Cancer - Advances, Knowledge, Integrative & Holistic Treatments
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Chronic Inflammation Resulting from Typical Lifestyle Choices Promotes Cancer

Chronic Inflammation Resulting from Typical Lifestyle Choices Promotes Cancer | Cancer - Advances, Knowledge, Integrative & Holistic Treatments | Scoop.it
Chronic inflammation has started to become a buzzword in the health world as research builds indicating that it may be the cause of many serious illnesses, from heart disease to cancer.
Graham Player Ph.D.'s insight:

There is direct connection between chronic inflammation and the development of cancer, as well as many other disease states. Many factors can contribute to chronic inflammation including stress, toxins, genetic predisposition, lack of exercise and diet.

Many doctors today recommend people take daily anti-inflammatory medicine, such as aspirin, to reduce their chances of developing chronic long-term inflammation. While this may be the case, research indicates this practice may be causing more harm than good for some people.

One byproduct of inflammation is an increase in C-reactive protein in the body, and it is good practice to have this checked during routine medical checkups. Research indicates that foods high in magnesium (e.g. almonds, spinach, cashews, black beans, kelp, pumpkin seeds, etc.) can help reduce inflammation and elevated levels of C-reactive protein.

Maintaining a proper balance between omega-3 and omega-6 fatty acids can also help to reduce the risk of inflammation. The typical western diet is deficient in omega-3 fatty acids, and has excessive amounts of omega-6 fatty acids. Research has indicated that excessive amounts of omega-6 fatty acids and a very high omega-6/omega-3 ratio, as is found in today's Western diets, promotes many diseases, including cardiovascular disease, cancer, and inflammatory and autoimmune diseases.

One study found that a ratio of 2.5/1 (omega-6 / omega-3) reduced rectal cell proliferation in patients with colorectal cancer, whereas a ratio of 4/1 with the same amount of omega-3 had no such effect. Studies indicate that the optimal ratio may vary by disease.

The bottom line is that reducing the level of chronic inflammation, assisted by a diet with a lower ratio of omega-6/omega-3 fatty acids is desirable in reducing the risk of many of the chronic diseases including cancer. To learn more see here - http://www.ncbi.nlm.nih.gov/pubmed/12442909

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Tambre Leighn's curator insight, April 28, 2014 5:49 PM

...and MORE data about the role of nutrition and physical activity in cancer prevention...

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Cancer is a Metabolic Disease that Responds to Diet-Based Metabolic Therapy

Cancer is a Metabolic Disease that Responds to Diet-Based Metabolic Therapy | Cancer - Advances, Knowledge, Integrative & Holistic Treatments | Scoop.it
Enjoy this free DigiVision Lecture from the ACAM 2013 conference in Hollywood Florida
Graham Player Ph.D.'s insight:

The belief of medical experts seems to be that cancer is a genetic disease. A belief that is expressed in our college education, biology textbooks, medical education, and top scientific journals. The belief is extended to suggest that if there is any metabolic component to the cause of cancer, then it is due to some genomic instability.

The origin of these beliefs dates back to 1914 with the work of Theodor Heinrich Boveri, a German biologist. However it turns out that he never actually studied cancer himself. Today many scientists have a different view of cancer and do not subscribe to the theory that cancer is genetic in origin. Cancer cells also are metabolically abnormal. Research has shown that transferring the nucleus of cancer cells into normal cells does not result in the normal cells becoming cancerous. Further research indicates that transferring normal mitochondria into cancer cells can also suppress the development of the cancer. This suggests that abnormalities which may exist in the nucleus, such as various genomic instabilities, are not the drivers of the cancer. These findings contradict the theory that the genes are driving the cancer.

So what does drive cancer? Typically the mitochondria in cancer cells are damaged and the integrity of their structure, and therefore function, is compromised. Some studies have shown that many tumor cells have no mitochondria. Thomas Seyfried , PhD, asserts that if the respiration function within the cell becomes damaged it can give rise to the development of cancer. Compromised respiration gives rise to increased fermentation which allows the cell to survive with defective respiration. His work, together with preclinical and case report studies, has led him to the conclusion that restricted diet can be an effective metabolic therapy for cancer, in place of the normal standard of care that involves radiation and chemotherapy.

