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Jellyfish tentacles inspire DNA chains to snag roving cancer cells - Los Angeles Times

Jellyfish tentacles inspire DNA chains to snag roving cancer cells - Los Angeles Times | BS2040: Bioinformatics | Scoop.it
ExtremeTechJellyfish tentacles inspire DNA chains to snag roving cancer cellsLos Angeles TimesThus inspired, they designed a device with long chains of DNA made out of aptamers, or repeating, 'sticky' blocks of DNA, that could specifically latch on...
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BS2040: Bioinformatics
The fascinating fast moving world of bioinformatics scooped for BS2040. This scoop.it topic was formerly known as BS2064: Bioinformatics!
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One cell is all you need

One cell is all you need | BS2040: Bioinformatics | Scoop.it
Scientists at Harvard have pioneered a breakthrough technique that can reproduce an individual’s entire genome from a single cell.
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Why Science Needs to Publish Negative Results | SciTech Connect

Why Science Needs to Publish Negative Results | SciTech Connect | BS2040: Bioinformatics | Scoop.it
Emma Granqvist, a journal Publisher for Elsevier’s plant sciences, explains why publishing negative results is fundamentally important in science.
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NIH Director Hails “Stunning Case” as Example of Genomic Revolution | Xconomy

NIH Director Hails “Stunning Case” as Example of Genomic Revolution | Xconomy | BS2040: Bioinformatics | Scoop.it
A pregnant mom who got a non-invasive prenatal test because she knew at age 40 that her baby was a higher risk for Down syndrome has become a case study in
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I had my DNA tested, here’s what I found out

I had my DNA tested, here’s what I found out | BS2040: Bioinformatics | Scoop.it
Consumer genetic tests can be reassuring — or not — so think carefully before you learn your risk of developing an awful disease If you have a potentially life-altering genetic defect — but no symptoms — do you want to know?
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Two Strains of HIV Cut Vastly Different Paths - New York Times

Two Strains of HIV Cut Vastly Different Paths - New York Times | BS2040: Bioinformatics | Scoop.it
Researchers traced the origins of two subtypes of H.I.V.-1. One subtype stayed in Cameroon; the other spread throughout the world.
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Finished Drosophila Genetics Wall-hanging

Finished Drosophila Genetics Wall-hanging | BS2040: Bioinformatics | Scoop.it
Kellie and I have now finished and hung the hanging wall pockets that describe the Drosophila hox genes. I think it looks awesome!
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Unified Representation of Genetic Variants

Unified Representation of Genetic Variants | BS2040: Bioinformatics | Scoop.it
Unified Representation of Genetic Variants: http://t.co/BX2R6FkFib
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BMC Bioinformatics | Abstract | Inferring bona fide transfrags in RNA-Seq derived-transcriptome assemblies of non-model organisms

De novo transcriptome assembly of short transcribed fragments (transfrags) produced from sequencing-by-synthesis technologies often results in redundant datasets with differing levels of unassembled, partially assembled or mis-assembled transcripts.
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RNA-seq still proving that it is tricky to realise the full potential of new technologies...
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Regions outside the DNA-binding domain ... - PubMed Mobile - NCBI

Nucleic Acids Res. 2014 Jan;42(1):276-89. doi: 10.1093/nar/gkt895. Epub 2013 Oct 7. Research Support, Non-U.S. Gov't
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UNSW scores world first for fruit fly genetics | UNSW Newsroom

UNSW scores world first for fruit fly genetics | UNSW Newsroom | BS2040: Bioinformatics | Scoop.it
RT @UNSW: RT @LBSHorticulture: UNSW scores world first for fruit fly genetics - http://t.co/Bziho7R1XV @UNSW
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The Lab and the Literature: Driving Personalized Medicine

The Lab and the Literature: Driving Personalized Medicine | BS2040: Bioinformatics | Scoop.it
Both the amount and quality of generated data are challenges personalized medicine must conquer to become the norm in practiced medicine.
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Fossil Skull Suggests Humans and Neanderthals Lived Side by Side in the Middle East | IFLScience

Fossil Skull Suggests Humans and Neanderthals Lived Side by Side in the Middle East | IFLScience | BS2040: Bioinformatics | Scoop.it
A 55,000-year-old skull unearthed in an Israeli cave is the first Homo sapiens fossil discovered outside of Africa shortly after our species began exploring different continents.
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Jumping DNA and the Evolution of Pregnancy – Phenomena: Not Exactly Rocket Science

Jumping DNA and the Evolution of Pregnancy – Phenomena: Not Exactly Rocket Science | BS2040: Bioinformatics | Scoop.it
About a decade ago, Vincent Lynch emailed Frank Grutzner to ask for a tissue sample from a pregnant platypus. He got a polite brush-off instead. Then, around eight years later, Grutzner got back in...

