reading Room. It's a free blog that focuses on Alzheimer's disease and the art of Alzheimer's caregiving.
Pacific Cove's insight:

#Alzheimer's - @BobDeMarco - The site was established by Bob DeMarco, a former Wall Street professional from Delray Beach, Florida, who was the full-time caregiver to his mother, Dotty, for eight years. He started the site to keep track of the thousands of articles and numerous books he was reading about Alzheimer's disease to help him understand how to care for his mother.   #Dementia #Memory #Caregivers #Caregiving #BobDeMarco #AlzheimersReadingRoom

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Coping With Caregiver Grief and Alzheimer's Disease

Coping With Caregiver Grief and Alzheimer's Disease | Alzheimer's Disease | Scoop.it
Grief and loss often accompany the journeys of caregivers, sometimes for years in the case of Alzheimer's or related dementia. Family caregivers experience losses not only of the person they love, but losses of their own familiar roles and dreams for the future.
Pacific Cove's insight:

Profound personality changes can occur in the person with Alzheimer's and dementia, causing caregivers to feel like the person they are caring for is a stranger occupying a familiar body. Spouses who become caregivers may become cryptowidows, married in name but not in fact, and grieve the loss of intimacy, companionship, and sexuality.  #Alzheimer's #Dementia #Memory #Caregivers #Caregiving 

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Studies: Better Sleep May be Important for Alzheimer's Risk

Studies: Better Sleep May be Important for Alzheimer's Risk | Alzheimer's Disease | Scoop.it
To sleep, perchance to... ward off Alzheimer's? New research suggests poor sleep may increase people's risk of Alzheimer's disease, by spurring a brain-clogging gunk that in turn further interrupts shut-eye.
Pacific Cove's insight:

The new research suggests that sleep problems actually interact with some of the disease processes involved in Alzheimer's, and that those toxic proteins in turn affect the deep sleep that's so important for memory formation.  #Alzheimer's #Dementia #Memory #Sleep #Caregivers #Caregiving 

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As You Age Senior Home Care Services's curator insight, August 3, 1:23 PM

The new research suggests that sleep problems actually interact with some of the disease processes involved in Alzheimer's, and that those toxic proteins in turn affect the deep sleep that's so important for memory formation.  #Alzheimer's #Dementia #Memory #Sleep #Caregivers #Caregiving 

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Blood Protein May Indicate Risk of Alzheimer's Disease

Blood Protein May Indicate Risk of Alzheimer's Disease | Alzheimer's Disease | Scoop.it
Scientists have identified a single blood protein that may indicate the development of Mild Cognitive Impairment (MCI) years before symptoms appear, a disorder that has been associated with an increased risk of Alzheimer's disease or other dementias.
Pacific Cove's insight:

For the first time, they found that the blood level of a protein called MAPKAPK5 was, on average, lower in individuals whose cognitive ability declined over a ten year period.  #Alzheimer's #Dementia #Memory #Caregivers #Caregiving


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Click here to support Help me spread the word on dementia by Adam Sibley

Click here to support Help me spread the word on dementia by Adam Sibley | Alzheimer's Disease | Scoop.it

Dementia:    I spent four years caring for my mum when she developed dementia and I promised her that I would write a book about our experiences to help others going through the same thing. This book is about my journey with my mum, what we learnt, what we experienced, our ups & downs and how it m...

Pacific Cove's insight:

@Adam_Sibley - "Adam has succeeded in putting his finger on so many of the emotions and thoughts that carers encounter during dark days with a loved one and his positivity and determination will give the reader much needed encouragement and support." - Philip Lee  #Dementia #Alzheimer's #Memory #Caregivers #Caregiving  

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Music used to spark memories among dementia patients

Music used to spark memories among dementia patients | Alzheimer's Disease | Scoop.it
Barbara Rashid sat in an armchair in a quiet nook of the Columbus nursing home, staring off into the distance. She didn’t stir or react, even when friends greeted her as they left the dining hall at Forest Hills on the North Side. But as soon as the activities director slipped headphones on her, Rashid, 75, started tapping her hands and feet to the sweet sounds coming from the iPod. Within seconds, she was bobbing her head to the music.
Pacific Cove's insight:

April McDaniel, the activity director at Forest Hills, has seen music calm an upset resident and return a smile to the face of someone whose personality has been stolen by dementia.  #Alzheimer's #Dementia #Memory #Music #Caregivers #Caregiving

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As You Age Senior Home Care Services's curator insight, August 3, 1:26 PM

April McDaniel, the activity director at Forest Hills, has seen music calm an upset resident and return a smile to the face of someone whose personality has been stolen by dementia.  #Alzheimer's #Dementia #Memory #Music #Caregivers #Caregiving

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Nasal Spray Effective Treatment For Memory Loss and Alzheimer's, Study Finds - PsyBlog