Specifically he has found that the ketogenic diet is able to restrict and reduce cancer growth. It involves calorie restriction through lack (or severe restriction) of carbohydrates in the diet. The absence of glucose as a result of lack of carbohydrates is replaced by high fat content. The combination of lack of carbohydrates and high fat encourages the liver to make ketone bodies from the fats. The ketones become the food supply for the brain cells and other important organs such as the heart. Tumor cells cannot metabolize ketones so they gradually die off from lack of glucose.

However it is important that the ketogenic diet is maintained within restricted amounts. Unrestricted consumption of fats can have the effect of compromising the effect of insulin, and therefore result in high glucose levels which will then feed the cancer cells. Further, Dr. Seyfried has established that hyperbaric oxygen therapy together with the ketogenic diet has been found to have a very beneficial synergistic benefit on the reduction of cancer.

The process first involves getting people into the right metabolic state where their ketone production is increased and their glucose is reduced. This may involve a 3-day therapeutic fast, and then transition to a ketogenic diet. In this state the cancer cells become vulnerable to attack, and the normal cells are protected.

To learn more refer to Dr. Seyfried’s book “Cancer as a Metabolic Disease”.

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What Every Cancer Patient Needs to Know When They Are First Diagnosed With Cancer

Critical info for cancer patients.

Graham Player Ph.D.'s insight:

In this video (11 minutes) Chris, who cured his own stage 3 colon cancer without chemotherapy or radiation, answers a question that would benefit every cancer patient – what do you wish someone had told you when you were first diagnosed with cancer? I have included below what I felt are the important points.

Don’t Be Afraid

Being afraid is a normal reaction to a cancer diagnosis. The first reaction is to think you are dying. But you are not. Cancer is a normal process and the body is designed to recognize and eliminate cancer cells. The cancer itself is not the real problem for you. The main problem is that you have a systemic metabolic disease that is resulting in tumors growing in your body. The tumor is the symptom. If you simply take out the tumor your body will build another. Cancer results in a body that is nutrient deficient and overloaded with toxins, and typically the result of a suppressed or overloaded immune system.

Don’t let anyone rush you into surgery, chemotherapy or radiation. You have time. The majority of cancers are not life-threatening and not emergency situations. Most doctors will admit you have some time. The cancer diagnosis should be a wakeup call telling you that you need to radically change your life and focus on becoming healthy.


The following four factors will either promote your health or promote disease, depending on the choices you make. You have choices. You can turn your diseased body into a healthy body by changing your life and making wise choices. Doing so will give your body everything it needs to repair, regenerate and detoxify.


Diet

What causes the cancer are a number of factors, including the processed man-made food that we were not designed to eat. We are overfed but malnourished. We get plenty of protein, fats and carbohydrates. But we are not getting the much needed micronutrients, vitamins, minerals, enzymes, antioxidants and the phytonutrient compounds in fruits, vegetables and plants that support the body’s ability to heal. Instead we pollute our bodies with processed foods, artificial chemicals, flavors, texture-enhancers, artificial fats – i.e. non-natural food that essentially is poisoning and polluting us. What we need to eat are foods that come from the earth in their natural form. Obesity is the second leading cause of cancer. Being overweight results in your body being in a chronic state of inflammation.

Lifestyle

If you drink too much alcohol, smoke or take drugs it can result in cancer. Especially taking pharmaceutical drugs. Pharmaceutical drugs do not heal. They only mask and alleviate symptoms. The only way to true healing is through nutrition to give your body all the building blocks that it needs to repair and regenerate.

Exercise
If you are not active and moving you are not sending signals of life to your body to grow, to get stronger and to live.

Stress

Stress suppresses and destroys your immune system. This applies to stress from relationships, work, or over-exercise. Harboring negative emotional stress like unforgiveness and bitterness, jealousy, being judgmental and critical of others, will put your body in a chronic state of inflammation. Your stress hormones will be elevated which can lead to encouraging cancer.

So many people have made radical changes like the above to their life, and have reversed chronic disease conditions and cured their own cancers. The medical view of cancer is that it is a linear progression that will grow and spread all over your body. The latest clinical research has proven that to be false.


Learning from the experience of others who have overcome their own cancer should be a primary focus of cancer sufferers and their family and friends. It is important to take time, don’t let anyone rush you into something, and listen to your own instincts. Don’t do something you do not feel good about. It is your life, you are in control and you make your own decisions. You have options, and your body can heal itself. You are also encouraged to come to terms with your own spirituality and faith, and seek the path of healing.

