BS2064: Bioinformatics
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The fascinating fast moving world of bioinformatics scooped for BS2064
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Scooped by Dr Richard Badge
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One cell is all you need

One cell is all you need | BS2064: Bioinformatics | Scoop.it
Scientists at Harvard have pioneered a breakthrough technique that can reproduce an individual’s entire genome from a single cell.
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Mystery of 'junk DNA' solved | MNN - Mother Nature Network

Mystery of 'junk DNA' solved | MNN - Mother Nature Network | BS2064: Bioinformatics | Scoop.it
One person's trash may be another person's treasure, but sometimes, trash is just trash.
Dr Richard Badge's insight:

Of course genome size variation within genera has been known for while - just nice in this case the researchers identified retrotransposons as the "missing" junk...

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Painted turtle gets DNA decoded - Eureka! Science News

Painted turtle gets DNA decoded - Eureka! Science News | BS2064: Bioinformatics | Scoop.it
Eureka! Science News Painted turtle gets DNA decoded Eureka! Science News The western painted turtle lives in freshwater ponds and streams and is the most widespread turtle in North America.
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Giant squid genetics reveal family secrets - PakistanToday.com.pk

Giant squid genetics reveal family secrets - PakistanToday.com.pk | BS2064: Bioinformatics | Scoop.it
PakistanToday.com.pk
Giant squid genetics reveal family secrets
PakistanToday.com.pk
They then used DNA sequencing techniques to understand the genetic makeup of the squid. Results revealed that the squid are all one species.
Dr Richard Badge's insight:

Surprising lack of diversity in a species with pelagic larvae...?

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Elements of Bioinformatics table – now with Search! | Eagle Genomics

Elements of Bioinformatics table – now with Search! | Eagle Genomics | BS2064: Bioinformatics | Scoop.it
We released a new version of our Elements of Bioinformatics table this morning - otherwise known as the Periodic Table of Bioinformatics. There's been a few.
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DNA-inspired twisting Agora Garden underway in Taipei City - Gizmag

DNA-inspired twisting Agora Garden underway in Taipei City - Gizmag | BS2064: Bioinformatics | Scoop.it
DNA-inspired twisting Agora Garden underway in Taipei City Gizmag Construction on this unusual twisting tower, named Agora Garden, recently began in Taipei City , according to its designer Vincent Callebaut Architecte.
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Sweden joins European DNA data-sharing system - The Local.se

Sweden joins European DNA data-sharing system - The Local.se | BS2064: Bioinformatics | Scoop.it
Sweden joins European DNA data-sharing system The Local.se Online: http://www.thelocal.se/46652/20130310/. From the summer of 2013, Swedish police will be able to access other European Union nations' DNA databases - a move which is expected to...
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Researchers Solve Genetic Mystery of Rare Form of Haemophilia - Sci-News.com

Researchers Solve Genetic Mystery of Rare Form of Haemophilia - Sci-News.com | BS2064: Bioinformatics | Scoop.it
Researchers Solve Genetic Mystery of Rare Form of Haemophilia Sci-News.com An international team of genetic researchers led by Prof Merlin Crossley from the University of New South Wales has found the third and final missing piece in the genetic...
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BMC Bioinformatics | Abstract | Hydra: a scalable proteomic search engine which utilizes the Hadoop distributed computing framework

For shotgun mass spectrometry based proteomics the most computationally expensive step is in matching the spectra against an increasingly large database of sequences and their post-translational modifications with known masses.
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Illumina reveals bid for Complete Genomics - MarketWatch

Illumina reveals bid for Complete Genomics - MarketWatch | BS2064: Bioinformatics | Scoop.it
Illumina reveals bid for Complete GenomicsMarketWatchComplete Genomics agreed in September to be acquired by BGI-Shenzhen. The companies had said they expect to complete the transaction in early 2013.
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Police Request DNA to Solve Case, Murderer Submits His Own ...

Police Request DNA to Solve Case, Murderer Submits His Own ... | BS2064: Bioinformatics | Scoop.it
After 16-year-old Marianne Vaatstra was raped and murdered in the Netherlands in 1999, the case quickly went nowhere. Those responsible were were never found, though the police conducted a thorough investigation.
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Health News - Gene Nearly Triples Risk of Alzheimer's, Global Team Including Mayo Clinic Finds

Gene Nearly Triples Risk of Alzheimer's, Global Team Including Mayo Clinic Finds (Gene Nearly Triples Risk of Alzheimer's, Global Team Including Mayo Clinic Finds… http://t.co/bkvjxG3p...)...
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Troubled sequencing pioneer Helicos shelters in bankruptcy court - FierceBiotech

Troubled sequencing pioneer Helicos shelters in bankruptcy court - FierceBiotech | BS2064: Bioinformatics | Scoop.it
Delisted and largely dumped by investors after a pair of restructurings failed to cure what ailed it, Cambridge, MA-based Helicos BioSciences ($HLCS) has stepped into bankruptcy court seeking Chapter 11 protection for the genomic sequencing company.
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Sequencing Study IDs Spontaneous Mutations in Congenital Heart Disease - Genetic Engineering News

Sequencing Study IDs Spontaneous Mutations in Congenital Heart Disease - Genetic Engineering News | BS2064: Bioinformatics | Scoop.it
AFP Sequencing Study IDs Spontaneous Mutations in Congenital Heart Disease Genetic Engineering News Using next-generation sequencing, Yale School of Medicine's Richard Lifton and his colleagues compared the exomes of children with an without...
Dr Richard Badge's insight:

The mutations in histone metabolism genes could have complicated effects, but interesting that CHD patients enriched for heart expressed gene mutations...

