Cancer - Advances, Knowledge, Integrative & Holistic Treatments
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Cancer - Advances, Knowledge, Integrative & Holistic Treatments
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Autism Has Connection to Cancer Gene

Autism Has Connection to Cancer Gene | Cancer - Advances, Knowledge, Integrative & Holistic Treatments | Scoop.it
A gene known as PTEN can cause a number of cancers, and some 10% of kids with mutations in the gene have autism.
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The gene PTEN can cause a number of different cancers, including breast, thyroid, and colon; and it turns out that some 10% of kids with mutations in the gene have autism.

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Possibility of Targeted Gene Therapy for Prostate Cancer

Possibility of Targeted Gene Therapy for Prostate Cancer | Cancer - Advances, Knowledge, Integrative & Holistic Treatments | Scoop.it
Scientists at Sanford-Burnham Medical Research Institute (Sanford-Burnham) have identified how an enzyme called PKCζ suppresses prostate tumor formation.
Graham Player Ph.D.'s insight:

Scientists at Sanford-Burnham Medical Research Institute (Sanford-Burnham) have identified how an enzyme called PKCzeta suppresses prostate tumor formation. The study was published April 1 in the Proceedings of the National Academy of Sciences.

 

Under normal circumstances PKCzeta controls the activation of a pro-tumor gene called c-Myc. However in prostate and other cancers PKCzeta levels are low, which then allows the gene c-Myc free to promote cell growth and the spread of cancer.

 

So restoring the level of the enzyme PKCzeta may be effective in suppressing prostate tumor formation. The study found that PKCzeta in combination with another gene PTEN is effective in suppressing tumors. However in prostate cancer it is common for the gene PTEN to be in a mutated form.

 

This now provides an opportunity to delve into gene therapy to see if there are ways to activate the enzyme PKCzeta while controlling the genes c-Myc and PTEN.

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