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What is Cancer Coaching?

What is Cancer Coaching? | Cancer - Advances, Knowledge, Integrative & Holistic Treatments | Scoop.it

Btief online video presentation.

Graham Player Ph.D.'s insight:

A short video showing introduction to Naturally Cancer Free and Cancer Coach.

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Viagra May Increase Risk of Skin Cancer

Viagra May Increase Risk of Skin Cancer | Cancer - Advances, Knowledge, Integrative & Holistic Treatments | Scoop.it
AFP-Getty Images fileResearchers found that men who took Viagra were about 84 percent more likely to develop melanoma than men who didn’t.Men who use Viagra ...
Graham Player Ph.D.'s insight:

A preliminary study, by Warren Alpert Medical School at Brown University, of 26,000 men found that men who took sildenafil (best known as Viagra) were 84% more likely to develop melanoma than men who didn’t take the drug.

Viagra may increase the risk of melanoma because it affects the same genetic pathway that allows the skin cancer to become more invasive, according to Dr. Abrar Qureshi, professor and chair of the dermatology department and co-author of the study.

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Lung Cancer 5-Year Survival Rates Very Low at Less Than 10%

Lung Cancer 5-Year Survival Rates Very Low at Less Than 10% | Cancer - Advances, Knowledge, Integrative & Holistic Treatments | Scoop.it
Graham Player Ph.D.'s insight:

A report on cancer survival rates from Macmillan Cancer Support analyzed 85,000 cancer patients' experiences of the NHS in England from 2004 to 2011 and showed some interesting statistics:

- one in five people with lung cancer die within one month of being diagnosed and 73% die within one year

- those who survive lung cancer for five years are then 10 times more likely to get another cancer

- one in five (20%) women with breast cancer and one in four (25%) men with prostate cancer survived for at least seven years after diagnosis

According to Cancer Research UK, lung cancer rates among women in the UK have risen by 73% since 1975, while falling by 47% among men. The highest rates in England are found in the north, while the lowest rates are in the east, south-east and south-west. In Scotland, lung cancer rates in women have almost doubled over the past 40 years and are among the highest in the world.

Fewer than 10% of people diagnosed with lung cancer survive for five years or more after diagnosis, according to Cancer Research UK.

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Aspirin May Extend Lives and Prevent Metastasis of Colorectal Cancer Patients

Aspirin May Extend Lives and Prevent Metastasis of Colorectal Cancer Patients | Cancer - Advances, Knowledge, Integrative & Holistic Treatments | Scoop.it
Researchers found that aspirin can improve outcomes in colon cancer patients.
Graham Player Ph.D.'s insight:

Patients with colon cancer could extend their lives by regularly using aspirin, according to a study of the tissue of 999 patients with colon cancer who had received surgery between 2002 and 2008.

Aspirin-associated survival was strongest in patients with HLA I antigen expression. Researchers are not sure about the molecular reasoning behind the improved survival rate, but it could have to do with aspirin's effect on "circulating tumor cells and their ability to develop into metastatic deposits," the news release reported. In contrast, in patients whose tumors had lost their HLA class I antigen expression, aspirin use did not change the outcome.

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High Protein Diet Significantly Increases Cancer Risk

High Protein Diet Significantly Increases Cancer Risk | Cancer - Advances, Knowledge, Integrative & Holistic Treatments | Scoop.it
Protein-rich diets are linked to an early death, especially from cancer. But there are caveats.
Graham Player Ph.D.'s insight:

A study by the Longevity Institute at the University of Southern California followed over 6,300 adults over the age of 50, to see what effect high-, medium-, and low-protein diets had on longevity.

People from ages 50-65 who ate high-protein diets were four times more likely to die of cancer compared to those who ate low-protein diets. Even those who ate moderate-protein diets were three times as likely to die from cancer. And people who ate high-protein diets were 75% more likely to die from any cause, including three times as likely to die from diabetes.


The source of the protein was found to make a difference. If the source was not animal derived protein the mortality risk was significantly reduced. Plant-based protein did not seem to present the same kind of problem as protein from animal sources.


