Cancer Biomarkers
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Cancer Biomarkers
Full length peer reviewed articles on cancer biomarkers
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Basal-Like Breast Cancer Defined by Five Biomarkers Has Superior Prognostic Value than Triple-Negative Phenotype

The expanded surrogate immunopanel of estrogen receptor, progesterone receptor, human HER-2, EGFR, and cytokeratin 5/6 provides a more specific definition of basal-like breast cancer that better predicts breast cancer survival.

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Three Biomarkers Identified from Serum Proteomic Analysis for the Detection of Early Stage Ovarian Cancer

Early detection remains the most promising approach to improve long-term survival of patients with ovarian cancer. Three biomarkers were identified as follows: (a) apolipoprotein A1 (down-regulated in cancer); (b) a truncated form of transthyretin (down-regulated); and (c) a cleavage fragment of inter-α-trypsin inhibitor heavy chain H4 (up-regulated).

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Laboratory Investigation - Plasma microRNAs as potential biomarkers for non-small-cell lung cancer

Laboratory Investigation - Plasma microRNAs as potential biomarkers for non-small-cell lung cancer | Cancer Biomarkers | Scoop.it
Laboratory Investigation is the official journal of the United States and Canadian Academy of Pathology. Laboratory Investigation is available as both in print and online journal and is dedicated to the publication of original research that significantly advances the understanding of human and experimental disease including basic biology papers with a relevance to experimental or clinical aspects of disease. The journal also publishes papers detailing relevant advances in technical methodology.
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Prognostic Relevance of Integrated Genetic Profiling in Acute Myeloid Leukemia — NEJM

Prognostic Relevance of Integrated Genetic Profiling in Acute Myeloid Leukemia — NEJM | Cancer Biomarkers | Scoop.it
Original Article from The New England Journal of Medicine — Prognostic Relevance of Integrated Genetic Profiling in Acute Myeloid Leukemia
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Prognostic Impact of Hyaluronan and Its Regulators in Pancreatic Ductal Adenocarcinoma

Prognostic Impact of Hyaluronan and Its Regulators in Pancreatic Ductal Adenocarcinoma | Cancer Biomarkers | Scoop.it
PLOS ONE: an inclusive, peer-reviewed, open-access resource from the PUBLIC LIBRARY OF SCIENCE. Reports of well-performed scientific studies from all disciplines freely available to the whole world.
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Soluble Mesothelin-Related Peptide Level Elevation in Mesothelioma Serum and Pleural Effusions

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Cyclin D1b variant influences prostate cancer growth through aberrant androgen receptor regulation

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Adenosine-to-Inosine RNA Editing Mediated by ADARs in Esophageal Squamous Cell Carcinoma

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MicroRNA miR-21 overexpression in human breast cancer is associated with advanced clinical stage, lymph node metastasis and patient poor prognosis

A monthly journal publishing high-quality, peer-reviewed research on all topics related to RNA and its metabolism in all organisms
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Clinical Usefulness of Plasma Chromogranin A in Pancreatic Neuroendocrine Neoplasm

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The HE4 (WFDC2) Protein Is a Biomarker for Ovarian Carcinoma

The WFDC2 (HE4) gene is amplified in ovarian carcinomas, whereas its expression in normal tissues, including ovary, is low. Although the function of the HE4 protein is unknown,it is a member of a family of stable 4-disulfide core proteins that are secreted at high levels. We therefore performed experiments to explore whether quantitation of HE4 protein levels in serum can be used as a biomarker for ovarian carcinoma.

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Biomarker Research | Full text | Biomarkers for hepatocellular carcinoma: progression in early diagnosis, prognosis, and personalized therapy

Hepatocellular carcinoma (HCC) is one of the most common malignant tumors in the world. Currently, surgical resection, liver transplantation, and local ablation are considered curative therapeutic practices for HCC. The diagnosis of HCC without pathologic confirmation is achieved by analyzing serum alpha-fetoprotein (AFP) levels combined with imaging techniques, including ultrasonography, magnetic resonance imaging, and computerized tomography. Although progress has been made in the diagnosis and management of HCC, its prognosis remains dismal. Various new technologies have identified numerous novel biomarkers with potential diagnostic as well as prognostic value, including Dickkopf-1 and Golgi protein 73. These biomarkers not only help in the early diagnosis and prediction of prognosis, but also assist in identifying potential targets for therapeutic interventions. In this article, we provide an up-to-date review of the biomarkers that are used for early diagnosis, prognosis prediction, and personalized treatment of HCC.
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Aberrant methylation of p16INK4a is an early event in lung cancer and a potential biomarker for early diagnosis

These studies show for the first time that an epigenetic alteration, aberrant methylation of the p16 gene, can be an early event in lung cancer and may constitute a new biomarker for early detection and monitoring of prevention trials.

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Fibulin-3 as a Blood and Effusion Biomarker for Pleural Mesothelioma — NEJM

Fibulin-3 as a Blood and Effusion Biomarker for Pleural Mesothelioma — NEJM | Cancer Biomarkers | Scoop.it
Original Article from The New England Journal of Medicine — Fibulin-3 as a Blood and Effusion Biomarker for Pleural Mesothelioma
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MYC-driven accumulation of 2-hydroxyglutarate is associated with breast cancer prognosis

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Identification of Isocitrate Dehydrogenase 1 as a Potential Diagnostic and Prognostic Biomarker for Non-small Cell Lung Cancer by Proteomic Analysis

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Tumor Suppressive Function of mir-205 in Breast Cancer Is Linked to HMGB3 Regulation

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Circulating Proteolytic Products of Carboxypeptidase N for Early Detection of Breast Cancer

Circulating Proteolytic Products of Carboxypeptidase N for Early Detection of Breast Cancer | Cancer Biomarkers | Scoop.it
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