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The Significance of the 2013 Nobel Prize in Chemistry and the Challenges Ahead - PLoS Blogs (blog)

The Significance of the 2013 Nobel Prize in Chemistry and the Challenges Ahead - PLoS Blogs (blog) | Chemistry | Scoop.it
PLoS Blogs (blog) The Significance of the 2013 Nobel Prize in Chemistry and the Challenges Ahead PLoS Blogs (blog) Following the announcement of the 2013 Nobel Prize in Chemistry, PLOS Computational Biology Editor-in-Chief Ruth Nussinov discusses...
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Countdown To The 2013 Chemistry Nobel Prize Events | Chemical ...

Countdown To The 2013 Chemistry Nobel Prize Events | Chemical ... | Chemistry | Scoop.it
Watch this archived web broadcast for Chemistry Nobel Prize-related discussion and predictions from C&EN reporters and special guests. Credit: C&EN/Google Hangouts. As announcement of the Nobel Prizes draws near ...
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Students make magic with chemistry - Quad City Times

Students make magic with chemistry - Quad City Times | Chemistry | Scoop.it
Students make magic with chemistry
Quad City Times
To mark National Chemistry Week, the Augustana College student chapter of the American Chemical Society threw its semi-annual open house Saturday afternoon for the 24th year.
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2013 Nobel Prize In Chemistry Winners - Business Insider

2013 Nobel Prize In Chemistry Winners - Business Insider | Chemistry | Scoop.it
The 2013 Nobel Prize in Chemistry has been awarded to Martin Karplus, Michael Levitt and Arieh Warshel for theoretical chemistry.
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Basic Energy Quiz

Basic Energy Quiz | Chemistry | Scoop.it
In keeping with the National Chemistry Week energy theme, here's a ten question quiz to get you thinking about what energy is and the different forms it (Basic Energy Quiz: In keeping with the National Chemistry Week energy theme, here's a ten...
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Nobel Prize in chemistry awarded for work that led to complex computing - CNN

Nobel Prize in chemistry awarded for work that led to complex computing - CNN | Chemistry | Scoop.it
New York Times (blog)
Nobel Prize in chemistry awarded for work that led to complex computing
CNN
(CNN) -- Chemists used to use balls and sticks to make models to help them understand how molecules worked.
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Predictions for the 2013 Nobel Prize in Chemistry | ChemBark

Predictions for the 2013 Nobel Prize in Chemistry | ChemBark | Chemistry | Scoop.it
ChemBark Medallion Here it comes…the world of chemistry's most exciting hour of fantastic prizes. Early this Wednesday morning, the winner(s) of the 2013 Nobel Prize in Chemistry will be announced. After a modest run of ...
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Lingzhiols, Unprecedented Rotary Door-Shaped Meroterpenoids as Potent and Selective Inhibitors of p-Smad3 from Ganoderma lucidum

Lingzhiols, Unprecedented Rotary Door-Shaped Meroterpenoids as Potent and Selective Inhibitors of p-Smad3 from Ganoderma lucidum | Chemistry | Scoop.it

(+)-Lingzhiol and (−)-lingzhiol, a pair of rotary door-shaped meroterpenoidal enantiomers, were isolated from Ganoderma lucidum. Their structures were identified by spectroscopic methods and X-ray diffraction crystallography. Lingzhiol bears an unusual 5/5/6/6 ring system characteristic of sharing a C-3′–C-7′ axis. Biological evaluation showed that (+)-lingzhiol or (−)-lingzhiol could selectively inhibit the phosphorylation of Smad3 in TGF-β1-induced rat renal proximal tubular cells and activate Nrf2/Keap1 in mesangial cells under diabetic conditions.

 

Yong-Ming Yan †‡, Jun Ai §, Li−Li Zhou §, Arthur C.K. Chung , Rong Li , Jing Nie §, Ping Fang †,Xin-Long Wang †, Jie Luo †, Qun Hu †, Fan-Fan Hou*§, and Yong-Xian Cheng

 

Org. Lett., Article ASAP

DOI: 10.1021/ol4026364


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Referencing: The reuse factor

Referencing: The reuse factor | Chemistry | Scoop.it
The reference is not dead — it is exploding to encompass the full spectrum of research outputs from lines of code to video frames, explains Mark Hahnel.

 

Data are the bedrock of a paper and come in myriad forms; for instance, videos for research on cell motility or biomechanics, or code for climate or epidemiology models. Scholars are increasingly sharing these sorts of raw data through repositories such as the Dryad Digital Repository and GenBank, which allow for the citation of data sets, videos, genetic sequences and other such files that publishers often struggle to accommodate.


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Molecularly imprinted polymers for the isolation of bioactive naphthoquinones from plant extracts

Molecularly imprinted polymers for the isolation of bioactive naphthoquinones from plant extracts | Chemistry | Scoop.it

• Molecularly Imprinted Polymers for isolation of shikonin from plant extracts were prepared.• Strong association of shikonin with both acidic and basic monomers was found by UV–vis titrations.• Polymerisation inhibition in the presence of basic monomers was investigated by solid state NMR.• Recoveries up to 72% from commercial shikonin samples were achieved using DEAEMA based imprints.

 

Stella K. Tsermentselia, Panagiotis Manesiotisb, , , Andreana N. Assimopouloua, , , Vassilios P. Papageorgiou

Journal of Chromatography A

Volume 1315, 8 November 2013, Pages 15–20


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NatProdChem's curator insight, October 17, 2013 11:04 PM

Molecular Imprinting as a stereoselective and ecological purification procedure

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Michael Levitt wins Nobel Prize in Chemistry - Stanford News

Michael Levitt wins Nobel Prize in Chemistry - Stanford News | Chemistry | Scoop.it
Levitt shares the prize with Martin Karplus of Université de Strasbourg, France, and Harvard University, and Arieh Warshe of the University of Southern California, "for the development of multiscale models for complex ...
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"Transition from Inorganic to Organic Life was Based on Information ...