Protein intake influences the levels of the growth hormone IGF-I, which not only affects the growth of healthy cells, but can also encourage cancer cell growth. In the study, the team found that for every 10 ng/ml increase in IGF-I, people who ate high-protein diets were 9% more likely to die from cancer than those on a low-protein diet. IGF-I levels naturally decline over the years, especially after age 65, which is part of the reason that people lose muscle tone and become frailer with age.


Many studies have shown that a plat-based diet has more health benefits.

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Frankincense Potential Treatment for Cancer

University of Leicester researchers discover cancer-killing properties of frankincense in ovarian cancer
Graham Player Ph.D.'s insight:

Researchers from the University of Leicester have demonstrated the potential of treating ovarian cancer using frankincense. The research funded by the Omani government has successfully shown its potential effectiveness in targeting ovarian cancer.

Previous studies have identified frankincense as a potential treatment for many other cancers, including colon, breast and prostate cancer. However this is the first study to demonstrate its potential in combatting ovarian cancer.

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High Vitamin D Level Found to Double Chance of Breast Cancer Survival

High Vitamin D Level Found to Double Chance of Breast Cancer Survival | Cancer - Advances, Knowledge, Integrative & Holistic Treatments | Scoop.it

Research published in The International Journal of Cancer Research and Treatment concludes that high serum 25(OH)D was associated with lower mortality from breast cancer.

 

Graham Player Ph.D.'s insight:

A study of women with breast cancer reveals that breast cancer patients who had high levels of vitamin D were twice as likely to survive as women with low levels.

Laboratory studies have demonstrated anticancer effects of vitamin D metabolites on three critical phases in the development of breast tumors: differentiation, apoptosis, and angiogenesis. It is possible that the association of serum 25(OH)D with survival depends on maintaining differentiation, promoting apoptosis, and inhibiting angiogenesis.


While most studies have focused on the relationship between vitamin D and incidence of breast cancer, only a few studies have investigated the possible relationship between serum 25-hydroxyvitamin D 25(OH)D status and cancer survival rates.

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The Gerson Therapy: An Alternative Cancer Treatment

The Gerson Therapy: An Alternative Cancer Treatment | Cancer - Advances, Knowledge, Integrative & Holistic Treatments | Scoop.it
Each year, about 14 million  people around the world are diagnosed with cancer. Of those  diagnosed, almost 8 million will die. It has taken many lives too early. 
Graham Player Ph.D.'s insight:

The Gerson therapy is a holistic approach to cancer. It is a natural treatment that utilizes natural supplements, raw juices, coffee enemas and an organic and vegetarian diet to allow the body to heal itself. Its emphasis is to detoxify the body and boost the immune system.

The therapy involves a low-salt, low-fat and low-protein diet. It is strictly vegetarian, and only organically grown fruits and vegetables are consumed. The goal is for the body to ingest between 15-20 pounds of organically grown fruits and vegetables on a daily basis. Juicing is an important part of the diet, and the regiment consists of drinking 13 glasses of fresh raw juice every day. Supplements such as vitamin B12, thyroid hormones and pancreatic enzymes are also taken.

The Gerson Institute does not own a treatment center but has two licensed privately owned business clinics, in Mexico and Hungary, where patients are referred. The cost for the recommended two-week stay at their clinics, which has to be paid up-front, is US$11,000 and does not include travel expenses. Additionally, the supplements, products and necessities required to continue the therapy at home are between US$2,000-US$4,000. 

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Dr. Frankel Comments on Cannabis and Cannabinoids in Cancer Treatment

http://articles.mercola.com/sites/articles/archive/2014/03/09/medical-cannabis.aspx Natural health physician and Mercola.com founder Dr. Joseph Mercola inter...
Graham Player Ph.D.'s insight:

Here is an interview with Dr. Allan Frankel who is a medical practitioner in California with expertise in the use of cannabis for cancer. He will tell you how he sees the shrinking of tumors and metastases disappearing as a result of using medicinal cannabis.

I recommend this interview to anybody who wants to know more about this subject. In addition Dr, Frankel’s website has particularly useful information - http://www.greenbridgemed.com/

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Cannabis is Known To Cure and Prevent Cancer

Please Re-Upload and Share this Video with Everyone! Health Professionals, Doctors and Scientists Interviewed They are listed in order of appearance in this ...
Graham Player Ph.D.'s insight:

According to Dr. Jeffrey Hergenrather M.D., President of the Society of Cannabis Clinicians, there is a wealth of laboratory evidence that the anti-tumor properties of cannabis kills cancer cells in a variety of ways. Cannabis actually stimulates a system in the body that is already present – the endo-cannabinoid system – due to the influence of the cannabinoids, the components of the cannabis.

