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Latest news on complex systems in life sciences, engineering, education and government
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In the Pipeline:

In the Pipeline: | Complex Insight  - Understanding our world | Scoop.it

Derek Lowe's  blog is a regular must read for insight into what is happening in the pharma industry.  This post is a good overview of the current debate on how drugs (and other molecules) actually get into cells - Is it passive diffusion or active transport or a mix of the two? The truth is we still don't know exactly which process does what and a debate between scientists was recently re-ignited by a paper from Paul Dobson (now of the University of Sheffield) and his former colleagues at the University of Manchester... Learn More...

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TGen News - Largest Autism Study Ever Conducted Using DNA Array Technology

While autism was first identified more than 50 years ago, the disorder remains a medical mystery because the tools necessary to learn more about the genetics of autism simply did not exist. With the development of promising new technology and 6,000 genetic samples, the research "dream team" of the NAAR Autism Genome Project hopes to reveal genetic information about autism that was previously undetectable. Learn more...

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Pharma land

Pharma land | Complex Insight  - Understanding our world | Scoop.it

The Swiss chemical and pharmaceutical industry – accounts for over 4 % of Gross Domestic Product and is the second most important industry, behind the engineering industry for the swiss economy. Good overview of the companies pharma industry.

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Science-Based Medicine » Why haven’t we cured cancer yet?

Science-Based Medicine » Why haven’t we cured cancer yet? | Complex Insight  - Understanding our world | Scoop.it

Cancer is not a single disease. It’s hundreds of diseases. Each tumor can be many diseases that are constantly evolving, both in response to the environment in which the cancer cells grow and to treatments that are thrown at them.Understanding the complexity and interaction networks that govern why cells go into a cancering state is critical to understanding the diseases. This older article by David Gorski helps explain just why finding cures for cancer have been so elusive... Read more...

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Turing was right: Two proteins fit decades-old prediction

Turing was right: Two proteins fit decades-old prediction | Complex Insight  - Understanding our world | Scoop.it
Today, Alan Turing is best known as the father of modern computer science, but in 1952 he sketched out a biological model in which two chemicals — an activator and an inhibitor — could interact to form the basis for everything from the color...
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Connecting the digital and biological worlds

Connecting the digital and biological worlds | Complex Insight  - Understanding our world | Scoop.it
To a generation which grew up with computers, the field of synthetic biology - creating artificial life forms - is a story they can relate to, said American geneticist Craig Venter.
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Evolution finds shelter in small spaces. [Chem Biol. 2012] - PubMed - NCBI

One for the commute reading pile: When RNA is replicated in cell-free systems, a ubiquitous problem is the hijacking of the system by short parasitic RNA sequences. In this issue of Chemistry & Biology, Bansho et al. show that compartmentalization into water-in-oil droplets can ameliorate this problem, but only if the droplets are small. This result helps to both recapitulate abiogenesis and optimize synthetic biology.

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BioPortfolio - the Biotechnology, Pharmaceutical, Life-Science and Healthcare Portal

BioPortfolio - the Biotechnology, Pharmaceutical, Life-Science and Healthcare Portal | Complex Insight  - Understanding our world | Scoop.it
BioPortfolio.com - the life science and healthcare portal BioPortfolio brings our visitors continuously updated biotechnology, pharmaceutical and healthcare n...
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mBiosphere: Commentary: Black Queen Hypothesis sheds light on evolution of complexity

mBiosphere: Commentary: Black Queen Hypothesis sheds light on evolution of complexity | Complex Insight  - Understanding our world | Scoop.it

mBio is a great source for developments in biology. This week they have a good commentary on the Sachs and Hollowell Black Queen hypothesis which has implications for how we understand the evolution of bacterial genomes and for the development of new techniques for growing bacteria in the lab.  Learn More...

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Roche looks to personal future

Roche looks to personal future | Complex Insight  - Understanding our world | Scoop.it
Swiss pharmaceutical company Roche, with over SFr9.5 billion ($10.35 billion) in profits for 2011, is looking to secure its future and betting on personalised medicine in the process.
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Bio-Linux 6 ~ Bioinformatics made Simple

Bio-Linux 6 ~ Bioinformatics made Simple | Complex Insight  - Understanding our world | Scoop.it
Bio-Linux is an operating system set up for bioinformatics with a vast number of programs pre-installed. It can be obtained for free from the NERC Environmental Bioinformatics Centre. You can obtain a USB drive from NERC and boot from that ...

Via Dr Richard Badge
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Open-data project aims to ease the way for genomic research

Open-data project aims to ease the way for genomic research | Complex Insight  - Understanding our world | Scoop.it

This one is important to us as we start testing OLAPX and BIOLAP approaches for data analysis.  The Ewing Marion Kauffman Foundation, based in Kansas City, Missouri,  aims to “create the world’s largest pool of openly available, user-contributed data about health and genomics” in hopes of easing challenges with informed consent and data ownership that some biomedical researchers say are holding science back in the era of ‘big data’. Learn more...

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Darwinian chemistry: towards the synthesis of a ... [Mol Biosyst. 2009] - PubMed - NCBI

8 years back one of the papers that blew my mind was J.W.Szostak  et al's  paper on the total synthesis of cellular mechanisms of a simple cell. This paper by Loakes and Holliger gives a great update on the fascinating field of synthetic biology.

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Harvard University says it can't afford journal publishers' prices

Harvard University says it can't afford journal publishers' prices | Complex Insight  - Understanding our world | Scoop.it
University wants scientists to make their research open access and resign from publications that keep articles behind paywalls (Will others follow suit = important question MT @GozdeZorlu Harvard Uni says it can't afford journal publishers' prices...
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Researchers Turn Big Data Problems into Advanced Biology and Drug Discoveries | BioPortfolio.com

Researchers Turn Big Data Problems into Advanced Biology and Drug Discoveries | BioPortfolio.com | Complex Insight  - Understanding our world | Scoop.it
From BioPortfolio: SGI (NASDAQ:SGI), the trusted leader in technical computing, today announced that researchers in the compute-intensive field of biotechnology research are conti...
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