Nasal Spray Effective Treatment For Memory Loss and Alzheimer's, Study Finds - PsyBlog | Alzheimer's Disease | Scoop.it
Memory loss and Alzheimer's treated with a nasal spray over 21 days.
Pacific Cove's insight:

Professor Suzanne Craft, who led the study, said:  “The study provides preliminary evidence that insulin detemir can provide effective treatment for people diagnosed with mild cognitive impairment and Alzheimer’s-related dementia similar to our previous work with regular insulin.  #Alzheimer's #Dementia #Caregivers #Caregiving #Memory

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Alzheimer’s Expert Jams with Aerosmith

Alzheimer’s Expert Jams with Aerosmith | Alzheimer's Disease | Scoop.it
One of the world’s leading Alzheimer’s researchers doubles as a guest organist for Aerosmith.
Pacific Cove's insight:

After he switched his work to focus on Alzheimer’s, the disease hit close to home when his grandmother began coming down with tell-tale symptoms.  #Alzheimer's #Dementia #Caregiving #Caregiviers 

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Scientists Look into Why Most Alzheimer's Patients are Women

Scientists Look into Why Most Alzheimer's Patients are Women | Alzheimer's Disease | Scoop.it
Nearly two-thirds of Americans with Alzheimer's disease are women, and now some scientists are questioning the long-held assumption that it's just because they tend to live longer than men.
Pacific Cove's insight:

A recent Alzheimer's Association report estimates that at age 65, women have about a 1 in 6 chance of developing Alzheimer's during the rest of their lives, compared with a 1 in 11 chance for men.  #Alzheimer's #Dementia #Caregivers #Caregiving

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Study: Women With Mild Memory Problem Worsen Faster Than Men

Study: Women With Mild Memory Problem Worsen Faster Than Men | Alzheimer's Disease | Scoop.it
Older women with mild memory impairment worsened about twice as fast as men, researchers reported Tuesday, part of an effort to unravel why women are especially hard-hit by Alzheimer's.
Pacific Cove's insight:

Nearly two-thirds of Americans with Alzheimer's are women.

At age 65, seemingly healthy women have about a 1 in 6 chance of developing Alzheimer's during the rest of their lives...  #Alzheimers #Dementia #Memory #Caregivers #Caregiving 

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Compassionate new spoons and plates make it easier for people with Alzheimer's to eat

Compassionate new spoons and plates make it easier for people with Alzheimer's to eat | Alzheimer's Disease | Scoop.it
Eatwell is an 8-piece dining set that fosters mealtime independence for suffers of dementia.
Pacific Cove's insight:

#Alzheimer's - The result of all these intentional elements working together is a dining set that has been found to allow users with dementia to consume 24% more food and 84% more liquid, according to Boston University research.  #Dementia #Memory #Caregivers #Caregiving 

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Pacific Cove's curator insight, August 27, 6:25 PM

#Alzheimer's - The result of all these intentional elements working together is a dining set that has been found to allow users with dementia to consume 24% more food and 84% more liquid, according to Boston University research.  #Dementia #Memory #Caregivers #Caregiving 

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Program uses music to combat Alzheimer's - 9NEWS.com

Program uses music to combat Alzheimer's - 9NEWS.com | Alzheimer's Disease | Scoop.it
A pilot program at a Denver retirement community is using music to get through to those suffering from Alzheimer's.
Pacific Cove's insight:

"He found that there was a statistically significant improvement, in the cognition, which is kind of a big deal because Alzheimer's disease, and dementia, are conditions that don't have a cure, don't have any proven treatments right now," Steward said.  #Alzheimer's #Dementia #Memory #Caregivers #Caregiving #Music

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iSeniorSolutions.com's curator insight, August 1, 7:51 PM

"He found that there was a statistically significant improvement, in the cognition, which is kind of a big deal because Alzheimer's disease, and dementia, are conditions that don't have a cure, don't have any proven treatments right now," Steward said.  #Alzheimer's #Dementia #Memory #Caregivers #Caregiving #Music

As You Age Senior Home Care Services's curator insight, August 14, 1:52 PM

music is moving through the retirement communities and many more places to relax Alzheimer Patients

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Antibody Drugs for Alzheimer's Show Glimmers of Promise

Antibody Drugs for Alzheimer's Show Glimmers of Promise | Alzheimer's Disease | Scoop.it
After a string of failed trials, drugs that target protein build-up in the brain appear to slow disease progress
Pacific Cove's insight:

Lilly, of Indianapolis, Indiana, says that in a trial with 440 participants, solanezumab seemed to slow the cognitive decline of people with mild Alzheimer’s by about 30%.  #Alzheimer's #Dementia #Memory #Caregivers #Caregiving 

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Scientists warn that new drugs will require earlier diagnosis of Alzheimer’s

Scientists warn that new drugs will require earlier diagnosis of Alzheimer’s | Alzheimer's Disease | Scoop.it
Announcement about success of solanezumab leads to calls for improved testing to identify those who would benefit from slowing of mental decline
Pacific Cove's insight:

The trouble is that, at present, diagnosis of Alzheimer’s is still an imperfect science. “About 25% of diagnoses by doctors of early-stage Alzheimer’s are incorrect,” said Eric Karran, director of research for Alzheimer’s Research UK.  #Alzheimer's #Dementia #Memory #Caregivers #Caregiving 

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New Alzheimer's studies show women with memory problems decline twice as fast as men

New Alzheimer's studies show women with memory problems decline twice as fast as men | Alzheimer's Disease | Scoop.it
Elderly women are more likely than elderly men to develop Alzheimer's disease, even when they are exposed to some of the same risk factors, two new studies find.
Pacific Cove's insight:

Studies such as these may help researchers understand why nearly two-thirds of American seniors with Alzheimer's disease are women, said Maria Carrillo, chief scientific officer of the Alzheimer's Association.  #Alzheimer's #Dementia #Memory #Caregivers #Caregiving 

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Brain Changes Differ by Race With Alzheimer's Disease: Study

Brain Changes Differ by Race With Alzheimer's Disease: Study | Alzheimer's Disease | Scoop.it
Blacks more likely to have additional dementia-related changes in their brains, researchers say
Pacific Cove's insight:

Autopsies of black and white Alzheimer's patients revealed that blacks were more likely than whites to experience a mix of dementia-related changes, as opposed to the damage usually associated with "pure" Alzheimer's dementia, according to the study.#Alzheimer's #Dementia #Memory #Caregivers #Caregiving 

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Alzheimer's Affects Black and White Brains Differently, Study Says

Alzheimer's Affects Black and White Brains Differently, Study Says | Alzheimer's Disease | Scoop.it

Alzheimer's Alzheimer’s disease causes deteriorating changes in the brain. But those changes may be different for people of different races, according to a new study released today.

Pacific Cove's insight:

“Our study has important clinical implications because it may suggest a need for different types of Alzheimer’s prevention and treatments in African Americans,” she said.  #Alzheimer's #Dementia #Seniors #SeniorCare #Caregiving #Caregivers 

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As You Age Senior Home Care Services's curator insight, August 3, 1:24 PM

“Our study has important clinical implications because it may suggest a need for different types of Alzheimer’s prevention and treatments in African Americans,” she said.  #Alzheimer's #Dementia #Seniors #SeniorCare #Caregiving #Caregivers 

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Dementia patients forced to rely on unpaid carers, poll says

Dementia patients forced to rely on unpaid carers, poll says | Alzheimer's Disease | Scoop.it
Survey by Alzheimer’s Society finds dementia patients require support of family and friends after being let down by health and social care system
Pacific Cove's insight:

Dementia has been described as a ticking timebomb with the number of people in the UK expected to increase from 850,000 currently to over one million by 2021 and two million by 2051.  #Alzheimers #Dementia #Memory #Caregivers #Caregiving 

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Can Technology Ease The Burden Of Caring For People With Dementia?

Can Technology Ease The Burden Of Caring For People With Dementia? | Alzheimer's Disease | Scoop.it
Things like activity trackers and sensors might make it easier to keep people with dementia safe and help caregivers. Researchers are going to test that idea in the real world.
Pacific Cove's insight:

This burden is going increase dramatically in the coming decade. By 2025, 7 million Americans will have Alzheimer's disease, according to one recent estimate. Millions more will suffer from other types of dementia.  #Alzheimer's #Dementia #Memory #Caregivers #Caregiving

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Forgetfulness and Errors Can Signal Alzheimer’s Decades Before Diagnosis

Forgetfulness and Errors Can Signal Alzheimer’s Decades Before Diagnosis | Alzheimer's Disease | Scoop.it
Mistakes on memory and thought tests may give an indication of the future onset of Alzheimer’s, up to 18 years before diagnosis, according to a new study.
Pacific Cove's insight:

Previous studies have shown that the brain is undergoing structural changes before Alzheimer’s has taken hold. Other studies have shown cognitive decline starts in early stages of the disease. But the new research indicates there could be a longer lead-up to diagnosis than has been indicated.  #Alzheimer's #Dementia #Caregiving #Caregivers 

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High Blood Pressure Linked to Reduced Alzheimer's Risk, Meds May be Reason

High Blood Pressure Linked to Reduced Alzheimer's Risk, Meds May be Reason | Alzheimer's Disease | Scoop.it
A new study suggests that people with a genetic predisposition to high blood pressure have a lower risk for Alzheimer's disease.
Pacific Cove's insight:

"It's likely that this protective effect is coming from antihypertensive drugs," said co-author John Kauwe, associate professor of biology at Brigham Young University. "These drugs are already FDA approved. We need to take a serious look at them for Alzheimer's prevention."  #Alzheimer's #Dementia #Caregivers #Caregiving 

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