"Transition from Inorganic to Organic Life was Based on Information ... | Chemistry | Scoop.it
In December of 2012, a radical new approach to the question of life's origin was proposed by two Arizona State University scientists that attempts to dramatically redefine the problem. The researchers – Paul Davies, an ASU ...
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The human being as unwitting research object for industrial chemistry

The human being as unwitting research object for industrial chemistry | Chemistry | Scoop.it
There are a few excellent movies that are well-worth viewing if you are interested in the connection between environmental pollution and human health. I've written a blog about Unacceptable Levels highlighting its excellent ...
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Nobel Prize In Chemistry Awarded To Taft Middle School Teacher Mr. Ambler

Nobel Prize In Chemistry Awarded To Taft Middle School Teacher Mr. Ambler | Chemistry | Scoop.it
STOCKHOLM—In recognition of his contributions to the field of making sixth-grade chemistry fun, Taft Middle School teacher Peter Ambler was awarded the Nobel Prize in Chemistry on Monday.
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The Significance of the 2013 Nobel Prize in Chemistry and the Challenges Ahead - PLoS Blogs (blog)

The Significance of the 2013 Nobel Prize in Chemistry and the Challenges Ahead - PLoS Blogs (blog) | Chemistry | Scoop.it
PLoS Blogs (blog) The Significance of the 2013 Nobel Prize in Chemistry and the Challenges Ahead PLoS Blogs (blog) Following the announcement of the 2013 Nobel Prize in Chemistry, PLOS Computational Biology Editor-in-Chief Ruth Nussinov discusses...
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2013 Nobel Prize In Chemistry - Chemical & Engineering News

2013 Nobel Prize In Chemistry - Chemical & Engineering News | Chemistry | Scoop.it
Karplus (from top), Levitt, and Warshel are shown at their homes. Warshel, with his wife, Tami, is on the phone with Israeli President Shimon Peres. Theoretical chemistry doesn't always get the respect it deserves.
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Meroterpenoids with Diverse Ring Systems from the Sponge-Associated Fungus Alternaria sp. JJY-32

Meroterpenoids with Diverse Ring Systems from the Sponge-Associated Fungus Alternaria sp. JJY-32 | Chemistry | Scoop.it

Fifteen meroterpenoids (1–15) with diverse ring systems including an unprecedented oxaspiro[5.5]nonane-fused cyclohexenone (1), hydrogenated benzofurans (2–5), hydrogenated chromans (6, 7), hydrogenated cyclopenta[b]chromans (8–11), and four monocyclic structures (12–15) were isolated from the sponge-associated fungus Alternariasp. JJY-32. The structures were elucidated by detailed spectroscopic analysis, including 2D NMR and electronic circular dichroism (ECD) calculations, and assisted by chemical derivatizations. On the basis of supplementation experiments with specific enzyme inhibitors and putative precursors, a shikimate–isoprenoid hybrid biosynthetic pathway is proposed. The NF-κB inhibitory activities of 1–15 were tested, and all of them, except 6 and7 (IC50 > 100 μM), showed activities with IC50 values ranging from 39 to 85 μM in RAW264.7 cells.

 

Guojian Zhang †, Guangwei Wu †, Tianjiao Zhu †,Tibor Kurtán ‡, Attila Mándi ‡, Jieying Jiao †, Jing Li †, Xin Qi †, Qianqun Gu †, and Dehai Li

 

J. Nat. Prod., Article ASAP

DOI: 10.1021/np4005757


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Akaeolide, a Carbocyclic Polyketide from Marine-Derived Streptomyces

Akaeolide, a Carbocyclic Polyketide from Marine-Derived Streptomyces | Chemistry | Scoop.it

Akaeolide, a novel polycyclic polyketide, was isolated from the culture extract of a marine-derived actinomycete belonging to the genus Streptomyces. The planar structure of the new compound was elucidated by spectroscopic analysis including NMR and MS, and the absolute configuration was determined by X-ray crystallographic analysis of its chlorinated derivative. Akaeolide possesses a 15-membered carbocyclic framework, apparently derived from the malonate pathway, with a tetrahydrofuran ring and a β-keto-δ-lactone unit.

 

Yasuhiro Igarashi *†, Tao Zhou †, Seizo Sato ‡,Takashi Matsumoto §, Linkai Yu †, and Naoya Oku

 

Org. Lett., Article ASAP

DOI: 10.1021/ol402661r

 

 


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Q&A: A man of many dimensions : Nature : Nature Publishing Group

Q&A: A man of many dimensions : Nature : Nature Publishing Group | Chemistry | Scoop.it
Richard R. Ernst pioneered one- and two-dimensional nuclear magnetic resonance (NMR), and talks to Stephanie Harris about why dimensions are important in life as well as in science.

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A Listener’s Guide to My 1st Chemistry Set with Boldy JamesNah Right

A Listener’s Guide to My 1st Chemistry Set with Boldy JamesNah Right | Chemistry | Scoop.it
A track-by-track guide to the new project from @BoldyJames & @Alchemist: 'My 1st Chemistry Set' http://t.co/cGO2WxCHzd
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A Look at the Chemistry, Dangers of Dry Ice - ABC News

A Look at the Chemistry, Dangers of Dry Ice - ABC News | Chemistry | Scoop.it
A Look at the Chemistry, Dangers of Dry Ice
ABC News
A baggage handler arrested after dry ice bombs exploded at the Los Angeles International Airport had planted the devices as a prank, authorities said Wednesday.
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