When we talk about change, in the brain, we're talking about creating new neural links, replacing the "old trick" pathway with the new "trick." Keep learning.
I love this example of the London cabbie - they can't be stumped. And science shows "the part of the brain that holds spatial representation capacity -- is measurably larger than that of a bus driver. By driving the same route every day, the bus drivers don't need to exercise this part of the brain as much. The cabbies, on the other hand, rely on it constantly for navigation."