Via Chris Upton + helpers
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This is a must read paper for me!

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Gilbert Faure au nom de l'ASSIM's curator insight, February 3, 4:20 AM

nice approach, would have been difficult to finance as a big classical clinical research project

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Oldest Neanderthal DNA found in Italian skeleton

Oldest Neanderthal DNA found in Italian skeleton | BS2040: Bioinformatics | Scoop.it
The calcite-encrusted skeleton of an ancient human, still embedded in rock deep inside a cave in Italy, has yielded the oldest Neanderthal DNA ever found
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A conversation with George Church on Genomics & Germline Human Genetic Modification

A conversation with George Church on Genomics & Germline Human Genetic Modification | BS2040: Bioinformatics | Scoop.it
I recently interviewed leading genomics scientist George Church on the ways that trends in genomics are changing our world and the possibility of heritable human genetic modification. His answers s...
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DNA Clears Nevada Woman Imprisoned 35 Years for Murder

DNA Clears Nevada Woman Imprisoned 35 Years for Murder | BS2040: Bioinformatics | Scoop.it
After the case was dropped against a Nevada woman who spent 35 years in prison for a 1976 murder she did not commit, both sides agreed on one point: justice was finally served thanks to new technology in DNA testing.
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The human pancreas proteome defined by transcriptomics and antibody... - PubMed - NCBI

PLoS One. 2014 Dec 29;9(12):e115421. doi: 10.1371/journal.pone.0115421. eCollection 2014. Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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DNA documents ancient mass migration

DNA documents ancient mass migration | BS2040: Bioinformatics | Scoop.it
DNA analysis has revealed evidence for a massive migration into the heartland of Europe 4,500 years ago.
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Illumina Plans to Tap Consumer Market for its Smartphone-Ready DNA Chip: Will This Create Diagnostic Consulting Opportunities for Pathologists? | Dark Daily

Illumina Plans to Tap Consumer Market for its Smartphone-Ready DNA Chip: Will This Create Diagnostic Consulting Opportunities for Pathologists? | Dark Daily | BS2040: Bioinformatics | Scoop.it
In the field of next-generation gene sequencing, San Diego, California-based Illumina, Inc., (NASDAQ: ILMN) is moving expeditiously to expand into related markets.
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The Body's Transformers: Some Proteins Can Alter Their Configuration

The Body's Transformers: Some Proteins Can Alter Their Configuration | BS2040: Bioinformatics | Scoop.it
Santa Barbara, CA (Scicasts) — Like the shape-shifting robots of "Transformers" fame, a unique class of proteins in the human body also has the ability to alter their configuration.
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Identifying the Biological Basis of GWAS Hits for Endometriosis

Review by Montgomery et al "IDing Biological Basis of GWAS Hits for Endometriosis" http://t.co/Lrmbtv6mMp @QIMRBerghofer @unimelb #BORreview
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DNA banking offers potential for funeral homes

DNA banking offers potential for funeral homes | BS2040: Bioinformatics | Scoop.it
Service can play an important role in learning more about family ancestors.
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Transcriptomics identifies genes and signaling pathways that may regulate neurodegeneration

Transcriptomics identifies genes and signaling pathways that may regulate neurodegeneration | BS2040: Bioinformatics | Scoop.it
Neuronal death is a normal feature of brain development but also a defining feature of neurodegenerative diseases when improperly regulated.
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Inherited gene variations tied to treatment-related hearing loss in cancer patients

Inherited gene variations tied to treatment-related hearing loss in cancer patients | BS2040: Bioinformatics | Scoop.it
St. Jude Children's Research Hospital investigators have discovered inherited genetic variations that are associated with rapid hearing loss in young cancer patients treated with the drug cisplatin.
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BMC Bioinformatics | Full text | Improving protein fold recognition using the amalgamation of evolutionary-based and structural based information

Deciphering three dimensional structure of a protein sequence is a challenging task in biological science.
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The Consortium for Sequencing the Food Supply Chain | RNA-Seq Blog

The Consortium for Sequencing the Food Supply Chain | RNA-Seq Blog | BS2040: Bioinformatics | Scoop.it
IBM Research and Mars tackle global health with food safety partnership The significant threat of food borne illness affects nearly every industry on every
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