There are multiple mechanisms of action identified by which cannabis kills cancer cells, and they are divided into various categories. Among these are anti-proliferative effects (inhibiting the reproduction of cancer cells), anti-angiogenesis effects (inhibiting the growth of new blood vessels needed by the tumor to grow), anti-metastatic effects (inhibiting cancer spread into other tissues), apoptotic effect (speeding the death of abnormal cancer cells).

Research has shown that in tumors, cancer cells are killed by marihuana while other healthy cells are left untouched. Dr. Manuel Guzman Professor of Biochemistry at the University of Madrid is known for his ground-breaking studies on medical cannabis and confirms that cannabinoids have the effect of inducing cell death in cancer cells. They inhibit the growth and multiplication of cancer cells and they actually reduce the growth of tumors.

So why aren’t funds being directed towards research of this natural product? In fact much of the research that is occurring is being done outside of the USA.

A UK study confirms that compounds derived from cannabis can kill cancerous cells. The study analyzed the effects of six different non-psychoactive purified cannabinoids compounds from marijuana - CBD (cannabidiol), CBDA (cannabidiolic acid), CBG (cannbigerol), CBGA (cannabigerolic acid), CBGV (cannabigevarin) and CBGVA (cannabigevaric acid). It did not include THC (tetrahydrocannabinol) which is the psychoactive compound from marijuana. I reported here last August on 34 medical studies for cancer therapy, as well as other information on the subject.

So how does the endocannabinoid system function in terms of cancer. It is an essential physiologic system involved in maintaining human health via complex actions in our immune system, nervous system, and organs. The endocannabinoid system consists of cannabinoid receptors which can be found in cell membranes throughout the entire body. When a cell is cancerous there is an increase in the number of cannabinoid receptors in the cell. The body’s own immune system can sense this increase and produce its own endogenous cannabinoid neurotransmitter called anandamide.

Anandamide mates with these cannabinoid receptors and stimulates the production of a chemical called ceramide which plays a critical role in programmed cell death. The job of ceramide in the normal body is to kill damaged and dying cells. When ceramide is produced in the cancer cell it kills off the mitochondria which are the cells’ power producers. Once the mitochondria are dead then the cell can no longer survive.

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Beth A. Williams's curator insight, September 30, 2014 10:21 AM

This provides an amazing look at not only the beneficial effects of cannabis on existing tumors, including brain tumors, but also the prevention aspects. Even tobacco smoking was compared with cannabis smoking. Even so, there are many barriers in this country to break down before such research and solutions become available to a broad array of cancer patients. Looking forward to more conclusive data. Again, no nasty side effects associated with herbal cannabis! If I were in active treatment today, I would be aggressively looking into this as a treatment option.

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Inadequate Sleep Can Promote and Speed Cancer Growth

Inadequate Sleep Can Promote and Speed Cancer Growth | Cancer - Advances, Knowledge, Integrative & Holistic Treatments | Scoop.it

Poor-quality sleep marked by frequent awakenings can speed cancer growth, increase tumor aggressiveness and dampen the immune system's ability to control or eradicate early cancers, according to a new study published online January 21, 2014, in the journal Cancer Research.

Graham Player Ph.D.'s insight:

Many health problems are associated with lack of sleep. A new study shows that inadequate sleep can speed the growth of cancer.

According to the study, on an animal model, published in the journal Cancer Research, poor-quality sleep marked by frequent awakenings can speed cancer growth, increase tumor aggressiveness and dampen the immune system's ability to control or eradicate early cancers.

The study director David Gozal, MD, chairman of pediatrics at the University of Chicago Comer Children's Hospital, commented that "fragmented sleep changes how the immune system deals with cancer in ways that make the disease more aggressive."

This study provides biological credibility in terms of the association between compromised sleep and cancer outcomes.

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Tambre Leighn's curator insight, April 28, 2014 5:50 PM

Get your zzz's...part of a healthy immune system for prevention.