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This Revolutionary DNA Extractor Cracks Your Genetics In Minutes - Gizmodo Australia

This Revolutionary DNA Extractor Cracks Your Genetics In Minutes - Gizmodo Australia | BS2064: Bioinformatics | Scoop.it
This Revolutionary DNA Extractor Cracks Your Genetics In Minutes Gizmodo Australia Pulling DNA from the cell that surrounds it may be a vital process to modern genomics, but it's also a cumbersome and time-consuming pain in the arse, “like...
Dr Richard Badge's insight:

 A really innovative approach - but still means you have to crack cells open!

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Exome sequencing identifies titin mutations causing hereditary myopathy with ... - 7thSpace Interactive (press release)

Exome sequencing identifies titin mutations causing hereditary myopathy with ...
Dr Richard Badge's insight:

Wow - titin is a giant protein (~30,000 amino acids) that has 363 exons!

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Designing better web experiences for bioinformatics - BMC Pediatrics (blog)

Designing better web experiences for bioinformatics - BMC Pediatrics (blog) | BS2064: Bioinformatics | Scoop.it
Designing better web experiences for bioinformatics
BMC Pediatrics (blog)
The latest issue of BMC Bioinformatics includes the first 'how to' guide for applying User-Centred Design (UCD) to websites for bioinformatics.
Dr Richard Badge's insight:

Had fun helping out with this (one of those "test users")

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DNA catalysts do the work of protein enzymes - Phys.Org

DNA catalysts do the work of protein enzymes - Phys.Org | BS2064: Bioinformatics | Scoop.it
DNA catalysts do the work of protein enzymes Phys.Org U. of I.
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Synthesized DNA catalysts do the work of protein enzymes - R & D Magazine

Synthesized DNA catalysts do the work of protein enzymes R & D Magazine “Protein enzymes are the workhorses of biology,” Silverman said. “They do most of the catalytic activity.
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Hmm, ambitious and is it art: Art Emerges from DNA Left Behind - Wall Street Journal

Hmm, ambitious and is it art: Art Emerges from DNA Left Behind - Wall Street Journal | BS2064: Bioinformatics | Scoop.it
Wall Street Journal Art Emerges from DNA Left Behind Wall Street Journal After reading online about genetic research, Ms.
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DNA Sequencing Giant Illumina Joins Hunt for Autism Blood Test - MIT Technology Review

DNA Sequencing Giant Illumina Joins Hunt for Autism Blood Test - MIT Technology Review | BS2064: Bioinformatics | Scoop.it
MIT Technology Review DNA Sequencing Giant Illumina Joins Hunt for Autism Blood Test MIT Technology Review Massachusetts startup SynapDx announced on Wednesday that it will work with DNA sequencer manufacturer Illumina to develop early detection...
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Cellular Metabolism Changes Could Trigger Type 2 Diabetes - RedOrbit

Cellular Metabolism Changes Could Trigger Type 2 Diabetes - RedOrbit | BS2064: Bioinformatics | Scoop.it
RedOrbit Cellular Metabolism Changes Could Trigger Type 2 Diabetes RedOrbit Changes in a person's cellular metabolism, not genetic predisposition, may be the primary factor that causes a person to contract Type 2 diabetes, researchers from the...
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Futurity.org – DNA uncovers identical deadly sea snakes

Futurity.org – DNA uncovers identical deadly sea snakes | BS2064: Bioinformatics | Scoop.it
DNA uncovers identical deadly sea snakes. The two species occupy the same specialized habitat of silt-filled shallows of tropical estuaries in Asia and Australia. The beaked sea snakes are responsible for the majority of ...
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The ISME Journal - Metagenome, metatranscriptome and single-cell sequencing reveal microbial response to Deepwater Horizon oil spill

The ISME Journal - Metagenome, metatranscriptome and single-cell sequencing reveal microbial response to Deepwater Horizon oil spill | BS2064: Bioinformatics | Scoop.it
The ISME Journal: Multidisciplinary Journal of Microbial Ecology is the official Journal of the International Society for Microbial Ecology, publishing high-quality, original research papers, short communications, commentary articles and reviews in...
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The Junk in Your Genetic Trunk | Virology and Bioinformatics from Virology.ca

The Junk in Your Genetic Trunk | Virology and Bioinformatics from Virology.ca | BS2064: Bioinformatics | Scoop.it
Almost every cell in your body contains, at its centre, a small tangle of genetic information .
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