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Rescooped by Artem Kortelev from Multiple sclerosis New Drugs Review
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Biogen kills its LINGO-1 (anti-TWEAK) R&D in Lupus Nephritis

Biogen kills its LINGO-1 (anti-TWEAK) R&D in Lupus Nephritis | Coagulation | Scoop.it

Biogen has ended its ATLAS - Anti-Tweak in Lupus Nephritis Patients

 

 

Anti-LINGO-1 (BIIB033)

Multiple sclerosis (MS)

 

 

 

A 2009 Phase III failure of Rituxan plus mycophenolate mofetil and corticosteroids in patients with lupus nephritis did not meet its primary endpoint of significantly reducing disease activity at 52 weeks. (with Genentech)

 

 


Via Krishan Maggon
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Krishan Maggon 's curator insight, October 23, 2015 10:54 AM

 

A high-profile experimental treatment to repair the damaged myelin around nerves in people with multiple sclerosis (MS) has passed its first clinical testing milestone. The drug, a monoclonal antibody called BIIB033 (Biogen Idec), is safe and tolerable in people, according to the combined results of two phase 1 clinical trials that tested high doses inhealthy people and in people with MS.

Rescooped by Artem Kortelev from Pharma & Medical Devices
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One-quarter of deaths from heart disease, stroke avoidable, CDC says

One-quarter of deaths from heart disease, stroke avoidable, CDC says | Coagulation | Scoop.it
At least 200,000 deaths due to heart disease and stroke can be prevented each year by quitting smoking , controlling blood pressure and cholesterol, and taking aspirin when recommended by a physician, according to the U.S.

Via Richard Meyer
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