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UK Skin Cancer Rates Increase 500%

UK Skin Cancer Rates Increase 500% | Cancer - Advances, Knowledge, Integrative & Holistic Treatments | Scoop.it

More than 13,000 people are now developing malignant melanoma each year, Cancer Research UK figures reveal

Graham Player Ph.D.'s insight:

Rates of malignant melanoma, the most dangerous form of skin cancer, are five times higher in the UK today than they were in the 1970s. This is partly down to the increase in package holidays to sunny European destinations, and a boom in sunbed use.


Sunburn is known to increase the risk of skin cancer, especially in people with pale skin or large numbers of moles or freckles.

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75% Less Cancer Deaths with Vitamin D

Possible 75% Less Cancer Deaths with Vitamin D with Carole Baggerly and Dr. Cedric Garland.

Graham Player Ph.D.'s insight:

I can’t emphasize enough that ongoing research confirms the beneficial effects of Vitamin D for cancer prevention and saving lives of cancer sufferers.

This is not a new discovery and has been advocated by many researchers and scientists for many years. For those with an interest in cancer or cancer prevention please do your own research or look through the references to Vitamin D here throughout my topic.

An article published way back in 2009 in the Annals of Epidemiology projected that raising the minimum year-around serum 25(OH)D level (i.e. Vitamin D level in the blood) to 40 to 60 ng/mL (100–150 nmol/L) would prevent approximately 58,000 new cases of breast cancer and 49,000 new cases of colorectal cancer each year, and 75% of deaths from these diseases in the United States and Canada. It is beneficial for colon, breast, ovarian, renal, pancreatic, aggressive prostate and other cancers. Here is the article - http://www.annalsofepidemiology.org/article/S1047-2797%2809%2900105-7/abstract .

In the video (5m 37s) Dr. Cedric Garland explains further.

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Simple Blood Test for Solid Cancer May be Effective

Simple Blood Test for Solid Cancer May be Effective | Cancer - Advances, Knowledge, Integrative & Holistic Treatments | Scoop.it
A US team has developed an ultra-sensitive way of detecting tumor DNA in the bloodstream, bringing closer the prospect of a simple general blood test for diverse solid cancers.
Graham Player Ph.D.'s insight:

Researchers from Stanford University School of Medicine have devised an ultra-sensitive method for finding DNA from cancer tumors in the bloodstream. The new method identified around half of patients with stage 1 lung cancer and all patients with stage 2 or higher disease.

Cancer cells divide and die, even without treatment. When a cancer cell dies, the DNA in its nucleus escapes into the bloodstream. This is present in small concentrations - something like 1 in 1,000 or 10,000 bits of DNA in the blood can be from a dead cancer cell in a person with cancer.

So a test that can quickly and non-invasively monitor the tiny concentrations of cancer cell DNA would be really useful to clinicians who need to estimate the size of the tumor, how it changes over time, and monitor a patient's response to treatment.



The team found a way to do this by boosting existing methods for extracting, processing and analyzing the DNA. They called their approach CAPP-Seq (which is short for Cancer Personalized Profiling by deep Sequencing).

The researchers say CAPP-Seq may also have potential as a prognostic tool. When they tested one patient thought to have been successfully treated for lung cancer, they found low levels of circulating tumor DNA. The cancer came back in that patient, and they died

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Fukushima's Radiation Victims – Despite Cancer Rates of Four Times the World Average, Authorities Refuse to Publish Details

Fukushima's Radiation Victims – Despite Cancer Rates of Four Times the World Average, Authorities Refuse to Publish Details | Cancer - Advances, Knowledge, Integrative & Holistic Treatments | Scoop.it
The residents of the evacuated Japanese town of Namie near the crippled nuclear plant in Fukushima were contaminated with radiation. They have now taken the responsibility for their health into their own hands.
Graham Player Ph.D.'s insight:

At the time of the Fukushima nuclear plant incident in Japan, inhabitants of Namie, located nine kilometres (5.6 miles) north of the nuclear plant, were ordered to leave their homes.

In his medical practice in the city of Nihonmatsu, where around 230 relocated families from Namie are situated in a settlement, Dr. Shunji Sekine has been examining the thyroid glands of Namie citizens on a daily basis ever since the nuclear incident three years ago. He sees a direct connection between the nuclear accident and the unusually high occurrence of cancer.

