Cancer - Advances, Knowledge, Integrative & Holistic Treatments
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ATF3 Key Role in Breast Cancer Metastasis

ATF3 Key Role in Breast Cancer Metastasis | Cancer - Advances, Knowledge, Integrative & Holistic Treatments | Scoop.it
ATF3 expression in stromal mononuclear cells correlates with clinical outcomes and predicts death.
Graham Player Ph.D.'s insight:

The expression of activating transcription factor 3 (ATF3) - a protein encoded by the ATF3 gene – has been found by researchers to result in a worse clinical outcome for breast tumors.

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Stress Fuels Cancer

Stress Fuels Cancer | Cancer - Advances, Knowledge, Integrative & Holistic Treatments | Scoop.it
Daily Mail
Stress DOES have an impact on cancer: Anxiety switches on a gene that speeds ...
Daily Mail
Stress fuels cancer by triggering a 'master switch' gene which allows the disease to spread, according to new research.
Graham Player Ph.D.'s insight:

Researchers at Ohio State University have found that our own bodies help turn cancer against us by turning on a 'master switch' gene known as ATF3 which is expressed in response to stressful conditions in all types of cells.

Cancer cells somehow coax immune-system cells recruited to the site of a tumor to express ATF3 which promotes the immune cells to act erratically and give cancer an escape route to other areas of the body.

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Tambre Leighn's curator insight, August 24, 2013 2:40 PM

More evidence that identifying stress triggers and reducing stress are an incredibly important part of wellbeing.  For more information on how coaching using iPEC's (The Institute for Professional Excellence in Coaching) Energy Leadership(TM) Model can put you in the driver's seat of reducing your own stress, check out wellbeyondordinary.com and search "stress".  This is work I've been doing with cancer survivorship, caregivers and healthcare professionals for several years now.  Check out testimonials for insights into how cancer survivorship and caregiver (both personal and professional caregivers) can help.

Tambre Leighn's curator insight, September 7, 2013 3:30 PM

One of the key components we address when working with clients using the coaching paradigm created by iPEC (Institute for Professional Excellence in Coaching) founder, Bruce D. Schneider, is to help them understand the impact stress is having, what triggers it and how to reduce it.  

 

The Energy Leadership Index (tm) Assessment is a simple online assessment tool that shows an individual's stress reaction in a quantifiable, measurable way.  Stress impacts our health, wellbeing, ability to perform, our success and our ability to create new behaviors when we want to make lifestyle behavior changes.  Stress reduction needs to become a top priority to help support prevention, wellbeing and the opportunity for people to live happier, more fulfilling lives.