According to official figures, 33 cancer cases have been identified in about a quarter of a million children and teenagers since the beginning of February. This translates into 13 cases for every 100,000 inhabitants, a figure almost four times higher than the world average for all age groups.

Despite these facts, the government of Fukushima refuses to publish any relevant details about the prevalence of cancer, and Japan’s top thyroid expert and health advisor to the prefectural government plays down the issue.

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Radiation Treatment in Children with Glioma Tumors Linked to Increased Death Rates

Radiation Treatment in Children with Glioma Tumors Linked to Increased Death Rates | Cancer - Advances, Knowledge, Integrative & Holistic Treatments | Scoop.it
Almost 90 percent of children treated for low-grade gliomas are alive 20 years later and few die from the tumor as adults. However, children whose treatment included radiation had significantly lower long-term survival rates.
Graham Player Ph.D.'s insight:

Gliomas are the most common brain tumors in children. The tumors start in the brain or spine and are categorized according to their grade. Low-grade gliomas are benign, yet may recur and become high-grade malignant tumors.

A study of the long-term survival of children treated for low-grade gliomas found that almost 90% are alive 20-years later and that few die from the tumor as adults. However, children who received radiation as part of their treatment had significantly lower long-term survival rates than children who were not radiated.

The study's senior author, Peter Manley, MD, of the Brain Tumor Center at Dana-Farber/Boston Children's commented that survival of low-grade glioma in childhood means you are not likely to die of that tumor as an adult, unless radiation has been administered.

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Amazing Results Indicate That Hyperthermia Has the Ability to Activate an Anti-Tumor Immune System Response and Eradicate Cancer Cells

Amazing Results Indicate That Hyperthermia Has the Ability to Activate an Anti-Tumor Immune System Response and Eradicate Cancer Cells | Cancer - Advances, Knowledge, Integrative & Holistic Treatments | Scoop.it

Combined use of iron oxide nanoparticles and an alternating magnetic field can induce local hyperthermia in tumors in a controlled and uniform manner.

Graham Player Ph.D.'s insight:

Surgical removal of tumors does not guarantee the removal of every cancer cell, especially when there is unrecognized metastases in other anatomic locations. What if there was a procedure that was able to remove one tumor and then trigger an automatic immune response that meant the body itself removed any remaining tumors?

Well that procedure may have been discovered by researchers at Dartmouth-Hitchcock Norris Cotton Center. The researchers found that controlled heating of one tumor can stimulate an immune response that attacks other tumors that have not had the heat treatment.

This immune system response was produced by injecting a combination of iron-oxide nanoparticles and an alternating magnetic field into one tumor, which then generated heat and activated antigen-presenting dendritic cells that triggered the immune system response to attack other tumors.

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Vitamin D Shown to Improved Breast Cancer Survival Rates

Vitamin D Shown to Improved Breast Cancer Survival Rates | Cancer - Advances, Knowledge, Integrative & Holistic Treatments | Scoop.it
Breast cancer patients with high levels of vitamin D in their blood may be more likely to survive the disease compared to women lacking the nutrient, a new study reports.
Graham Player Ph.D.'s insight:

Researchers from the University of California, San Diego School of Medicine analyzed vitamin D levels in a group of 4,443 breast cancer patients involved in five separate studies. They found that women with high levels of vitamin D were twice as likely to survive their disease compared to women with low levels of the vitamin in their blood.

Study author Cedric F. Garland, a professor in the Department of Family and Preventive Medicine at UC San Diego explains that Vitamin D metabolites increase communication between cells by switching on a protein that blocks aggressive cell division. So as long as vitamin D receptors are present tumor growth is prevented and kept from expanding its blood supply. Vitamin D receptors are not lost until a tumor is very advanced. This is the reason for better survival in patients whose vitamin D blood levels are high.

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Higher Cancer Risk for Kids Living Near Busy Roads

Higher Cancer Risk for Kids Living Near Busy Roads | Cancer - Advances, Knowledge, Integrative & Holistic Treatments | Scoop.it
A CDC review of previous studies suggests a link between childhood leukemia and exposure to elevated levels of traffic-related air pollutants; more study is needed to establish cause-effect, researchers say.
Graham Player Ph.D.'s insight:

Young children who are exposed to high levels of vehicle exhaust — such as what they'd encounter living near busy roads in urban areas — appear to have a greater risk of childhood leukemia, according to a Centers for Disease Control and Prevention review of seven previous studies.

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Weight Increase Linked to Higher Ovarian Cancer Risk

Weight Increase Linked to Higher Ovarian Cancer Risk | Cancer - Advances, Knowledge, Integrative & Holistic Treatments | Scoop.it

A new report finds a probable link between being overweight and an increased risk of ovarian cancer.

Graham Player Ph.D.'s insight:

A report published by the American Institute for Cancer Research and World Cancer Research Fund, analyzed several ovarian cancer studies conducted globally and found a probable link between being overweight and an increased risk of ovarian cancer. The report found the risk of ovarian cancer rose 6% for every increased 5 BMI units.

Thomas Krivak, director of clinical research in gynecologic oncology at West Penn Allegheny Health System, called the findings "enticing," but "not earth-shattering." He said ovarian cancer prevalence has not increased at the same rate as obesity, and that although the number sounds high, a woman's lifetime risk of developing ovarian cancer is 1.5%. A 6% increase puts her risk at 1.59% over her lifetime.

Nevertheless being overweight is generally considered to increase one’s likelihood of chronic disease including cancer.

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Tambre Leighn's curator insight, April 28, 2014 5:54 PM

Wow...the last four articles on my scoop it newsfeed all highlighting healthy lifestyle behaviors as prevention....nutrition, reduced stress, sleep, healthy weight.  Choices that support a healthy lifestyle, increased immune health = opportunity, responsibility to ourselves to follow through.

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A Gene Family That Suppresses Prostate Cancer

A Gene Family That Suppresses Prostate Cancer | Cancer - Advances, Knowledge, Integrative & Holistic Treatments | Scoop.it
Cornell University researchers report they have discovered direct genetic evidence that a family of genes, called MicroRNA-34 (miR-34), are bona fide tumor suppressors.
Graham Player Ph.D.'s insight:

It is well accepted that mutations of the p53 gene have been implicated in half of all cancers. Research in mice has revealed how interplay between genes p53 and miR-34 (MicroRNA-34) jointly inhibits another cancer-causing gene called MET. In absence of p53 and miR-34, MET overexpresses a receptor protein and promotes unregulated cell growth and metastasis.

In mice that had both miR-34 and p53 silenced concurrently, cancerous lesions formed in a proximal part of the prostrate ducts, in a compartment known to contain prostate stem cells. The early lesions that developed when p53 was silenced alone occurred in a distal part of the ducts, away from the compartment where the stem cell pool is located. This suggested there was another mechanism involved when p53 and miR-34 were jointly silenced.

These findings suggest that drug therapies that target and suppress MET could be especially successful in cancers where both p53 and miR-34 are deficient. This is the first time this mechanism has been proven in a mouse model, said Alexander Nikitin, a professor of pathology in Cornell's Department of Biomedical Sciences. "These results indicated that together miR-34 and p53 regulate the prostate stem cell compartments," said Nikitin.

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Death of Five Cancer Patients Casts Concerns on Laparoscopic, or Keyhole, Surgery Techniques

Death of Five Cancer Patients Casts Concerns on Laparoscopic, or Keyhole, Surgery Techniques | Cancer - Advances, Knowledge, Integrative & Holistic Treatments | Scoop.it
Surgery for a range of cancers has been suspended at an NHS hospital after five patients died from “potentially avoidable” complications. The widow of one patient who died said that her husband had been treated like “a human guinea pig” for a new surgery technique. 
Graham Player Ph.D.'s insight:

An investigation by the Royal College of Surgeons of the Maidstone Hospital in Kent revealed higher than expected rate of complications following surgery in 2012 and last year. As a result the hospital will not perform upper gastrointestinal (GI) cancer surgery – for cancers of the stomach, esophagus, liver and pancreas – for up to 12 months.

An internal review found that up to five patients may have died as a result of “potentially avoidable” complications, which were linked to the use of laparoscopic, or keyhole, surgery techniques

The widow of a 51-year-old esophageal cancer patient, who received surgery to remove a tumor in 2013, has now launched a clinical negligence claim. Solicitor Sharon Lam, acting for the widow, said that there were “serious questions” about the reliability of the procedure in question, and that the main concern is that the deceased could have opted for a more conventional procedure, but this particular procedure was highly advocated by the surgeon.

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